Preoperative Risk Factors for Acute Kidney Injury After Liver Transplantation: Results From a Cross-Sectional Study in Northeast of Brazil

Junior, Raimundo Martins Gomes; Cezar, Lia Cavalcante; Meneses, Gdayllon Cavalcante; Silva, Geraldo Bezerra da; Garcia, José Huygenes Parente; Daher, Elizabeth De Francesco

doi:10.1590/s0004-2803.201800000-03

Cited by 7 publications

(6 citation statements)

References 16 publications

(20 reference statements)

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“…As expected, the severity of liver disease was associated with AKI after OLT (13,21), as assessed by the Child-Pugh score and MELD/MELD-Na score in our research. Due to the significant overlap existed between the etiologies of liver and kidney diseases (22), some factors that caused liver disease could cause simultaneous damage to kidney, such as autoimmune disease, various drugs and toxins, and hepatitis C virus, etc.…”

Section: Discussionsupporting

confidence: 86%

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A prediction score model and survival analysis of acute kidney injury following orthotopic liver transplantation in adults

Bao

Wang

et al. 2021

Ann Palliat Med

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Background: Acute kidney injury (AKI) is one of the postoperative complications following orthotopic liver transplantation (OLT), and is related to the high morbidity and mortality. Although there were numerous propensity factors for AKI, their cumulative influence remains unclear. Our aims were to develop a score model to predict postoperative AKI and to evaluate the impact of AKI on the recipients' long-term survival.

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Section: Discussionsupporting

confidence: 86%

“…Other researches also believed that the MELD score was defective in predicting the development of AKI (7,12). For this reason, researchers such as Sujan et al tried to take the MELD/ MELD-Na score or the Child-Pugh score into the AKI prediction model, and achieved good performance (8,13,21).…”

Section: Discussionmentioning

confidence: 99%

A prediction score model and survival analysis of acute kidney injury following orthotopic liver transplantation in adults

Bao

Wang

et al. 2021

Ann Palliat Med

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“…К независимым и достоверным (p < 0,05) факторам риска развития ОПП относят также высокий уровень предоперационного креатинина в плазме крови и длительный период лечения дофамином [20]. Острое повреждение почек ассоциируют с высоким индексом массы тела, низким объемом выделяемой мочи [29], низким уровнем сывороточного альбумина и повышенным уровнем прямого билирубина, щелочной фосфатазы и гамма-глутамилтрансферазы [41].…”

Section: дооперационные факторы риска у реципиентаunclassified

New trends in the study of post-transplant acute kidney injury after liver transplantation

Ильинский

Цирульникова

2020

RJTAO

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Acute kidney injury (AKI) after liver transplantation (LT) is a pressing issue and remains the focus of many researchers. The etiology of AKI is multifactorial, but the main one is ischemia-reperfusion injury to the liver transplant. Numerous preoperative, intraoperative and postoperative risk factors contribute to the development of AKI. The use of standard classifications, such as AKIN, RIFLE and KDIGO, has improved post-transplant AKI diagnosis. However, determination of creatinine levels in the blood enables AKI diagnosis only in the later stages of this syndrome. Therefore, studies are currently underway to find ways of early diagnosis of AKI using biomarkers. Transition to a molecular level not only improves accuracy but also facilitates early diagnosis of AKI. Currently, the diagnostic capabilities of neutrophil gelatinase-associated lipocalin (NGAL) are the most investigated. To date, there are no known measures of preventing post-transplant AKI. Moreover, treatment of this condition cannot be considered satisfactory. Even a mild post-transplant AKI can be fatal. In severe AKI, where renal replacement therapy is used, there is a risk of death in the intensive care unit. More than half of AKI patients develop chronic kidney disease requiring chronic hemodialysis.

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“…There are many factors that affect surgical treatment. The main factor is whether the positioning of the internal mouth is accurate before surgery [ 8 , 9 ], and the symptomatic degree of the surgical plan will affect the probability of recurrence and the degree of anal function retention [ 10 , 11 ]. The complex anal fistula is mainly treated by the surgery, with traditional Chinese medicine used for adjuvant treatment.…”

Section: Introductionmentioning

confidence: 99%

Deep Learning-Based CT Image Characteristics and Postoperative Anal Function Restoration for Patients with Complex Anal Fistula

Han

Chen

Cheng

et al. 2021

Journal of Healthcare Engineering

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Objective. This study aimed to optimize the CT images of anal fistula patients using a convolutional neural network (CNN) algorithm to investigate the anal function recovery. Methods. 57 patients with complex anal fistulas admitted to our hospital from January 2020 to February 2021 were selected as research subjects. Of them, CT images of 34 cases were processed using the deep learning neural network, defined as the experimental group, and the remaining unprocessed 23 cases were in the control group. Whether to process CT images depended on the patient’s own wish. The imaging results were compared with the results observed during the surgery. Results. It was found that, in the experimental group, the images were clearer, with DSC = 0.89, precision = 0.98, and recall = 0.87, indicating that the processing effects were good; that the CT imaging results in the experimental group were more consistent with those observed during the surgery, and the difference was notable ( P < 0.05 ). Furthermore, the experimental group had lower RP (mmHg), AMCP (mmHg) scores, and postoperative recurrence rate, with notable differences noted ( P < 0.05 ). Conclusion. CT images processed by deep learning are clearer, leading to higher accuracy of preoperative diagnosis, which is suggested in clinics.

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Preoperative Risk Factors for Acute Kidney Injury After Liver Transplantation: Results From a Cross-Sectional Study in Northeast of Brazil

Abstract: Low levels of serum albumin, and elevated levels of DB, AP and GGT in the preoperative period are risk factors for AKI development after liver transplantation.

Cited by 7 publications

References 16 publications

A prediction score model and survival analysis of acute kidney injury following orthotopic liver transplantation in adults

A prediction score model and survival analysis of acute kidney injury following orthotopic liver transplantation in adults

New trends in the study of post-transplant acute kidney injury after liver transplantation

Deep Learning-Based CT Image Characteristics and Postoperative Anal Function Restoration for Patients with Complex Anal Fistula

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