Adaptação e validação do Pediatric Asthma Quality of Life Questionnaire (PAQLQ-A) em crianças e adolescentes brasileiros com asma

Abstract

Objectives: To translate the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) into Portuguese and adapt it to the Brazilian context, for use in children and adolescents with asthma and to validate the adapted version of the questionnaire (PAQLQ-A). Methods: Children and adolescents (7 to 17 years old) with asthma answered the PAQLQ-A on admission and were assessed using a clinical severity score. According to this score, patients were classified as mild (< 2) or moderate/severe (> 2). They were reassessed on at least two occasions at an interval of 2 to 4 weeks. Furthermore, patients in whom asthma was properly controlled were classified as stable, and those in whom it could not be controlled, as unstable. Results: The reproducibility of the PAQLQ-A was evaluated in stable patients by comparing the mean domain scores: symptoms, emotions, activities, and the overall clinical severity score on two predefined occasions with an interval of 15 to 30 days in between. Responsiveness was evaluated among unstable patients. The mean domain scores and the overall score were different on both occasions, and so was the clinical severity score. The validity of the questionnaire was determined by the application of Cronbachs alpha reliability coefficient (α = 0.909). Conclusions: The translation of the PAQLQ into Portuguese did not modify the framework of the original questionnaire; the PAQLQ-A is easy to use, with easy reproducibility, constituting a valuable instrument for the evaluation of the quality of life in children and adolescents with asthma.

Quality of life of asthmatic adolescents: assessment of asthma severity, comorbidity, and life style

“…Sua validação para o português (do Brasil) foi feita por La Scala et al 17 , sendo, o questionário, construído para ser aplicado em crianças entre 7 e 17 anos mediante entrevistas face a face ou por autopreenchimento com duração média de 10 minutos. As opções de resposta para cada item foram classificadas em uma escala de 7 pontos, onde 1 indica o máximo prejuízo e 7, nenhum prejuízo.…”

“…Na análise multivariada, embora o modelo tradicional de regressão logística seja frequentemente utilizado em estudos de prevalência, neste estudo optou-se pelo modelo de regressão log-binomial 17,18 , uma vez que este é capaz de estimar diretamente a RP. O modelo de regressão logística estima razão de chances (odds ratio, OR), superestimando a RP quando a prevalência do desfecho é relativamente alta na população estudada, como é no nosso caso.…”

“…Schimer et al 29 sugerem que existe uma grande relação entre QV em saúde e gravidade da doença, fatores sociodemográficos e tratamento. Para La Scala et al 17 , a asma afeta a QV como um todo e tem grande influência na saúde física e funcional.…”

Qualidade de vida em adolescentes asmáticos: avaliação da gravidade da asma, comorbidade e estilo de vida

“…In the multivariate analysis, although the traditional logistic regression model is often used in prevalence studies, in the present study, we decided to use the log-binomial regression model, 17,18 since this model is able to directly estimate PR. The logistic regression model estimates the odds ratio (OR), overestimating the PR when the outcome prevalence is quite high in the population of the study, as it was the case in the present study.…”

“…15,16 This instrument has 23 items and three domains (symptoms, activity limitation, and emotional function) and it is able to quantify changes in the QoL of individuals throughout time. Its validation for Brazilian Portuguese was carried out by La Scala et al, 17 and the questionnaire was designed to be administered to children between 7 and 17 years old by means of face-to-face interviews or to be completed by the subjects during an average period of 10 minutes. The answer options for each item were …”