Fatores associados à qualidade da córnea doada pelo Banco de Olhos do Hospital São Paulo

Hirai, Flávio E.; Adán, Consuelo Bueno Diniz; Sato, Élcio Hideo

doi:10.1590/s0004-27492009000100011

Cited by 12 publications

(19 citation statements)

References 13 publications

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“…This study shows that the time between death and enucleation showed an increased period from 2011 to 2015 when compared to the period from 2006 to 2010. However, the time of both periods was higher than the one in other studies (9,17) . Although higher, this value is within the limit of six hours between death and enucleation (6,(18)(19)(20) , whereas another study shows that enucleation may be placed within 24 hours if the body is cooled (21) .…”

Section: Discussioncontrasting

confidence: 61%

Epidemiological profile of west center cornea donors

Silva¹,

Morato²,

Veneziano³

et al. 2016

Revista Brasileira De Oftalmologia

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Section: Discussioncontrasting

confidence: 61%

Epidemiological profile of west center cornea donors

Silva¹,

Morato²,

Veneziano³

et al. 2016

Revista Brasileira De Oftalmologia

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“…Este tempo considera-se adequado, pois a grande maioria dos óbitos são comunicados ao BOC quando o doador já se encontra na ACESC ou IML. O maior tempo decorrido entre o óbito e a captação do tecido ocular aumenta a chance de alteração do epitélio e do endotélio corneano, sendo este um fator que pode comprometer a avaliação do tecido doado, chegando até a contraindicar o tecido para uso em transplantes ópticos (10)(11) . Apesar deste fato, existem estudos que não mostram diferenças estatisticamente significantes entre a falência primária do botão corneano transplantado e o tempo de enucleação e preservação (8,11) .…”

Section: Discussionunclassified

Características dos doadores de córneas do Banco de Olhos de Cascavel: impacto do exame anti-HBc para hepatite B

Shiratori¹,

Hirai²,

Sato³

2011

Arq. Bras. Oftalmol.

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Results: Mean age of donors was 54.2 ± 20.6 years and a greater proportion of men (64,7%) was observed. Mean time between death and enucleation was 3.8 ± 2.4 hours, cardiovascular diseases were the main cause of death (34.5%). Positivity of anti-HBc and HBsAg tests was 47.4% and 1.5%, respectively. Hepatitis B was the main reason for discarding corneas. Donors whose serologic tests were positive for anti-HBc had higher mean age compared to those with negative tests (p<0.001). Only 0.8% of all donations tested positive for hepatitis C and donors with positive HIV test were not seen in our study. Conclusions: Activities of the Cascavel Eye Bank significantly increased the availability of corneas for transplant in the State of Paraná. The main contraindication for availability of ocular tissues was positivity of serologic tests for anti-HBc. Biosafety studies should be performed in order to investigate the potential transmission of hepatitis B virus for donors with positive tests for anti-HBc. The inclusion of these donors would increase the number of corneas available for transplant.

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“…This fact is justifi ed by the prevalence of men in serious violent trauma, such as gunshot wounds or knife wounds, and that men are more commonly involved in car accidents (9)(10)(11) . In relation to age, data showed that age ranged from 3 to 73 years, with average age of 42.5 years.…”

Section: Discussionmentioning

confidence: 99%

“…This type of infi ltration makes tissue transplantation impossible, as the aetiology of the lesion is unknown (14) . Incorrect use of the capturing and preservation technique is one of the causes of corneal tissue loss (6,9) . It is believed that corneal tissue may also be compromised during the hospital stay period, especially in the case of inadequate care in relation to preservation of corneas or during the stage between death of the individual and capturing of the tissue.…”

Section: Discussionmentioning

confidence: 99%

Harnessing of corneas captured and processed for transplantation in an ocular tissue bank of North-eastern Brazil

Freire

Silva

Gomes

et al. 2014

Rev. Gaúcha Enferm.

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The aim of this study was to describe the harnessing of corneas captured and processed for transplantation in an ocular tissue bank in north-eastern Brazil. This was a transverse and retrospective study, with a sample group of 612 individuals whose corneas were donated and captured between January/2007 and July/2012. This study was approved by the Research Ethics Committee under number 007.0.294.000-10, and research was based on an instrument consisting of social, demographic and clinical data of the donors. Of the 1209 corneas captured, 868 were used and 341 were discarded. Of the 612 donors, the corneas of 597 (97.5%) were captured from both eyes, being that 423 (70.9%) of these corneas were used. Further studies are required on the reasons for discarding corneas and clarifications as to the conduct of professionals when processing corneas, considering the increase in the quantity of donors and the elevated number of discarded ocular tissue.

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Fatores associados à qualidade da córnea doada pelo Banco de Olhos do Hospital São Paulo

Cited by 12 publications

References 13 publications

Epidemiological profile of west center cornea donors

Epidemiological profile of west center cornea donors

Características dos doadores de córneas do Banco de Olhos de Cascavel: impacto do exame anti-HBc para hepatite B

Harnessing of corneas captured and processed for transplantation in an ocular tissue bank of North-eastern Brazil

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