Urinary symptoms in Parkinson's disease: prevalence and associated factors

Abstract

-----The authors present a cross-sectional study involving 61 patients with idiopathic Parkinson's disease (PD) who were consecutively examined and compared to a control group with 74 subjects. Only patients who fulfilled the standard diagnostic criteria for PD and whose brain magnetic resonance imaging was normal were included. The objective of the study was to evaluate the prevalence of inferior urinary tract symptoms in PD and to study the possible association between clinical factors to urinary dysfunction. ln the patient group, 39.3% presented urinary symptoms when compared to 10.8% in the control group. All symptomatic patients presented irritative symptoms. The most common irritative symptom PD was nocturia, followed by frequency and urinary incontinence. Around 25% of the patients presented functional obstructive symptoms determined by the disease. The most frequent obstructive symptom was incomplete emptying of the bladder. Only the age of the patients and control group were correlated with urinary dysfunction.KEY WORDS: Parkinson's disease, urinary symptoms, autonomic symptoms.Prevalência e fatores associados aos sintomas urinários na doença de P Prevalência e fatores associados aos sintomas urinários na doença de P Prevalência e fatores associados aos sintomas urinários na doença de P Prevalência e fatores associados aos sintomas urinários na doença de P Prevalência e fatores associados aos sintomas urinários na doença

Is there a difference between Parkinson disease patients and a control group in terms of urinary symptoms and quality of life?

“…In a study comparing total irritative and obstructive common urinary scores between the sexes in PD by Campos-Sousa et al, they reported no differences between the sexes (14). Similarly, in our study, there were no differences identified between (14)(15)(16).…”

“…In a study comparing total irritative and obstructive common urinary scores between the sexes in PD by Campos-Sousa et al, they reported no differences between the sexes (14). Similarly, in our study, there were no differences identified between (14)(15)(16). The lack of differences identified between women and elderly men, who are expected to have more urological complaints linked to prostate growth, is reported to be due to the contribution of neurological changes occurring in PD to urinary complaints (17,18).…”

Role of the Anterior Cingulate Cortex in the Control of Micturition Reflex in a Rat Model of Parkinson's Disease

“…In patients with PD, the prevalence of lower urinary tract symptoms (LUTS) identified by validated questionnaires is around 30% 3,4 . Previous urodynamic studies of PD patients with LUTS have revealed that the most frequent abnormality is detrusor overactivity, resulting in nocturia, urinary urgency and frequency and urge incontinence , 5,6 .…”

Urinary dysfunction in Parkinson’s disease

“…Распространенность нарушений моче-испускания у больных с ИБП оценивают в весьма широком диапазоне -от 20 до 77 % [7][8][9][10][11]. Ряд авторов указывают, что данные о частоте нару-шений мочеиспускания при ИБП зачастую завы-шены, поскольку исследования были проведены либо до выделения других заболеваний, сопрово-ждающихся синдромом паркинсонизма (например, мультисистемной атрофии) в отдельные нозологи-ческие единицы, либо в исследование включали также пациентов с другими формами паркинсониз-ма (например, сосудистый паркинсонизм) [12,13]. По данным этих исследователей распространен-ность нарушений мочеиспусканий при ИБП состав-ляет от 27 до 39 %.…”