Corneal thickness and daily curve of intraocular pressure in suspected and glaucomatous patients

Effect of central corneal thickness on Goldmann applanation tonometry measures—a different result with different pachymeters

“…a correlation coefficient, Pearsons r value, of 0.6) for the present group of subjects is much higher than those reported in many studies. While there have been other correlations of this strength (r= 0.631) for Perkins tonometry versus ultrasound pachymetry in glaucoma suspects, it has still been argued that it is "of doubtful clinical significance" [17]. Such a conclusion is probably based on a perspective that even such a strong association could still be dogmatically viewed as only accounting for one third (i.e.…”

Age-Related Differences in Central Corneal Thickness Alterations Caused by Short-Term Hypobaric Hypoxia

“…Another point to consider is that the ability to control corneal hydration decreases with age, 19 and it has been shown that young adults have a noticeably higher night edema reabsorption rate than do older people. 18 The decrease in the control of corneal hydration might be due to the reduction in corneal endothelial cells with age. [23][24][25][26][27] In summary, it may be said that as humans get older, the corneal endothelium becomes more susceptible to hypoxia.…”

“…[14][15][16][17] It has also been reported that young adults had a higher rate of night edema reabsorption than did older individuals. 18 Corneal hydration control seems to decrease 19 and corneal rigidity seems to change [20][21][22] with age. Corneal endothelial cells are present in a certain number at birth, and they decrease in number across the life span.…”

Correlação entre a espessura corneana central e o comprimento axial ocular nos portadores de glaucoma e em olhos normais

“…Não vimos referência ao horário em que foi realizada a paquimetria na maioria dos trabalhos pesquisados. De acordo com estudos de alguns autores, não houve significância estatística na variação da espessura central da córnea durante o dia, portanto, somente uma medida da espessura corneana é suficiente (8) . No entanto, outro estudo relatou que a espessura corneana é variável durante o período de 24 horas (27) .…”

“…Numerosos estudos têm demonstrado correlação entre a espessura corneana central e a pressão intraocular (4)(5)(8)(9)(10) e outros relacionados com dimensões oculares (comprimento axial, profundidade da câmara anterior) e progressão do glaucoma (2,(11)(12)(13)(14)(15)(16) . Porém, existem poucos relatos na literatura (7,(17)(18)(19) associando a espessura corneana e o comprimento axial do globo ocular nos portadores de glaucoma, o que nos motivou a realizar este trabalho.…”