Epidemiologia do consumo de medicamentos no primeiro trimestre de vida em centro urbanodo Sul do Brasil

Weiderpass, Elisabete; Béria, Jorge Umberto; Barros, Fernando C.; Victora, César G.; Tomasi, Elaine; Halpern, Ricardo

doi:10.1590/s0034-89101998000400005

Cited by 21 publications

(40 citation statements)

References 10 publications

(14 reference statements)

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“…28 In our study there was a reduction in the prevalence of medicine use over the three follow-up times, especially at 24 months. Similar results were found in a 2005 Italian study (Lombardia) reporting a prevalence of 65% among children from 12 months to fi ve years of age.…”

Section: Discussionsupporting

confidence: 46%

“…The same trend was observed in previous birth cohorts from Pelotas (1982 and, probably due to family's anxiety and concerns about the child's health. 9,28 Different variables directly or indirectly related to more severe health conditions (neonatal ICU care, hospitalization, low birthweight or gestational conditions), as well as the mother's perception of their child's health were associated to a higher prevalence of medicine use. These variables contribute to the understanding of the relations found as they all point to the same direction and are consistently associated.…”

Section: Discussionmentioning

confidence: 99%

“…Higher medicine use was also seen among children who were not breastfed. 28 Different factors related to family, community and health settings infl uence medicine use. At the family level, the perception of the need of medicines, conceptions about effi cacy (or lack thereof), prices and education level contribute to medicine use patterns.…”

Section: Introductionmentioning

confidence: 99%

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Factors associated to medicine use among children from the 2004 Pelotas Birth Cohort (Brazil)

Oliveira

Bertoldi

Domingues³

et al. 2012

Rev. Saúde Pública

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OBJECTIVE: To identify factors associated to medicine use among children from the 2004 Pelotas Birth Cohort, Brazil. METHODS: Prospective study to evaluate medicine use in children aged 3, 12 and 24 months regardless of the reasons, therapeutic indication or class. The study included 3,985 children followed up at three months of age, 3,907 at 12 months, and 3,868 at the last follow-up time of 24 months. Mothers were interviewed to collect information on medicine use during the recall period of 15 days prior to the interview. The outcome was studied according to sociodemographic and perinatal variables, mother's perception of child's health and breastfeeding status. Crude and adjusted analyses were performed by Poisson regression following a hierarchical model. RESULTS: The prevalence of medicine use ranged from 55% to 65% in the three follow-ups. After controlling for confounders, some variables remained associated to medicine use only at the three-month follow-up with greatest use among children of younger mothers, those children who had intrapartum complications, low birthweight, were never breastfed and were admitted to a hospital. Greatest medicine use was also associated with being a firstborn child at 3 and 12 months; mother's perception of their child health as fair or poor and children whose mothers have private health insurance at 12 and 24 months; highest maternal education level at all follow-up times. CONCLUSIONS: Different variables influence medicine use among children during the first two years of life and they change as the child ages especially maternal factors and those associated to the child's health problems.

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Section: Discussionsupporting

confidence: 46%

Section: Discussionmentioning

confidence: 99%

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Factors associated to medicine use among children from the 2004 Pelotas Birth Cohort (Brazil)

Oliveira

Bertoldi

Domingues³

et al. 2012

Rev. Saúde Pública

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“…Even so, continuous use at three months was 50% higher than that found in a prior cohort, in which uninterrupted use for one month or longer was found to occur in 20% of children. 26 This difference may be related to changes in prescription practices caused by changes in morbidity profi le, given the 11-year interval between the two cohorts. A survey carried out in the United States showed that prevalence of continuous medicine use among children increased between 2002 and 2005 for a number of different therapeutic classes, and that this trend may be related to increased risk factors for chronic diseases.…”

Section: Discussionmentioning

confidence: 99%

“…b By three months of age, 69% of children from the state of Rio Grande do Sul, Southern Brazil, used medicines, most frequently acetylsalicylic acid, benzalkonium chloride/saline, and dimethicone/homatropine; combinations of three or more medicines were used by 19% of children, and prevalence of chronic medicine use was as high as 20%. 26 Data from the National Toxic-pharmacological Information System (SINITOX) show that excessive medicine use at young ages is a reason for concern: medicine-related intoxications increased from 15% in 2000 to 29% in 2005, children under the age of fi ve years being the greatest victims (35% of cases). c In 2007, medications were the most frequent cause of intoxication in Brazil, with an average of more than 20 children intoxicated per day.…”

Section: Introductionmentioning

confidence: 99%

Uso de medicamentos do nascimento aos dois anos: Coorte de Nascimentos de Pelotas, RS, 2004

Oliveira

Bertoldi

Domingues³

et al. 2010

Rev. Saúde Pública

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OBJETIVO: Descrever a utilização de medicamentos em crianças aos três, 12 e 24 meses de idade. MÉTODOS: Estudo transversal utilizando dados da Coorte de Nascimentos de Pelotas, RS, de 2004. Foram incluídas 3.985 crianças aos três meses, 3.907 aos 12 meses e 3.868 aos 24 meses de idade. O desfecho considerado foi o uso de medicamentos pelas crianças nos 15 dias anteriores à entrevista. Informações sobre as variáveis independentes (medicamentos utilizados, fonte de indicação, forma de aquisição, regularidade do uso e grupos terapêuticos) foram coletadas por meio de questionário padronizado, em entrevista aos pais nos domicílios. RESULTADOS: As prevalências de uso de medicamentos aos três, 12 e 24 meses foram de 65,0% (IC 95%: 63,5;66,5), 64,4% (IC 95%: 62,9;65,9) e 54,7% (IC 95%: 53,1;56,2), respectivamente. Com o avanço da idade observou-se diminuição no número total de medicamentos utilizados e aumento na automedicação, essa última chegando a 34% aos 24 meses. Também, a freqüência do uso de medicamentos em caráter eventual aumentou e diminuiu a de uso contínuo. Os medicamentos foram adquiridos principalmente com recursos próprios e cerca de 10% foi adquirido pelo Sistema Único de Saúde. Observou-se mudança no perfil dos grupos terapêuticos mais utilizados em função da idade. Aos três meses, o maior uso foi de medicamentos dermatológicos (36%); aos 12 meses, de medicamentos para o sistema respiratório (24%); e, aos 24 meses, de analgésicos (26%). Comparando-se o uso aos 24 meses com o dos três meses de idade observou-se diminuição na utilização de: medicamentos destinados ao trato alimentar e metabolismo, aos órgãos dos sentidos, sistema cardiovascular e produtos dermatológicos. Houve aumento na utilização de: medicamentos anti-infecciosos sistêmicos, destinados ao sistema musculoesquelético, ao sistema respiratório, analgésicos, antiparasitários, inseticidas e repelentes. CONCLUSÕES: A utilização de medicamentos nesta coorte foi elevada e remete à necessidade de priorização do uso racional de medicamentos nos primeiros anos de vida.

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Cohort Profile: The 1993 Pelotas (Brazil) Birth Cohort Study

Victora

Hallal

Araújo

et al. 2007

International Journal of Epidemiology

210

187

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Epidemiologia do consumo de medicamentos no primeiro trimestre de vida em centro urbanodo Sul do Brasil

Cited by 21 publications

References 10 publications

Factors associated to medicine use among children from the 2004 Pelotas Birth Cohort (Brazil)

Factors associated to medicine use among children from the 2004 Pelotas Birth Cohort (Brazil)

Uso de medicamentos do nascimento aos dois anos: Coorte de Nascimentos de Pelotas, RS, 2004

Cohort Profile: The 1993 Pelotas (Brazil) Birth Cohort Study

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