2008
DOI: 10.1590/s0034-89102008005000019
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Abstract: OBJECTIVE:To analyze the prevalence of IgG antibodies to human parvovirus B19. METHODS:Cross-sectional study in a suburban community in São Paulo, Southeastern Brazil, between November 1990 and January 1991. Randomly selected (N=435) representative samples of sera were collected from healthy children older than 15 days old and adults up to 40 years old. IgG antibodies were detected using ELISA. RESULTS:High prevalence of IgG antibodies to B19 parvovirus was found in 87% of newborns. The prevalence of maternall… Show more

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Cited by 11 publications
(4 citation statements)
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“…Frequencies of parvovirus-specific antibodies were similar to those of healthy children and other previously examined SCD pediatric populations. 6;7;26;27 …”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Frequencies of parvovirus-specific antibodies were similar to those of healthy children and other previously examined SCD pediatric populations. 6;7;26;27 …”
Section: Discussionmentioning
confidence: 99%
“…Frequencies of parvovirus-specific antibodies were similar to those of healthy children and other previously examined SCD pediatric populations. 6,7,26,27 Positive IgG results were recognized in approximately one-third of patients who had no documentation of prior transient aplastic crisis. This indicates that infection with parvovirus B19 does not cause clinically evident transient aplastic crisis in all SCD patients.…”
Section: Discussionmentioning
confidence: 99%
“…The use of a single probe also overcomes the need for additional probes to differentiate between genotypes 2 and 3. Although, data on B19V seroprevalence in Brazil are available [Wermelinger et al, 2002;Huatuco et al, 2008;Amaku et al, 2009], the epidemiological aspects of this infection in patients with hemoglobinopathies have not been evaluated. A single study [Sant'Anna et al, 2002], which included a significant number of patients with sickle cell disease, revealed low anti-B19 IgG reactivity (32.2%).…”
Section: Discussionmentioning
confidence: 99%
“…We considered a third model for parvovirus B19 infection, a mathematical model allowing for boosting and waning immunity, since lifelong protection against infection upon recovery from parvovirus B19 is questionable. [14][15][16][17] Goeyvaerts et al 18 considered several extensions of the MSIR model to account for waning of disease-acquired antibodies and/or for boosting of low immunity by exposure to infectious individuals. Here, we used the model with the best Akaike information criterion (AIC) value which was the compartmental model allowing for age-specific waning of disease-acquired antibodies and boosting of low immunity, denoted by "MSIRWb-ext AW" (see the Supplementary Material).…”
Section: Modelsmentioning
confidence: 99%