Pseudohypopyon immediately after intravitreal injection of triamcinolone acetonide: case reports

Abstract

Report on the development of pseudohypopyon immediately after intravitreal injection of triamcinolone acetonide (TAAC). Two phakic patients presenting with a transient pseudohypopyon after having been treated with intravitreal triamcinolone. One had a clinically significant macular edema with cystoid component (CSME with CMS) and the other, active Vogt-Koyanagi-Harada (VKH) with serous retinal detachment of the macula. One eye from each patient developed a pseudohypopyon with crystal deposits adherent to the corneal endothelium. In one case it appeared right after the injection and disappeared spontaneously in 24 hours. In the other patient it appeared on day 3 and disappeared also spontaneously within 2 days. The pseudohypopyon is an important sign that can be observed after intravitreal injection of TAAC, in phakic patients, with spontaneous resolution and without complication. The pseudohypopyon caused by the deposition of TAAC in the anterior chamber immediately after its injection into the vitreous should be differentiated from other forms of hypopyon associated with this type of treatment.

Toxoplasmosis retinochoroiditis after photodynamic therapy and intravitreal triamcinolone for a supposed choroidal neovascularization: a case report

“…Lately, the association of PDT and intravitreal injection of triamcinolone acetonide has shown potential short-term benefit in the management of CNV secondary to AMD (3)(4)(5) . Although effective in the treatment of some diseases of the posterior segment, intraocular triamcinolone can cause side effects, especially ocular hypertension, cataract and pseudohypopyon (6)(7)(8)(9) .…”

Pseudohypopyon following intravitreal triamcinolone acetonide injection in a phakic eye

“…Pseudohypopyon following IVTA injection occurs because of the sedimentation of triamcinolone acetonide crystals in the anterior chamber (AC) and can closely mimic infectious and sterile endophthalmitis 1 . It is uncommon in phakic eyes 2–4 …”

“…The symptoms can range from mild discomfort to sudden decrease in vision. The onset of hypopyon can vary from a few hours to 3 days 2 . Sometimes it can be difficult to determine the particulate nature of the hypopyon.…”

Tratamento do edema macular difuso do diabético com triancinolona intravítrea e fotocoagulação com laser de argônio

“…O paciente apresenta um olho calmo e sem dor e, raramente, queixa-se de baixa visual 67,69,82,83 . Os cristais de triancinolona podem sofrer turbilhonamento durante a aplicação, causando uma turvação vítrea e, além disto, podem migrar para a câmara anterior e se depositarem inferiormente, aparentando um hipópio (pseudo-hipópio) 69,81,83,84 .…”