Study of aetiological profile, clinical presentation and outcome of hepatosplenomegaly in children between 1 month and 14 years of age

Champatiray, Jyotiranjan; Panigrahi, Debasish; Mondal, Dodul; Satpathy, Saroj Kumar

doi:10.18203/2349-3291.ijcp20171700

Cited by 3 publications

(3 citation statements)

References 7 publications

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“…In the infectious group, 29.33% were due to Malaria, 13.33% were of Enteric Fever, 11.33% were due to Viral Hepatitis, 6.67% due to Tuberculosis, 4.67% due to Dengue fever, 2.67% are due to Septicemia [7] . In champatiray et al study, infections were the most common cause of Splenomegaly constituting 50% of the cases of which Malaria was most common [10] .…”

Section: Discussionmentioning

confidence: 92%

Assessment of etiological factors and clinical outcome of splenomegaly among the children admitted under paediatric department, Siddipet district, Telangana state

Rajender¹,

Patruni²

2020

Int. J. Paediatrics Geriatrics

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Introduction: Splenomegaly is defined as enlargement of spleen. Splenomegaly is a sign which is prominent among infants and children. Aim of this study is to assess the various etiological factors and clinical outcome of splenomegaly among the pediatric cases admitted in RVM Institute of Medical Sciences and Research Centre, Siddipet, Telangana state. Methodology: Hospital based observational study conducted between July 2019 to December 2019. 50 children from 6 months to 18years, with varying grades of Splenomegaly of different etiologies, admitted to pediatric ward of RVM Institute of Medical Sciences, Siddipet. Detailed History was collected by administering semi-structured questionnaire on each case, physical examination and necessary investigations were done wherever required. Results: Male preponderance was seen in present study. Maximum incidence of Splenomegaly was seen between 6 months to 6 years age group (56%).Majority of the cases had moderate Splenomegaly (46.15%). Fever was the most common presenting feature associated with Splenomegaly. Infections (44%) were the most common Cause of Splenomegaly in all study followed by hematologic diseases (36%). Conclusion:Occurrence of Splenomegaly is commonly due to various infections in present study. Males are predominantly having splenomegaly; majority of cases had moderate Splenomegaly.

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Section: Discussionmentioning

confidence: 92%

Assessment of etiological factors and clinical outcome of splenomegaly among the children admitted under paediatric department, Siddipet district, Telangana state

Rajender¹,

Patruni²

2020

Int. J. Paediatrics Geriatrics

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“…and Jayalaxmi (8) in their study of splenomegaly in infants and children found that hepatomegaly was an associated finding in 96% cases of splenomegaly. Champatiray J et al (9) and Somaiah G et al (10) were previous studies that provided insight into the etiology of hepatomegaly in children. Chart 2…”

Section: Discussionmentioning

confidence: 99%

Study of Etiological and Clinical Profile of Hepatomegaly in Children up to 10 years of Age

Agrawal¹

2019

jmscr

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Background: Liver enlargement could be an indicator of underlying liver disease, even if there are usually no symptoms associated with it. On the other hand, Symptoms of a grossly enlarged liver include abdominal discomfort or feeling full could potentially provide an insight into an underlying serious pathology It could be due to a various number of infective/Inflammatory, Congestive, infiltrative, proliferative (Kupfer cell) reasons. It could also be a manifestation of an underlying intrinsic hepatic disorder and Storage related disorders. Material and Methods: All children upto the age of one month to 10 years presenting to Hitech Medical College and Hospital with increase in liver span were included in the study over the span of the past year. Patients were subjected to routine investigations and in some cases some special investigations depending on provisional diagnosis after detailed history and physical examination. Results and Conclusion:The most common age group presenting with hepatomegaly was found to be between 1 to 5 years followed by 5 to 10 years. The most common aetiology was found to be infections and the most common presenting signs and symptoms were found to be fever, anemia followed by oedema and jaundice.

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“…Abnormal increase in the size of liver and spleen is called hepatosplenomegaly. 9 Usually, the spleen is said to have increased in size when it moves below left costal margin. 10 The liver is said to have increased in size when its lower margin goes below the right costal margin.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic utility of bone marrow aspiration biopsy in definitive diagnosis in cases of hepatosplenomegaly.

Sami¹,

Khan

Iqbal

2021

TPMJ

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Objective: To determine the diagnostic utility of bone marrow aspirate in finding cause of hepatosplenomegaly. Study Design: Cross Sectional Descriptive study. Setting: Pathology Department of Khyber Teaching Hospital. Period: August 2017 to December 2017. Material & Methods: A total of 116 cases were referred to Pathology department for workup of hepatosplenomegaly during study period. Patients were subjected to bone marrow aspiration and biopsy. The cases were diagnosis was made and those where no specific diagnosis could be made were noted. Mean and standard deviation were used for quantitative variables. Frequency and percentages were used for qualitative variables. Results: Mean age of the study sample was 45±9 years (range 2 -64 years). There were 66 (56.89%) males and 50 (43.10%) females. No specific diagnosis could be made in 36 (31.03%) cases of hepatosplenomegaly. In remaining 80 (68.96%) cases a definitive diagnosis could be made on examining bone marrow aspiration. So the diagnostic utility of bone marrow aspiration examination was 68.96%. Conclusion: Bone marrow aspiration is valuable and diagnostically important tool for workup of cases of hepatosplenomegaly.

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Study of aetiological profile, clinical presentation and outcome of hepatosplenomegaly in children between 1 month and 14 years of age

Cited by 3 publications

References 7 publications

Assessment of etiological factors and clinical outcome of splenomegaly among the children admitted under paediatric department, Siddipet district, Telangana state

Assessment of etiological factors and clinical outcome of splenomegaly among the children admitted under paediatric department, Siddipet district, Telangana state

Study of Etiological and Clinical Profile of Hepatomegaly in Children up to 10 years of Age

Diagnostic utility of bone marrow aspiration biopsy in definitive diagnosis in cases of hepatosplenomegaly.

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