Micose de Lobo

Silva, Domingos

doi:10.1590/s0037-86821972000200005

Cited by 18 publications

(16 citation statements)

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“…1b and 1c). 48–52 The lesions may be single or multiple. They have a tendency to become confluent over extensive areas of the body surface 51,52 .…”

Section: Clinical Featuresmentioning

confidence: 99%

Lobomycosis: an emerging disease in humans and delphinidae

Paniz-Mondolfi

Talhari

Hoffmann

et al. 2012

Mycoses

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Summary Lobomycosis, a disease caused by the uncultivable dimorphic onygenale fungi Lacazia loboi, remains to date as an enigmatic illness, both due to the impossibility of its aetiological agent to be cultured and grown in vitro, as well as because of its unresponsiveness to specific antifungal treatments. It was first described in the 1930s by Brazilian dermatologist Jorge Lobo and is known to cause cutaneous and subcutaneous localised and widespread infections in humans and dolphins. Soil and vegetation are believed to be the chief habitat of the fungus, however, increasing reports in marine mammals has shifted the attention to the aquatic environment. Infection in humans has also been associated with proximity to water, raising the hypothesis that L. loboi may be a hydrophilic microorganism that penetrates the skin by trauma. Although its occurrence was once thought to be restricted to New World tropical countries, its recent description in African patients has wrecked this belief. Antifungals noted to be effective in the empirical management of other cutaneous/subcutaneous mycoses have proven unsuccessful and unfortunately, no satisfactory therapeutic approach for this cutaneous infection currently exists.

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“…1b and 1c). 48–52 The lesions may be single or multiple. They have a tendency to become confluent over extensive areas of the body surface 51,52 .…”

Section: Clinical Featuresmentioning

confidence: 99%

Lobomycosis: an emerging disease in humans and delphinidae

Paniz-Mondolfi

Talhari

Hoffmann

et al. 2012

Mycoses

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“…There are no reports of involvement of the general condition of the patients, except when there is extensive ulceration of the lesions with secondary infection 25 . When there are multiple large lesions, besides the deformity, the itching becomes unbearable 34 .…”

Section: Introductionmentioning

confidence: 99%

“…SILVA 25 and SILVA & DE BRITO 27 proposed a clinical classification based on the morphology of the lesions: infiltrative, keloid-like, in plaques, verruciform and ulcerated. According to BARUZZI & AZEVEDO 1 and LACAZ et al 11 to facilitate surgical excision, lesions were classified according to their distribution: 1) isolated or localized forms and 2) disseminated forms.…”

Section: Introductionmentioning

confidence: 99%

Ten years experience with Jorge Lobo's disease in the state of Acre, Amazon region, Brazil

Woods¹,

Belone

Carneiro³

et al. 2010

Rev. Inst. Med. trop. S. Paulo

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SUMMARYJorge Lobo's disease is a cutaneous and subcutaneous mycosis that affects patients in the Amazon region. The number of patients is relatively small, but the real situation of the disease as public health problem is not known, because Jorge Lobo's disease is not a notifiable disease. This study aims to report the clinical evolution in patients affected and to determine the prevalence and areas of occurrence of the disease. A retrospective study was carried out based on the analysis of the clinical records, which included a collection of photographs of patients in the Department of Sanitary Dermatology, in Rio Branco, and patients seen in the interior of the state. In a decade, in Rio Branco, 249 cases of the disease were reported, 30 were females and 219 males. Of these patients, 153 had localized lesions, 94 of them were on one ear, 55 had multifocal lesions and 41 had disseminated lesions. The average time between the onset of symptoms and diagnosis was 19 years. The average age at the time of diagnosis was 53 years, and ages ranged from 14 to 96 years.

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“…Clinically, the mycosis is characterized by cutaneous lesions of with a cheloid-like, wart-like infiltrative, ulcerous or gummy aspect, with the possible occurrence of more than one type of lesion in the same patient 16 . Ulcerated lesions seem to be a result of traumatic injuries more than to primary spontaneous ulceration and therefore are clinically secondary 11 .…”

mentioning

confidence: 99%