Human lagochilascariasis treated sucessfully with ivermectin: a case report

Abstract

A 15 year old male patient was diagnosed as being infected with the nematode Lagochilascaris minor, presenting as abscesses over the left mastoid region, and invading the temporal bone, mastoid sinuses and possibly the CNS. Surgical drainage and administration of cambendazole and levamisole led to improvement, followed by an early relapse and poor tolerance to the antihelminthic drugs. Repeated doses of ivermectin (an animal preparation) were used for the first time to treat this condition and resulted in complete remission of signs of infection, maintained for 15 months after the end of drug therapy, indicating cure of the disease.

Avaliação de alterações timpanométricas em pacientes submetidos à anestesia geral com óxido nitroso

“…We studied whether the affected ear (right/left) would be related with homolateral septum deviation. This was thought because anatomical affections, such as septal malformation, could selectively affect drainage and the protective functions of ME 22 . However, we did not find any evidence of this association.…”

“…In other words, its opening is determined by active movements, and its is physiologically reached by swallowing and yawning. Ostium closure is a passive movement made by relaxation of the muscle 22 .…”

“…Drainage of secretions to the nasopharynx is made by one of two ways: the mucociliary system, and the active mechanisms of auditory tube opening 22,25 . A normal tube easily balances differences of pressure, through frequent opening with passage of small volume of air: 1 to 1.5 milliliter 22 .…”

“…A normal tube easily balances differences of pressure, through frequent opening with passage of small volume of air: 1 to 1.5 milliliter 22 . In anesthetized patients, equalization of pressure depends on passive opening of the tube.…”

“…However, owing to quick reabsorption of anesthetic, there may be negative intratympanic pressure 8,10 . It could provide occurrence of transudate from the local mucosa, reducing the gas volume in the ear, and consequently, its pressure 22 .…”