EEG alpha peak frequency analysis during memorizing of figures in patients with mild cognitive impairment

Abstract

-Objective: To investigate spectral analysis of electroencephalograms (EEG) for the alpha frequency band during rest and cognitive stimulation in healthy adults and individuals with mild cognitive impairment. Method: We analyzed 56 EEGs from 28 patients, 7 men and 21 women, 12 of whom (40%) were controls, 16 patients with mild cognitive impairment (60%). Ages ranged from 61 to 83 years. All individuals were patients in the Psycho-geriatric Out-patients Clinic of LIM-27, of the Psychiatric Institute of the Clinicas Hospital of the Faculty of Medicine of the University of São Paulo, IPq-HCFMUSP, between 2004 and 2007. Each patient underwent two exams with an interval of at least six months between them. During the exam, performed after a period of wakefulness and rest, the patients memorized series of pictures. Results: Analysis of spectral potential both at rest and during the memorizing task showed no statistical differences between baseline and final recordings. Conclusion: Spectral analysis of EEGs showed coherent results with the clinical stability of the patients evaluated but was unable to distinguish between the control group and patients with MCI. Future studies should include a larger sample and a longer follow up. Over the last few years, different quantification techniques using the EEG have proven useful in the study of cognitive processes 1 . According to the "Recommendations for the recording/interpretation of topographical mapping of the EEG" by the Brazilian Society of Clinical Neurophysiology the EEG has, by and large, long been in routine use and is well established as an aid in the evaluation of dementias and encephalopathies, especially when

The Design of Cognitive Training Games for the Thai Elderly

“…Various studies show that cognitive training games promote working memory [11][12][13][14][15][16][17][18][19][20][21][22][23]. Schweizer et al [11] investigated whether brain training can improve cognitive function and the control of emotional material.…”

Memorization Test and Resting State EEG Components in Mild and Subjective Cognitive Impairment

“…Some studies have tried to investigate EEG alterations in MCI due to AD [15], [18]- [24] and few studies considered patients with Subjective Cognitive Impairment (SCI) [25], [26]. Most of those studies were based on resting EEG recordings, not during cognitive stimulation, while spectral analysis of EEGs recorded during a memorization task was unable to distinguish between MCI patients and control group [27].…”