2001
DOI: 10.1590/s0036-46652001000200002
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Schistosoma mansoni: inflammatory foci around larvae in the peritoneal cavity of naive mice is radiosensitive

Abstract: SUMMARYInnate attack to Schistosoma mansoni cercariae was evaluated in irradiated mice. It was observed that 70% of the larvae from mice sacrificed one day after whole body irradiation with 400 or 800 rads were surrounded by cluster reactivities, without difference from controls. Differences were apparent on day 5 after irradiation with sub lethal (400 rads) or lethal doses (800 rads) suggesting that innate defence to infection take at least 5 days to be affected by low dose whole-body radiation.

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Cited by 3 publications
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“…However, in experimental studies in mice, after direct intraperitoneal inoculation of the parasite there was evidence of eggs in the omentum and peritoneum 37 . These findings suggest that the parasite is able to develop without ingestion of red blood cells (intravascular localization) and may explain the presence of Schistosoma eggs in human omentum.…”
Section: Discussionmentioning
confidence: 99%
“…However, in experimental studies in mice, after direct intraperitoneal inoculation of the parasite there was evidence of eggs in the omentum and peritoneum 37 . These findings suggest that the parasite is able to develop without ingestion of red blood cells (intravascular localization) and may explain the presence of Schistosoma eggs in human omentum.…”
Section: Discussionmentioning
confidence: 99%