Uso de dexmedetomidina em pacientes obesos mórbidos submetidos a gastroplastia: estabilidade cardiovascular e consumo de anestésicos venosos. Estudo retrospectivo

Abstract

This study has shown the efficacy of dexmedetomidine administration in combination with venous anesthesia with propofol and alfentanil, thus promoting reduction in venous anesthetic drugs consumption, cardiovascular stability and time to recovery similar to that of the technique without dexmedetomidine. No side effects were noted associated with the use of dexmedetomidine.

Effects of dexmedetomidine on surgical site wound pain in patients undergoing laparoscopic cholecystectomy: A meta‐analysis

“…When opioids, such as fentanyl, are used as adjuncts to epidural anaesthesia, they can effectively help in reducing the amount of local anaesthetic drugs and produce good analgesia; however, they may also cause side effects, such as nausea and vomiting, skin itching, and urinary retention, which may affect patient's recovery 7,8 . Dexmedetomidine is a highly selective and effective alpha‐2 agonist that acts mainly on the central and peripheral alpha‐2 receptors and has extensive effects on the brain, including sedation, analgesia, and anxiolytic effects 9 . In addition, dexmedetomidine exerts neuroprotective effects 10 .…”