Avaliaçao do efeito do extrato de casca de cajueiro-branco (Anacardium occidentale L.) Sobre A infecção por Leishmania (Viannia) brasiliensis

França, Flávio; Cuba, César Augusto Cuba; Moreira, Eduardo A.; Miguel, Obdúlio; Almeida, Marcos de; Virgens, Maria de L. das; Marsden, Philip D.

doi:10.1590/s0037-86821993000300004

Cited by 23 publications

(11 citation statements)

References 6 publications

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“…Recentes estudos demonstraram o uso de plantas medicinais no tratamento de lesões ulceradas da leishmaniose tegumentar e também em modelos in vitro (França et al, 1993;Fournet et al, 1992b;Akendengue et al, 1999;Moreira et al, 2002;Mesia-Vela et al, 2004;Paula-Junior et al, 2006;Bezerra et al, 2006).…”

Section: Discussionunclassified

Efeito leishmanicida in vitro de Stachytarpheta cayennensis (Rich.) Vahl (Verbenaceae)

Moreira¹,

Costa²,

Lopes³

et al. 2007

Rev. bras. farmacogn.

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RESUMO:ABSTRACT: "In vitro leishmanicidal effect of Stachytarpheta cayennensis (Rich.) Vahl (Verbenaceae)". Leishmanicidal activity of the hydroalcoholic extract of Stachytarpheta cayennensis, species that is usually employed in ulcers caused by Leishmania, was evaluated in vitro using Leishmania braziliensis and L. amazonensis promastigotes forms. The hydroalcoholic extract was prepared from dried leaves and used in L. amazonensis and L. braziliensis promastigotes cultures at concentrations of 500 to 32.5 g/mL. After 24 hours the promastigotes forms were quantifi ed and the IC 50 was calculated. The cytotoxicity of the extract was evaluated using peritoneal macrophages. The extract presented a dose and specie-dependent leishmanicidal effect to Leishmania promastigotes, mainly to the L. braziliensis ones. The cytotoxic effect was not observed in macrophage cultures. In conclusion, the hydroalcoholic extract of S. cayennensis inhibits the growing of Leishmania promastigotes forms in vitro accounting for the folk use of this vegetal in skin ulcers caused by Leishmania.

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Section: Discussionunclassified

Efeito leishmanicida in vitro de Stachytarpheta cayennensis (Rich.) Vahl (Verbenaceae)

Moreira¹,

Costa²,

Lopes³

et al. 2007

Rev. bras. farmacogn.

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“…It belongs to the family of the flowering plant, Anacardiaceae, whose leaves and/or the stem barks have been used for treatment of eczema, diarrhea, dysentery, colonic pains, genital problems, venereal diseases, impotence, bronchitis, cough and syphilis-related skin disorders [6,7]. It has also been reported to possess anti-diabetic, anti-inflammatory anti-microbial and anti-ulcerogenic properties [8].…”

Section: Introductionmentioning

confidence: 99%

Comparative Studies of the Phytochemical, Antioxidant and Antimicrobial Properties of Cashew Leaf, Bark and Fruits Extracts

Onuh¹,

Idoko²,

Yusufu³

et al. 2017

AJFN

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Extracts of the leaf, stem bark and fruit of cashew plants were investigated to determine their phytochemical, antioxidant and antimicrobial properties. Cashew leaves, stem barks and fruits of the Brazilian Jumbo variety were processed, extracted and analyzed for their phytochemical, antioxidant and antimicrobial activities. The results showed that the phytochemical contents varied significantly between the sample extracts. Carotenoids content of cashew extracts are 88.86, 125.93 and 100.33 mg/g for the leaf, bark and fruit respectively. The stem bark extract showed significantly highest tannin content (2.01 mg/g) compared to the cashew fruit extract (1.56 mg/g) and cashew leaf extract (1.19 mg/g). Total phenolic content of the cashew plant parts varied significantly from 103.92 -983 .23 mg/g sample of the extract with the leaf extract having significantly lowest value while the fruit had the highest value. Cashew fruit extract exhibited significantly highest percentage DPPH scavenging activity at all concentrations. There was a positive correlation between the total phenolic content and antioxidant activities of cashew extracts suggesting that the phenolic content may directly influence the antioxidant activities. Extracts of cashew leaves and stem barks exhibited appreciable inhibition on all human pathogens screened compared to the fruit extract which was only active against salmonella typhi. Cashew extracts could therefore be used as a potential source of ingredients in the development of nutraceuticals and functional foods for the control, management and treatment of health disorders.

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“…The hydroalcoholic extract of A. occidentale bark showed high in-vitro activity against the promastigotes of the species Leishmania (Viannia) braziliensis (Franca et al 1993). However, in the in-vivo model no therapeutic activity was observed.…”

Section: Antileishmanial Activitymentioning

confidence: 97%

Anacardium occidentale

Lim¹

2011

Edible Medicinal and Non-Medicinal Plants

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Avaliaçao do efeito do extrato de casca de cajueiro-branco (Anacardium occidentale L.) Sobre A infecção por Leishmania (Viannia) brasiliensis

Cited by 23 publications

References 6 publications

Efeito leishmanicida in vitro de Stachytarpheta cayennensis (Rich.) Vahl (Verbenaceae)

Efeito leishmanicida in vitro de Stachytarpheta cayennensis (Rich.) Vahl (Verbenaceae)

Comparative Studies of the Phytochemical, Antioxidant and Antimicrobial Properties of Cashew Leaf, Bark and Fruits Extracts

Anacardium occidentale

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