Experience in the Evaluation of Children With Hepatosplenomegaly at a Teaching Ambulatory, São Paulo, Brazil

Abstract

Most of the children with HS present deficiency anemia associated with infections which the general pediatrician is able to diagnose. Persistence of unexplained HS for more than 2 months, especially when there is substantial volume enlargement or alteration in the organs consistency, is an indication for referral to specialists.

Study of aetiological profile, clinical presentation and outcome of hepatosplenomegaly in children between 1 month and 14 years of age

“…Similar presentation was found by Somaiah G et al and Bricks et al 12,13 The greater incidence of anemia in our study is due to greater prevalence of haemolytic anemia in our population group. Infectious causes are commonest etiology followed by haematological and congestive causes in our study.…”

“…Among infectious causes commonest being malaria followed by septicaemia. Similar observation was found by Somiah G et al, Bricks et al 12,13 Ali N et all found that most common etiology was haematological followed by malignancy and infective.…”

“…The major etiologies of hepatosplenomegaly in children in our study can be compared to results of similar study conducted by Bricks LF et al and Ali N et al 13,14 as follows (Table 5). In our study, death was maximum in congestive causes (55.6%) which was statistically significant demonstrated by p value of 0.002 followed by infectious causes (22.7%) which was also statistically significant demonstrated by p value of 0.001 (Table 6) whereas death was minimum in haematological causes (0%) which was also statistically significant represented by p value of 0.001 whereas all the cases of connective tissue diseases were referred.…”