Ganglioglioma desmoplásico da infância: estudo clínico, histopatológico e epidemiológico de cinco casos

Torres, Luíz Fernando Bleggi; Filho, Jorge Sérgio Reis; Netto, Mário Rodrigues Montemór; Noronha, Lúcia de; Aléssio, Alessandra Beatriz; Neto, Arnolfo de Carvalho

doi:10.1590/s0004-282x1998000300014

Cited by 7 publications

(1 citation statement)

References 8 publications

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“…Desmoplastic infantile gangliogliomas (DIG) are rare supratentorial tumors that account for 0.1-1% of childhood central nervous system (CNS) tumors [1,2]. DIG, along with desmoplastic infantile astrocytoma (DIA), is classified as a desmoplastic CNS neoplasm and has been categorized as grade I by the World Health Organization (WHO), indicating a benign tumor behavior [3,4]. Both tumors exhibit poorly differentiated cells.…”

Section: Introductionmentioning

confidence: 99%

MRI Findings of Desmoplastic Infantile Ganglioglioma: A Case Report and Analysis

Dias,

Camargo

et al. 2023

Cureus

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Desmoplastic infantile gangliogliomas (DIG) are rare intracranial tumors that predominantly affect children. They are characterized by a mixture of glial and neuronal components interspersed with abundant fibrous stroma and are typically located on the surface of the cerebral hemispheres. In this case report, we present a seven-year-old male child with a late presentation of DIG, which is typically diagnosed between zero and 60 months of age. We discuss the MRI findings, clinical symptoms, and differential diagnosis of DIG in patients with this central nervous system tumor.

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Section: Introductionmentioning

confidence: 99%

MRI Findings of Desmoplastic Infantile Ganglioglioma: A Case Report and Analysis

Dias,

Camargo

et al. 2023

Cureus

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A report of a desmoplastic non-infantile ganglioglioma in a 6-year-old boy with review of the literature

et al. 2009

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Desmoplastic infantile gangliogliomas (DIG) are uncommon supratentorial brain tumors with a usually good prognosis despite an aggressive radiological appearance that typically occurs in infants below the age of 24 months. DIGs are exclusively supratentorial, generally have a voluminous size, and are partially cystic. Total surgical removal is sufficient for the treatment of these tumors, and no chemotherapy or radiotherapy is indicated if complete resection is achieved. Except for age difference, DIG and desmoplastic non-infantile gangliogliomas are radiologically and histologically similar. Non-infantile variants of this biologically benign intracranial neoplasm are rare; only 15 cases of non-infantile DIGs have been reported in the literature. As far as we know, this case is the 16th in literature. We reported the magnetic resonance imaging and histological findings of desmoplastic ganglioglioma in a 6-year-old boy.

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Desmoplastic infantile and non-infantile ganglioglioma. Review of the literature

2011

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Desmoplastic gangliogliomas (DIG) are rare primary neoplasms that comprise 0.5-1.0% of all intracranial tumors. Clinically, there are two forms of DIG, the infantile and the non-infantile. These tumors invariably arise in the supratentorial region and commonly involve more than one lobe, preferentially the temporal and frontal. On neuroimaging are seen as large hypodense cystic masses with a solid isodense or slightly hyperdense superficial portion. The histologic diagnosis is characterized by the presence of three different cell lines: astrocytic, neuronal, and primitive neuroectodermal marker sites, which were demonstrable. The treatment of choice is radical surgical excision, and if this is done, achieved complete healing of the patient does not require additional treatment. A literature review of DIG was compiled through Medline/Ovid using the keywords "desmoplastic infantile ganglioglioma", "desmoplastic non-infantile ganglioglioma" covering the years 1984-2009. We present a review of a total of 113 cases of infantile (94) and non-infantile gangliogliomas (19) published to date, examining the clinical, radiologic, surgical, and pathological aspects, as well as the outcome. Desmoplastic gangliogliomas represent a rare tumor group with two well-defined age groups, the children and non-children. Desmoplastic infantile gangliogliomas are the most common and occur in children below 5 years of age, and the large majority of them present within the first year of life. Surgery is the treatment of choice and no complementary treatment is needed in cases of complete tumor resection.

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Ganglioglioma desmoplásico da infância: estudo clínico, histopatológico e epidemiológico de cinco casos

Cited by 7 publications

References 8 publications

MRI Findings of Desmoplastic Infantile Ganglioglioma: A Case Report and Analysis

MRI Findings of Desmoplastic Infantile Ganglioglioma: A Case Report and Analysis

A report of a desmoplastic non-infantile ganglioglioma in a 6-year-old boy with review of the literature

Desmoplastic infantile and non-infantile ganglioglioma. Review of the literature

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