Estudo comparativo entre bupivacaína racêmica a 0,25% e bupivacaína com excesso enantiomérico de 50% (S75-R25) a 0,25%, associadas ao fentanil para analgesia de parto com deambulação da parturiente

Abstract

Both racemic and S75-R25 0.25% bupivacaine associated to fentanyl were effective for labor analgesia.

A Randomised Controlled Trial to Evaluate the Effectiveness of Intrathecal Bupivacaine Combined with Different Adjuvants (Fentanyl, Clonidine and Dexmedetomidine) in Caesarean Section

“…Spinal anesthesia performed with fine gauge disposable needles and administration of bupivacaine combined with adjuvant drugs into the subarachnoid space, is reported as effective technique in most caesarean sections [20][21][22]. Previous studies have indicated that administration of epidural bupivacaine in labor analgesia is an advantage because it is coupled with lower intensity of motor blockade [23,24] besides preserving the differential blockade of racemic bupivacaine [25][26][27][28]. The aim of this perspective, double blind randomized study was to evaluate and compare the effectiveness of bupivacaine-fentanyl, bupivacaineclonidine and bupivacaine-dexmetomodine on the quality of blockade and maternal and neonatal repercussions.…”

Estudo comparativo entre bupivacaína (S75-R25) e ropivacaína em bloqueio peridural para analgesia de parto

“…Those authors observed that pain intensity during the evolution of labor was similar between groups, except at 45 minutes, when patients on 0.25% bupivacaine (S75-R25) presented lower pain scores 11 .…”

“…The literature has demonstrated that the administration of epidural bupivacaine (S75-R25) is associated with lower intensity of motor blockade 8,9 , besides preserving the differential blockade of racemic bupivacaine, representing an advantage of its use in labor analgesia 10,11,12,13 . Parturientss who participated in this study received 0.25% bupivacaine (S75-R25) and 0.20% ropivacaine.…”