Introduction: Among the various areas, approaches and themes that compose the Public Health, Health Promotion was established as one of the most established which indicates the relevance of reflection on their production. And among the lines of research in the area of Health Promotion, in recent years has highlighted the topic of Social Determinants of Health, this concern expressed by this line of research and action on the Social Determinants of Health (SDH) as well as proposals for health promotion necessarily refer to a reflection on the social dynamics as they are geared towards the transformation of living conditions. Objective: This study aimed to identify the production of research in SDH at the School of Public Health, University of São Paulo in the period 2004 to 2008, and point out areas of interest and trends of this field of study. Methodology: The methodology involved a literature review of studies in SDH. Data collection was based on consultation with the following databases: BVS (Virtual Library in Health), SciELO (Scientific Electronic Library Online) and CAPES thesis database. The indices for the study were selected according to the Health Sciences Descriptors (DeCS). Results: Among the many social determinants of health found during the data collection, the most cited were: social inclusion, security, social justice, transportation, quality of life, models of health care, education, leisure, work environment, fairness and distribution in income, resources sustainable, healthy ecosystem, stress and sanitation. It was given preference for results that are reported directly to the research theme on Social Determinants of Health, these results were sorted by year, type of publication: theses, dissertations, journal articles and for classification of social determinants of health. Conclusion: It was found that the scientific production with the Social Determinants of Health in the School of Public Health-USP has grown steadily in recent years and that most work is directed toward the study of inequities in health, followed by studies on the empowerment and quality of life.