Descarte de córneas por sorologia positiva do doador no Banco de Olhos do Hospital São Paulo: dois anos de estudo

Viegas, Marco Túlio Chater; Pessanha, Lucas Calmon; Sato, Élcio Hideo; Hirai, Flávio E.; Adán, Consuelo Bueno Diniz

doi:10.1590/s0004-27492009000200009

Cited by 12 publications

(10 citation statements)

References 16 publications

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“…This is in agreement with other Brazilian studies 9,10 where seropositivity for hepatitis B was also a major cause of corneal discard.Of the three viral infections investigated in this study, the prevalence of HIV was the lowest, in agreement with other studies in literature 10,11 . The mean time between death and enucleation was 3.77 ± 2.18 hours, similar to other studies in the literature which found 3.8 ± 2.9 2 and 4.1 ± 2.8 12 hours.…”

Section: Cause Of Death Nsupporting

confidence: 93%

Characteristics of corneal donations in state of Piauí

Santos¹,

Bezerra²,

Melo³

2014

Revista Brasileira De Oftalmologia

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Os autores declaram não haver conflitos de interesse.Recebido para publicação em 31/12/2013 -Aceito para publicação em 28/8/2014 Most donors were male. The average age of the donors was 43.00 ± 16.01 years. The majority of transplanted corneas (78.6%) was optics. Were discarded 7.16% of corneal optics, mostly by new tectonic classification and detection of positive serology. The time of enucleation was 3.77 ± 2.18 hours and preservation was 6.86 ± 6.10 hours. The most frequent causes of death were external causes, followed by diseases of the circulatory, respiratory, digestive and genitourinary systems. The main indication for transplantation was bullous keratopathy, followed by keratoconus and corneal perforation. Conclusion: This study demonstrated the existence of factors associated with quality of corneas by BTOC as age, time between enucleation and preservation and cause of death. The main indication for transplantation was bullous keratopathy.Keywords

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Section: Cause Of Death Nsupporting

confidence: 93%

Characteristics of corneal donations in state of Piauí

Santos¹,

Bezerra²,

Melo³

2014

Revista Brasileira De Oftalmologia

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“…Nas doações de córneas, estudos internacionais relatam presença de sorologias positivas para hepatite B variando de 0,92 a 3,0% das doações (8,16) . Estudo recente, realizado no Banco de Olhos do Hospital São Paulo, mostrou uma positividade para hepatite B de 10,4% das doações no período de 2006 e 2007 (19) . Em nosso serviço, quando se leva em consideração a presença concomitante de sorologias positivas para anti-HBc e HBsAg, este índice de positividade cai de 47,4% para 1,5%, dentro da média de outros serviços internacionais (8,20) .…”

Section: Discussionunclassified

Características dos doadores de córneas do Banco de Olhos de Cascavel: impacto do exame anti-HBc para hepatite B

Shiratori¹,

Hirai²,

Sato³

2011

Arq. Bras. Oftalmol.

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Results: Mean age of donors was 54.2 ± 20.6 years and a greater proportion of men (64,7%) was observed. Mean time between death and enucleation was 3.8 ± 2.4 hours, cardiovascular diseases were the main cause of death (34.5%). Positivity of anti-HBc and HBsAg tests was 47.4% and 1.5%, respectively. Hepatitis B was the main reason for discarding corneas. Donors whose serologic tests were positive for anti-HBc had higher mean age compared to those with negative tests (p<0.001). Only 0.8% of all donations tested positive for hepatitis C and donors with positive HIV test were not seen in our study. Conclusions: Activities of the Cascavel Eye Bank significantly increased the availability of corneas for transplant in the State of Paraná. The main contraindication for availability of ocular tissues was positivity of serologic tests for anti-HBc. Biosafety studies should be performed in order to investigate the potential transmission of hepatitis B virus for donors with positive tests for anti-HBc. The inclusion of these donors would increase the number of corneas available for transplant.

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“…This fact is justifi ed by the prevalence of men in serious violent trauma, such as gunshot wounds or knife wounds, and that men are more commonly involved in car accidents (9)(10)(11) . In relation to age, data showed that age ranged from 3 to 73 years, with average age of 42.5 years.…”

Section: Discussionmentioning

confidence: 99%

Harnessing of corneas captured and processed for transplantation in an ocular tissue bank of North-eastern Brazil

Freire

Silva

Gomes

et al. 2014

Rev. Gaúcha Enferm.

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The aim of this study was to describe the harnessing of corneas captured and processed for transplantation in an ocular tissue bank in north-eastern Brazil. This was a transverse and retrospective study, with a sample group of 612 individuals whose corneas were donated and captured between January/2007 and July/2012. This study was approved by the Research Ethics Committee under number 007.0.294.000-10, and research was based on an instrument consisting of social, demographic and clinical data of the donors. Of the 1209 corneas captured, 868 were used and 341 were discarded. Of the 612 donors, the corneas of 597 (97.5%) were captured from both eyes, being that 423 (70.9%) of these corneas were used. Further studies are required on the reasons for discarding corneas and clarifications as to the conduct of professionals when processing corneas, considering the increase in the quantity of donors and the elevated number of discarded ocular tissue.

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Descarte de córneas por sorologia positiva do doador no Banco de Olhos do Hospital São Paulo: dois anos de estudo

Cited by 12 publications

References 16 publications

Characteristics of corneal donations in state of Piauí

Characteristics of corneal donations in state of Piauí

Características dos doadores de córneas do Banco de Olhos de Cascavel: impacto do exame anti-HBc para hepatite B

Harnessing of corneas captured and processed for transplantation in an ocular tissue bank of North-eastern Brazil

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