Avaliação da concentração de ferro orgânico em uma população de grávidas

Abstract

Objetivou-se conhecer as alterações da concentração de hemoglobina (Hb), hematócrito (Ht), ferro sérico (FS), capacidade total de ligação de ferro (CTLF) e saturação de transferrina (ST) durante a gestação normal em mulheres não anêmicas (H > 11,0g/dl). Verificou-se, entre as 250 mulheres selecionadas, diminuição dos valores de Hb e Ht até o 7.° mês de gravidez quando houve aumento nesses valores até o final do processo gravídico; o mesmo foi observado com relação aos valores do FS. A CTLF apresentou um aumento durante todo o período considerado enquanto a ST diminuiu. Os resultados observados justificam o uso de suplementação de ferro como uma estratégia de saúde pública a ser utilizada no controle da deficiência de ferro, mesmo entre mulheres não anêmicas.

Anemia em gestantes brasileiras antes e após a fortificação das farinhas com ferro

“…5 Such a difference may be related to supplementation, since our subjects had not yet been given iron sulfate supplementation at the time of Hb testing. The fi nding that the curve in our sample followed the reference by Szarfarc et al 21 after the third month of pregnancy corroborates the previous hypothesis, since the latter curve was built on data obtained from Brazilian pregnant women not under iron supplementation. This reiterates the importance of pharmacological supplementation for the maintenance of normal Hb levels.…”

“…Taking into account the diffi culty in diagnosing anemia during pregnancy due to hemodilution, 20 Hb values were evaluated according to gestational age, based on two different curves, published by the Centers for Disease Control and Prevention (CDC) 5 and by Szarfarc et al 21 The reason for using two references was the fact that the CDC curve 5 is constructed based on European studies of pregnant women who received iron supplementation, which allows for comparisons of our data with those of other studies in the international literature, while the curve by Szarfarc et al 21 is constructed based on data obtained from healthy but non-supplemented Brazilian pregnant women, and thus represents a setting closer to that of our sample.…”

Anemia e deficiência de ferro em gestantes adolescentes

“…Essa tendência de queda reitera achados anteriores (Svanberg et al, 1975;Romslo et al, 1983;Szarfarc et al, 1983;Guerra et al, 1992;Fujimori et al, 1999) e permite supor que à medida que a gestação avança, a liberação de ferro para a eritropoese medular se torna mais severamente comprometida.…”

Hemoglobin curves during pregnancy before and after fortification of flours with iron

“…It was compared to the Centers for Diseases Control and Prevention (CDC) curve (13) , which propose specific cut-off (5 th percentile) per gestational month for pregnant women supplemented with iron; and it was also compared to the Hb distribution model found in Szarfarc et al (14)(15) studies with Brazilian pregnant women not supplemented with iron, using the 7 th percentile to establish risk. Through a cubic polynomial regression model (Table 2), the Hb adjusted curve was estimated by gestational month (Figure 1).…”