Patologia da forma aguda, toxêmica, da esquistossomose mansoni

Raso, Pedro; Pedroso, Ênio Roberto Pietra; Neves, Jorge Tadeu de Ramos

doi:10.1590/s0037-86821986000100011

Cited by 5 publications

(7 citation statements)

References 28 publications

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“…Microvacuolated hepatocytes were visible adjacent to the eggs, coagulative necrosis was evident, and the area was surrounded by eosinophils (9 (215). Clinical manifestations seen in patients, i.e., skin rash, eosinophilia, pulmonary edema, or diarrhea, are consistent with this contention (36,106,234). The temporal relationship between the appearance of symptoms and the release into the circulation of large amounts of worm antigens derived from VOL.…”

Section: Introductionmentioning

confidence: 63%

“…The acute (toxemic) syndrome is manifested by fever, malaise, hepatosplenomegaly, eosinophilia, diarrhea, and, in some cases, edema, urticaria. lymphadenopathy, and arthralgia (106,200,234,277). These symptoms are transient and spontaneously disappear with the passage of the infection to the chronic stage.…”

Section: Introductionmentioning

confidence: 99%

“…Moderate elevation in serum globulin, serum glutamic oxalacetic transaminase, and serum glutamic pyruvic transaminase levels may occur, indicating liver involvement. In rare cases, acute hepatitis with focal necrosis and eosinophil infiltration are observed (234). The efficacy of antihelminthic therapy at this phase of the infection is equivocal (200).…”

Section: Introductionmentioning

confidence: 99%

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Immunopathology of Schistosoma mansoni infection

1989

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Schistosomiasis mansoni is a chronic helminthic disease that affects about 100 million people in the tropics. The worms have a life span of 5 to 10 years, and they live in the mesenteric veins of the host. Lightly infected individuals are asymptomatic or manifest mild intestinal symptoms. Heavily infected individuals often develop severe morbidity with hepatosplenomegaly, sometimes with a fatal outcome. Morbidity is attributed to the strong humoral and T-cell-mediated host immune responses developed to a variety of parasite antigens and expressed as tissue inflammations. The immunopathology includes dermatitis, immune complex-mediated kidney disease, and, chiefly, T-cell-mediated granuloma formation and fibrosis around disseminated parasite eggs. This review describes the mechanisms of induction and expression of immunopathology in infected persons and experimental animals. Immunoregulatory mechanisms that modulate the enhanced immune responses and may ameliorate excessive morbidity are discussed.

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Section: Introductionmentioning

confidence: 63%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Immunopathology of Schistosoma mansoni infection

1989

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“…The symptoms are usually accompanied by other, less common manifestations, such as hepatosplenomegaly, diarrhea, urticaria, and edema [10,11]. Katayama fever occurs in a varying percentage of persons exposed to Schistosoma species, and it appears around the period of early oviposition.…”

Section: The Disease In Travelersmentioning

confidence: 99%

Schistosomiasis and International Travel

Corachán

2002

CLIN INFECT DIS

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Infection with Schistosoma species is acquired by exposure to fresh water that harbors cercariae released by infected snails. Although the route of infection is clear, clinical presentation of the established infection in the nonimmune tourist typically differs from that in the local population of areas of endemicity. For the health care practitioner, the traveler's syndrome presents distinctive management problems: water-transmitted bacterial and viral infections may coexist, and identification of the stage of disease at presentation, along with identification of the causative species, will maximize treatment options. Travel medicine clinics serve as epidemiological antennae, helping to identify the dynamics of species transmission in geographically distinct areas. Education of persons traveling to areas of endemicity and the development of mechanical protection against exposure are needed.

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“…Acute schistosomiasis is a clinical syndrome often seen in nonimmune individuals (tourists, immigrants, or the indigenous population) who have been exposed in an endemic area to a primary infection by cercariae (79,106,234,300). The syndrome is sometimes called Katayama fever, described in Japan in persons who acquired a massive infection with S. japoniuizn worms.…”

Section: Acute Schistosomiasismentioning

confidence: 99%

Immunopathology of Schistosoma mansoni infection.

Boros¹

1989

Clinical Microbiology Reviews

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Patologia da forma aguda, toxêmica, da esquistossomose mansoni

Cited by 5 publications

References 28 publications

Immunopathology of Schistosoma mansoni infection

Immunopathology of Schistosoma mansoni infection

Schistosomiasis and International Travel

Immunopathology of Schistosoma mansoni infection.

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