In vitro antimalarial activity and cytotoxicity of some selected cuban medicinal plants

Valdés, Aymé Fernández-Calienes; Martínez, Judith Mendiola; Lizama, Ramón Scull; Gaitén, Yamilet Gutiérrez; Rodríguez, Daniel Salazar; Payrol, Juan Abreu

doi:10.1590/s0036-46652010000400006

Cited by 53 publications

(39 citation statements)

References 31 publications

(27 reference statements)

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“…Corroborating the data found in this study, Valdés et al (2010) confirmed the presence of quinones, phenols, triterpenes, lactonic compounds, alkaloids, steroids, amino acids, saponins and flavonoids.…”

Section: Phytochemical Analysissupporting

confidence: 88%

Biological Activity of Bambusa vulgaris Schrad. ex J.C. Wendl. (Poaceae)

Alencar¹,

Silva²,

Figueiredo³

et al. 2015

JAS

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This study aims to evaluate the allelopathic activity of Bambusa vulgaris Schrad. ex J.C. Wendl., invasive species in an area of Cerrado in the Chapada do Araripe in Ceará. The treatments consisted of the aqueous extract in concentrations of 25, 50, 75 and 100% and a Control (distilled water), with five replicates containing 20 seeds each. The tests were carried out in the laboratory and in a greenhouse, using corn and beans as the test seeds. The parameters analyzed were number of germinated seeds, measurement of caulicle and radical length, occurrence of radicle necrosis and germination speed index (GSI). The results obtained from the laboratory bioassays on corn seeds indicate that the extract affected development of the seedlings, reducing caulicle growth and increasing radicle length, in addition to causing radicle necrosis. Regarding the bean seeds, there was a delay in the GSI, reduced caulicle growth and radicle necrosis. In the bioassay conducted in the greenhouse, for the corn seeds the extract inhibited germination and both caulicle and radicle growth, as well as delaying the GSI. When tested on the beans, the extract provoked reduction in the number of germinated seeds at the higher concentrations, delayed the GSI, reduced the radicle size and caused radicle necrosis. The allelopathic effects observed in the greenhouse were more significant, suggesting that environmental factors in conjunction with the action of the allelochemicals interfered more actively with the seed germination and seedling development of the receptor species.

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Section: Phytochemical Analysissupporting

confidence: 88%

Biological Activity of Bambusa vulgaris Schrad. ex J.C. Wendl. (Poaceae)

Alencar¹,

Silva²,

Figueiredo³

et al. 2015

JAS

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“…Isolation of 4-phenylpropanoids from Australian species of C. ambiguus has been reported. These compounds are eugenol (4-allyl-2-methoxyphenol) (18); elemicin (5-allyl-1,2,3-trimethoxybenzene) (19); eugenol methylether (4-allyl-1,2-dimethoxybenzene) (20) and trans-iso-elemicin (1,2,3-trimethoxy-5-(1-propenyl) benzene) (21) and all these isolates exhibited good inhibition activity against ADP-induced human platelet serotonin release which is associated with headaches [26].…”

Section: Flavonoidsmentioning

confidence: 99%

Cymbopogon Species; Ethnopharmacology, Phytochemistry and the Pharmacological Importance

et al. 2015

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Abstract:Cymbopogon genus is a member of the family of Gramineae which are herbs known worldwide for their high essential oil content. They are widely distributed across all continents where they are used for various purposes. The commercial and medicinal uses of the various species of Cymbopogon are well documented. Ethnopharmacology evidence shows that they possess a wide array of properties that justifies their use for pest control, in cosmetics and as anti-inflammation agents. These plants may also hold promise as potent anti-tumor and chemopreventive drugs. The chemo-types from this genus have been used as biomarkers for their identification and classification. Pharmacological applications of Cymbopogon citratus are well exploited, though studies show that other species may also useful pharmaceutically. Hence this literature review intends to discuss these species and explore their potential economic importance.

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“…In herbal medicine, S. jamaicensis itself has been known to demonstrate antacid, analgesic [13], anti-inflammatory [12], hypotensive [3], antihelminthic [14], diuretic, laxative, lactagogue, purgative, sedative, spasmogenic, vasodilator, vulnerary, and vermifuge properties [1, 8, 15]. …”

Section: Traditional Usage Of Stachytarpheta Jamaicensismentioning

confidence: 99%

Stachytarpheta jamaicensis (L.) Vahl: From Traditional Usage to Pharmacological Evidence

Liew

Yong

2016

Evidence-Based Complementary and Alternative Medicine

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Introduction. Stachytarpheta jamaicensis (L.) Vahl belongs to the family of Verbenaceae and is commonly known as Gervao, Brazilian tea, verbena cimarrona, rooter comb, or blue porter weed. It is one of the important plants with high medicinal and nutraceutical benefits. S. jamaicensis contains various medicinal properties in traditional and folk medicinal systems, with cures for several diseases. Objective. The objective of this review paper is to collect information concerning the morphology, distribution, traditional usage, phytochemical compositions, biological activities, and safety data of S. jamaicensis. Materials and Methods. The information was obtained from literature search through electronic databases such as PubMed and Google Scholar on S. jamaicensis. Results and Conclusion. The high medicinal properties of this plant, for instance, antimicrobial and antifungal effect as the main activities, but verbascoside as the main active chemical component, make it a valuable source of the medicinal compound. This review paper summarizes all information concerning the morphology, distribution, traditional usage, phytochemical compositions, pharmacological activities, and toxicological studies of S. jamaicensis.

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In vitro antimalarial activity and cytotoxicity of some selected cuban medicinal plants

Cited by 53 publications

References 31 publications

Biological Activity of Bambusa vulgaris Schrad. ex J.C. Wendl. (Poaceae)

Biological Activity of Bambusa vulgaris Schrad. ex J.C. Wendl. (Poaceae)

Cymbopogon Species; Ethnopharmacology, Phytochemistry and the Pharmacological Importance

Stachytarpheta jamaicensis (L.) Vahl: From Traditional Usage to Pharmacological Evidence

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