Abstract:It has long been known that the cerebrospinal fluid can not be the nervous system lymph, and Mestrezat, in his authoritative book of the year 1912, demonstrated it plainly. Davson has undertaken this subject and suggested the hypothesis of a sink action of cerebrospinal fluid, allowing a slow leakage of solutes from nervous tissue extracellular space. In order to test this hypothesis, Oldendorf and Davson performed a series of animal experiments and they demonstrated that there was leakage of the solute into c… Show more
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