Características clínicas de 64 indivíduos portadores de uveítis posterior activa presumiblemente toxoplásmica en Pernambuco

Visual function and macular architecture in patients with inactive zone 2 and 3 toxoplasmic retinochoroiditis

“…In patients with inactive toxoplasmosis, no correlation was found between the VF defect and the lesion's size and location in 30% of the cases (10) . The involvement of the optic nerve in ocular toxoplasmosis has already been described by se veral authors (1,11,15) . In a retrospective study of 926 patients with active ocular toxoplasmosis, 49 (5.0%) patients presented optic disc swelling, and this was most frequently found in association with an active distant focus of retinochoroiditis (11) .…”

Anti-Toxoplasma gondii secretory IgA in tears of patients with ocular toxoplasmosis: immunodiagnostic validation by ELISA

“…Except for one patient, all individuals of the APUPT group presented with the reactivated illness, showing retinochoroidal scars (Lynch et al 2008) and IgM-negative sera. Only one patient had acquired ocular toxoplasmosis without scars; this patient tested positive for IgM, had an IgG dilution of 1:320 and was positive for sIgA in the tears.…”

“…Consistent with previous reports (Schellini et al 1993, Sebben et al 1995, Lynch et al 2004, APUPT tends to occur more frequently in younger individuals; in this study, 45.5% of cases were between 10-30 years. This is an important aspect, since the disease leads to longterm morbidity when scars appear in the macula (Lynch et al 2008). This fact affects the quality of life of the individual and can deprive patients of their ability to work.…”

Ocular toxoplasmosis: evaluation of lacrimal - specific secretory IgA levels in both patients with active and inactive phases of the disease

“…This shows that the patients studied tend to have recurrence of ocular toxoplasmosis between the second and fourth decades, as discussed by Holland (2004) and Lynch et al (2008). A minimum follow-up time of two years was used to reduce the probability of detecting antibodies related to the acute event because serum IgM and IgA can be detected up to 18 months and nine months, respectively, following systemic toxoplasmosis (Kodym et al 2007).…”