New comparative clinical and biometric findings between acute primary angle-closure and glaucomatous eyes with narrow angle

Mérula, Rafael Vidal; Cronemberger, Sebastião; Diniz-Filho, Alberto; Calixto, Nassim

doi:10.1590/s0004-27492010000600009

Cited by 5 publications

(4 citation statements)

References 21 publications

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“…In one study of 37 eyes with malignant glaucoma, the mean axial length was 21.7 mm. (30) This value is equal or closer to those found in two studies of eyes with acute primary angle-closure (21.7 mm and 21.5 mm) and lower than that found in eyes with open-angle glaucoma (23.1 mm) (32,33) . The axial length of 21.7 mm (30) was exactly equal to that found in eyes with plateau iris configuration (34) .…”

Section: Ultrasonic Biometrysupporting

confidence: 50%

Malignant glaucoma

Cronemberger¹,

Calixto²,

Diniz-Filho³

2012

Rev. bras.oftalmol.

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RESUMOO objetivo deste artigo de revisão é discutir o conhecimento atual sobre a fisiopatologia e as abordagens diagnóstica, terapêutica e profilática do glaucoma maligno. Este tipo de glaucoma pode ocorrer após diferentes procedimentos cirúrgicos. Pode ocorrer em olhos áfacos, fácicos e pseudofácicos e se desenvolver espontaneamente em olhos não-operados, ou associado ao uso de mióticos. Atualmente, a biomicroscopia ultrassônica tem revelado muitos achados úteis e importantes para o diagnóstico e o tratamento do glaucoma maligno. Ele ocorre com maior frequência em olhos pequenos nos quais as medidas pré-operatórias da profundidade da câmara anterior e do comprimento axial são extremamente importantes para a sua profilaxia e diagnóstico.Descritores: Glaucoma; Glaucoma de ângulo fechado /diagnóstico; Glaucoma de ângulo fechado /classificação; Glaucoma de ângulo fechado /fisiopatologia; Glaucoma de ângulo fechado/terapia; Glaucoma de ângulo fechado/cirurgia; Glaucoma de ângulo fechado/ultrasonografia; Profilaxia

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Section: Ultrasonic Biometrysupporting

confidence: 50%

Malignant glaucoma

Cronemberger¹,

Calixto²,

Diniz-Filho³

2012

Rev. bras.oftalmol.

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“…Hence, if the lens thickness values are assessed earlier in the disease process, appropriate intervention can be planned. 2,8 Thus, lens thickness showed a direct correlation with shallowing of the anterior chamber by determining the LT/ ACD ratio. 4,5,7,9 Cataract surgery has been found to be a more effective treatment for an attack of acute primary angle closure (APAC) than laser iridotomy.…”

Section: Discussionmentioning

confidence: 94%

Assessment of Lens Thickness in Angle Closure Disease

Khayoom¹,

Mithrananda²

2016

jebmh

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BACKGROUND Anterior chamber depth and lens thickness have been considered as important biometric determinants in primary angle-closure glaucoma. Patients with primary narrow angle may be classified as a primary angle closure suspect (PACS), or as having primary angle closure (PAC) or primary angle closure glaucoma (PACG). 23.9% of patients with primary angle closure disease are in India, which highlights the importance of understanding the disease, its natural history, and its underlying pathophysiology, so that we may try to establish effective methods of treatment and preventative measures to delay, or even arrest, disease progression, thereby reducing visual morbidity. AIM To determine the lens thickness using A-scan biometry and its significance in various stages of angle closure disease. MATERIALS AND METHODS Patients attending outpatient department at Minto Ophthalmic Hospital between October 2013 to May 2015 were screened for angle closure disease and subsequently evaluated at glaucoma department. In our study, lens thickness showed a direct correlation with shallowing of the anterior chamber by determining the LT/ ACD ratio. A decrease in anterior chamber depth is proportional to the narrowing of the angle which contributes to the progression of the angle closure disease from just apposition to occlusion enhancing the risk for optic nerve damage and visual field loss. Hence, if the lens thickness values are assessed earlier in the disease process, appropriate intervention can be planned. CONCLUSION Determination of lens changes along with anterior chamber depth and axial length morphometrically can aid in early detection of angle closure. The role of lens extraction for PACG is a subject of increased interest. Lens extraction promotes the benefits of anatomical opening of the angle, IOP reduction and improved vision. This potential intervention may be one among the armamentarium of approaches for PACG. Among the current treatment modalities like laser peripheral iridotomy and medical therapy, lens extraction with trabeculectomy/goniosynechialysis may be beneficial. KEYWORDS

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“…Formulas were used to assess the risk of angle closure such as anterior segment length (ASL: summation of CCT, ACD, and LT) [ 19 ], the contribution of individual ocular components to the total axial (ACD/AL, LT/AL, VCD vitreous chamber depth/AL) [ 41 ], and the relative lens position (RLP: calculated as (ACD + 1/2LT)/AL) [ 42 ].…”

Section: Discussionmentioning

confidence: 99%

Ocular Biometric Characteristics of Chinese with History of Acute Angle Closure

Niu

Dong

Zhang

et al. 2018

Journal of Ophthalmology

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Purpose To investigate the biometric characteristics of Chinese patients with a history of acute angle closure (AAC). Methods In this clinic-based, retrospective, observational, cross-sectional study, biometric parameters of eyes were acquired from a general population of Chinese adults. The crowding value (defined as lens thickness (LT); central corneal thickness (CCT); anterior chamber depth (ACD)/axial length (AL)) was calculated for each patient. Logistic regression analysis was performed to identify risk factors for AAC. Receiver operating characteristic (ROC) curves were plotted, and biometric variables were compared to compile a risk assessment for AAC. Result This study included 1500 healthy subjects (2624 eyes, mean age of 66.54 ± 15.82 years) and 107 subjects with AAC (202 eyes, mean age of 70.01 ± 11.05 years). Eyes with AAC had thicker lens (P ≤ 0.001), shallower anterior chamber depth (P ≤ 0.001), and shorter axial length (P ≤ 0.001) than healthy eyes. Logistic regression analysis and ROC curve analysis indicated that a crowding value above 0.13 was a significant (P < 0.05) risk factor for the development of AAC. Conclusions Biometric parameters were significantly different between the eyes from the AAC group to the normal group. Ocular crowding value might be a new noncontact screening method to assess the risk of AAC in adults.

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New comparative clinical and biometric findings between acute primary angle-closure and glaucomatous eyes with narrow angle

Cited by 5 publications

References 21 publications

Malignant glaucoma

Malignant glaucoma

Assessment of Lens Thickness in Angle Closure Disease

Ocular Biometric Characteristics of Chinese with History of Acute Angle Closure

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