Environmental lead poisoning among children in Porto Alegre state, Southern Brazil

Ferron, Mariana Maleronka; Lima, André Klafke de; Saldiva, Paulo Hilário Nascimento

doi:10.1590/s0034-89102012000200004

Cited by 21 publications

(13 citation statements)

References 12 publications

(17 reference statements)

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“…There were 13 studies of children living in the neighborhood of leadcontaminated areas in the northeast region, [80][81][82][83][84][85][86][87] the southeast region (State of Sao Paulo), [88][89][90][91] and the south region (State of Rio Grande do Sul). 92 One study was done in an area contaminated with aluminum 93 and another in an area contaminated with arsenic. 94 In all of these studies, the distance between the place of residence and the pollution source was correlated with levels of metal in the children.…”

mentioning

confidence: 99%

A Systematic Review of Children's Environmental Health in Brazil

Asmus

Câmara

Landrigan

et al. 2016

Annals of Global Health

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In the region of the Americas, approximately 100,000 children under the age of 5 years die each year due to environmental hazards. Brazil, due to its large size and wide range of environmental challenges, presents numerous hazards to children's health. The aim of this study was to systematically review the scientific literature that describes children's exposures to environmental pollutants in Brazil and their effects on Brazilian children's health. A systematic review of the scientific literature was performed without language restrictions and time of publication (years). The literature search was conducted in the following key resources: PubMed (MEDLINE), Scopus and Web of Science with the MeSH Terms: Environmental exposure AND Brazil (filters: Human, Child [birth to 18 years] and Affiliation Author). The Virtual Health Library was also employed to access the databases Scielo and Lilacs. The search strategy was [DeCS Terms]: Child OR adolescent AND Environmental exposure AND Brazil. Health effects in children associated with exposure to environmental pollutants in Brazil were reported in 74 studies, during the period between 1995 and 2015. The most frequently cited effect was hospital admission for respiratory causes including wheezing, asthma, and pneumonia among children living in areas with high concentrations of air pollutants. A broad spectrum of other health effects possibly linked to pollutants also was found such as prematurity, low birth weight, congenital abnormality (cryptorchidism, hypospadia, micropenis), poor performance in tests of psychomotor and mental development, and behavioral problems. Exposure to pesticides in utero and postnatally was associated with a high risk for leukemia in children <2 years old. These results show that there is a need in Brazil for stricter monitoring of pollutant emissions and for health surveillance programs especially among vulnerable populations such as pregnant women and young children.

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confidence: 99%

A Systematic Review of Children's Environmental Health in Brazil

Asmus

Câmara

Landrigan

et al. 2016

Annals of Global Health

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“…Aunque no hay publicaciones sobre la presencia de plomo y cadmio en agua, alimentos y peces en la región de La Mojana, las concentraciones de estos metales encontradas en la sangre de sus habitantes pueden estar relacionadas con la ingestión de aguas y alimentos contaminados (44,45). Probablemente, esto es consecuencia de dos procesos: en primer lugar, las constantes inundaciones provenientes del río Cauca, el cual recoge desechos tóxicos con presencia de estos metales generados por la actividad minera e industrial a lo largo de su recorrido (46) que son drenados a la zona, contaminando las aguas, los suelos y los alimentos.…”

Section: Discussionunclassified

Efectos genotóxicos en población humana asociados a metales pesados en la región de La Mojana, Colombia, 2013

Calao

Marrugo

2015

biomedica

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Contribución de los autores:Clelia Rosa Calao: ejecución del estudio en campo y realización de pruebas biológicas (ensayo cometa), análisis de resultados y redacción del artículo José Luis Marrugo: concepción y diseño del estudio, revisión del manuscrito en cuanto a la dinámica de la contaminación con metales pesados y su relación con la salud pública como aplicación de la vigilancia ambiental Introducción. En Colombia, la minería es una actividad económica importante; sin embargo, genera grandes cantidades de residuos que contienen elementos potencialmente tóxicos, como los metales pesados, que contaminan los ecosistemas y ponen en riesgo la salud humana. La región de La Mojana es una de las zonas más ricas en biodiversidad del planeta y se ha visto sometida a procesos de contaminación muy relacionados con la minería de oro que se desarrolla en sus alrededores. Objetivo. Evaluar la genotoxicidad en una población expuesta a residuos de metales pesados en la región de La Mojana. Materiales y métodos. Se evaluaron los efectos genotóxicos y su relación con la concentración de metales pesados (mercurio, cadmio y plomo) en muestras de sangre de la población expuesta y el grupo de control. El grupo expuesto lo conformaron habitantes de los municipios de Guaranda, Sucre, Majagual y San Marcos; en el grupo de control se incluyó a habitantes del municipio de Montería. Se determinó el daño en el ADN mediante el ensayo cometa en condiciones alcalinas. Las concentraciones de mercurio se establecieron mediante espectrometría de absorción atómica con vapor frío, en tanto que las de cadmio y plomo se determinaron por espectrometría de absorción atómica en horno de grafito. Resultados. Las concentraciones de los metales sobrepasaron los límites permitidos por la Organización Mundial de la Salud. Se evidenciaron efectos genotóxicos posiblemente asociados a la presencia de los metales en la sangre. Se encontraron asociaciones significativas (p<0,05) entre la presencia de mercurio y de cadmio, y el daño en el ADN. Conclusión. Estos resultados sugieren que el daño genético registrado en pobladores de la región de La Mojana, Colombia, puede estar asociado a la presencia de los metales estudiados en las muestras de sangre. Genotoxic effects in a human population exposed to heavy metals in the region of La Mojana, Colombia, 2013 Introduction: Mining is an economically important activity in Colombia which generates large quantities of residues containing potentially toxic elements such as heavy metals. These contaminate ecosystems and place human health at risk. La Mojana lies within one of the most biodiversity-rich zones on Earth and has been subjected to processes of contamination closely related to gold mining activities in the surrounding areas. Objective: To evaluate genotoxicity in the population of La Mojana region exposed to heavy metals. Materials and methods: Genotoxic effects and their relationship with concentrations of heavy metals (mercury, cadmium and lead) in blood were evaluated among an exposed population and a contr...

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“…Curvo [125] analyzed the positive prevalence of morbimortality due to cancer in adolescents in cities of the CO region, where there was an increase in grain harvesting and 48.91% of agrochemicals used were shown to be carcinogenic. [129] to estimate the prevalence of lead poisoning in children and to identify associated factors, as well as possible local sources of contamination crosssectional 16% blood lead levels ≥ 10.0 μg/dL 0 -5 y S male gender; age: 2,6 y; waste recylcing activities. ; soil, and air pollution.…”

Section: A Study On Incidence Of Clinical Hypoxic Ischemic Encephalopmentioning

confidence: 99%

“…Concerning the prevalence of lead poisoning, studies found blood lead levels ≥ 10.0 μg/dl, in children, associated with waste recycling [129] and residing close proximity to a battery factory [136]. Another study showed a strong association between adolescents with high dental enamel lead levels living in or close a contaminated area [131].…”

Section: Grandjean Et Almentioning

confidence: 99%