Infecção por Trypanosoma cruzi em candidatos a doador de sangue

Bonametti, Ana Maria; Filho, Adauto Castelo; Ramos, Luiz Roberto; Baldy, José Luís da Silveira; Matsuo, Tiemi

doi:10.1590/s0034-89101998000600010

Cited by 6 publications

(7 citation statements)

References 3 publications

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“…The results showed that the use of two or more different tests by blood banks prevents transfusion associated Chagas disease. Trypanosoma cruzi infection in blood donors Bonamett et al 15 1998 Revista de Saúde Pública Descriptive quantitative study: retrospective. To evaluate seropositivity for T. cruzi infection in blood donors and to compare this rate with those found in blood Banks in 1958 and 1975.…”

Section: Resultsmentioning

confidence: 99%

Chagasic infection among blood donors in Brazil: an integrative review

Cardoso¹,

Reis²,

Sousa

et al. 2018

Hematology, Transfusion and Cell Therapy

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Based on the literature, this work aimed to discuss infection by Chagas disease among blood donors in Brazil. Studies on the prevalence of Trypanosoma cruzi infection in donors or candidates for blood donation in Brazil are important. The prevalence of infection appears to be a sensitive indicator and can be a true marker of the risk of the transmission of Chagas disease by blood transfusion. Moreover, it serves as a marker of the level of transmission of the disease in a region, as well as a tool to characterize the epidemiological profile of individuals affected by the disease. The present study is an integrative review of the literature on chagasic infection among blood donors. An evaluation of the literature identified the epidemiological profile of blood donors infected by T. cruzi, which is characterized in general as men, over 30 years old, with a low level of schooling, low income and mainly coming from rural areas.

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Section: Resultsmentioning

confidence: 99%

Chagasic infection among blood donors in Brazil: an integrative review

Cardoso¹,

Reis²,

Sousa

et al. 2018

Hematology, Transfusion and Cell Therapy

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“…The countries with the highest prevalence of T. cruzi 3 . The manifestation of the chronic disease has a considerable geographic variation.…”

Section: Discussionmentioning

confidence: 99%

A sixty-four-year-old woman with Chagas' disease, who underwent implantation of a permanent cardiac pacemaker and evolved with rapidly progressive heart failure

Medeiros¹,

Benvenuti²,

Costa³

2001

Arq. Bras. Cardiol.

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A 64-year-old female patient sought medical assistance at our hospital due to dyspnea on light exertion and even at rest.The patient had been experiencing dyspnea on strenuous exertion since the age of 52 years, which progressed in 10 years to dyspnea on light exertion and even orthopnea.On physical examination (9/1/97), her pulse was regular, her heart rate was 56bpm, and her blood pressure was 140/170mmHg. Her lung examination was within the normal range. The cardiac ictus could be felt on the left 6 th intercostal space over the length of 2 fingertips. A systolic thrill was palpated on the 6 th intercostal space. The cardiac sounds were normal. A systolic cardiac murmur (++/4) was heard on the mitral area and a diastolic cardiac murmur was heard on the aortic area. The abdominal examination was within the normal range and no edema of the lower limbs was observed.The chest X-ray showed enlargement of the cardiac silhouette (++++/4) and normal pulmonary fields.Electrocardiography (8/27/97) showed an ectopic atrial rhythm, a P-R interval of 0.12 s, an initial disturbance of ventricular depolarization (initial QRS blurring in II, III, aVF, and V2), disorder of heart conduction of the anterosuperior left bundle-branch and the right branch, and alterations in ventricular repolarization ( fig. 1).The laboratory tests (8/27/97) were as follows: hemoglobin, 13.6g/dL; hematocrit, 39%; serum creatinine, 0.7mg/ dL; serum sodium, 141mEq/L; and serum potassium, 4.5mEq/L. The serum tests for Chagas' disease were positive.The diagnosis of heart failure due to Chagas' cardiomyopathy was established and the patient was prescribed 37.5mg of captopril and 25mg of hydrochlorothiazide daily.Echocardiography (12/18/97) showed diffuse hypokinesia of the left ventricle, ectasia of the aortic root, moderate regurgitation of the aortic and mitral valves, and pulmonary hypertension. The measurements are shown in table I.Chest tomography (3/31/99) revealed ectasia of the aortic root (52.66mm) and the following preserved diameters: ascending aorta (39.79mm), aortic arch (31.12mm and 25.76mm), descending aorta (26.27mm), and thoracoabdominal transition (21.4mm).The symptoms subsided, as did the dyspnea on moderate exertion. After 10 months, however, the dyspnea became more severe, being triggered on minimum exertion, and even orthopnea occurred (Sept '98). The patient then sought medical care, and an irregular cardiac rhythm was observed.Electrocardiography (9/3/98) showed an irregular rhythm of the atrial pacemaker with junctional escapes and ventricular premature depolarizations, QRS duration of 0.12 s, anterosuperior left bundle-branch block and block of the right branch ( fig. 2).Two months later, the patient required hospitalization (from 11/17/98 to 12/10/98) for control of heart failure.On physical examination (11/17/98), the patient had an irregular pulse, heart rate of 56 bpm, blood pressure of 110/ 80mmHg, crepitant rales in the base of her thorax, irregular cardiac rhythm due to frequent premature depolarizations, and a systolic...

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“…Furthermore, according to the Coordination of Blood and Hemoderivates of the Ministry of Health this figure for the state as whole had decreased to 0.86% in 1995 6 . In the city of Londrina, data collection carried out by various authors in the years of 1958, 1975, 1996 and 1998, found a decreasing seroprevalence of 6.92%, 7.49%, 1.4% and 1.3%, respectively 4,5,31,32 . Nowadays, with the main way of transmission under control, the principal concern is regarding assistance to infected individuals, particularly their situation in the job market, the social services involved and the necessity for adequate medical care 18 .…”

Section: Introductionmentioning

confidence: 99%

The epidemiologic profile and prevalence of cardiopathy in Trypanosoma cruzi infected blood donor candidates, Londrina, Paraná, Brazil

Oliveira-Marques

Bonametti

Matsuo

et al. 2005

Rev. Inst. Med. trop. S. Paulo

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To describe the epidemiologic profile and prevalence of cardiopathy in 163 Trypanosoma cruzi serum positive blood donor candidates, a descriptive study was carried out between August, 1996 and November, 1997 at the Londrina State University Chagas Disease Outpatient Clinic. The profile found was: young, average age 42.95 +/- 8.62 years; male (65%); Caucasian (84%); low level of schooling; low family income; agricultural worker (26%); born in the state of Paraná (67%); from rural areas (85%); migrated to the city (85%); and the vector as the main mechanism of transmission. During the clinical characterization a chronic cardiac form was found in 38% of the patients and classified as cardiac suggestive form in 21% and little suggestive of Chagas disease in 17%. No significant difference was found among age group distribution, sex and the presence of cardiac symptoms in patients with or without cardiopathy. This study emphasizes the importance of expanding medical services to areas with a greater prevalence of infected individuals, in a hierarchical manner and aiming at decentralization.

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Infecção por Trypanosoma cruzi em candidatos a doador de sangue

Abstract: BONAMETTI

Cited by 6 publications

References 3 publications

Chagasic infection among blood donors in Brazil: an integrative review

Chagasic infection among blood donors in Brazil: an integrative review

A sixty-four-year-old woman with Chagas' disease, who underwent implantation of a permanent cardiac pacemaker and evolved with rapidly progressive heart failure

The epidemiologic profile and prevalence of cardiopathy in Trypanosoma cruzi infected blood donor candidates, Londrina, Paraná, Brazil

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