Quantificação do indicador de Nelson de Moraes (curva de mortalidade proporcional)

Guedes, José da Silva; Guedes, Marilda Lauretti da Silva

doi:10.1590/s0034-89101973000200004

Cited by 9 publications

(4 citation statements)

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“…Patient age was described and analyzed as a continuous variable. Patient age was stratified into four age groups in accordance with WHO guidelines [35]. In this study, platelet count, to identify thrombocytopenia, was stratified into severe (< 50,000 platelets/μL) and moderate (between 50,000 and 150,000 platelets/μL), as previously described [15, 36].…”

Section: Methodsmentioning

confidence: 99%

Aspartate aminotransferase-to-platelet ratio index (APRI): A potential marker for diagnosis in patients at risk of severe malaria caused by Plasmodium vivax

et al. 2019

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Acute infection with Plasmodium vivax, classically associated with benign disease, has been presenting as serious and even fatal disease in recent years. Severe disease is mainly due to biochemical and hematological alterations during the acute phase of infection. In the present cross-sectional study, the aspartate aminotransferase-to-platelet ratio index (APRI) was evaluated as a method for identifying patients at risk of severe vivax malaria. This retrospective study included 130 patients with confirmed P. vivax infection between June 2006 and January 2018. Clinical-epidemiological data were obtained from medical records. Hematological and biochemical parameters were determined using automated equipment. The criteria of severity for infection by Plasmodium falciparum, established by the World Health Organization (WHO), were adapted to classify patients with danger signs of severe vivax malaria. Of the 130 patient’s records evaluated, 19 (14.6%) had one or more signs and symptoms of severe malaria. The mean APRI values among patients with and without severe malaria were 2.11 and 1.09, respectively (p = 0.044). Among those with severe disease, the proportion with an APRI value above 1.50 was 30% compared to the 10% among those without severe disease (p = 0.007). The area under the receiver operating characteristic curve (95% CI), calculated to assess the accuracy of the APRI in discriminating between patients with and without severe disease, was 0.645 (0.494; 0.795). An APRI cutoff of 0.74 resulted in sensitivity of 74.0%, specificity of 56.0%, and accuracy of 65.0%. This study shows that the APRI is elevated in patients with evidence of infection by P. vivax. Based on the good sensitivity found in this study, we conclude that this simple index can serve as a diagnostic biomarker to identify patients at risk of severe disease during the acute phase of P. vivax infection.

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Section: Methodsmentioning

confidence: 99%

Aspartate aminotransferase-to-platelet ratio index (APRI): A potential marker for diagnosis in patients at risk of severe malaria caused by Plasmodium vivax

et al. 2019

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“…To complement, years later, the Nelson de Moraes Curve was created, which provides a graphical representation of proportional mortality data for all causes and age groups to assess the health level of a region 9 .…”

Section: Introductionmentioning

confidence: 99%

Epidemiological profile of acute myocardial infarction in Brazil between 2009 and 2019

Ferreira¹,

Moraes²

2023

Ii International Seven Multidisciplinary Congress

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Acute myocardial infarction (AMI) is the syndrome with classical clinical manifestations, laboratory evidence of necrosis by ischemia of the heart muscle, and characteristic changes in electrocardiogram (ECG). AMI can be classified into several types according to electrocardiographic, pathophysiological, clinical, prognostic and etiological criteria, which is valid because it allows specific and more assertive interventions to be performed

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“…Since the 1950s, the Swaroop-Uemura index has been used to measure the levels of health care in certain demographic regions. To complement it, the Nelson de Moraes Curve was created, a graphical representation of proportional mortality in various age groups 23 . In the period from 2010 to 2020, Brazil showed an excellent level of health care, considering the Swaroop-Uemura index of 77.77% and the Nelson de Moraes Curve type IV, as shown in figure 1 24 .…”

Section: Introductionmentioning

confidence: 99%

Hospital morbidity and mortality profile due to pneumonia in Brazil between 2010 and 2020

Marangoni¹

2023

Ii International Seven Multidisciplinary Congress

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Quantificação do indicador de Nelson de Moraes (curva de mortalidade proporcional)

Abstract: mortalidade proporcional). Rev. Saúde públ., S. Paulo, 7:103-13, 1973

Cited by 9 publications

References 0 publications

Aspartate aminotransferase-to-platelet ratio index (APRI): A potential marker for diagnosis in patients at risk of severe malaria caused by Plasmodium vivax

Aspartate aminotransferase-to-platelet ratio index (APRI): A potential marker for diagnosis in patients at risk of severe malaria caused by Plasmodium vivax

Epidemiological profile of acute myocardial infarction in Brazil between 2009 and 2019

Hospital morbidity and mortality profile due to pneumonia in Brazil between 2010 and 2020

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