Correlação entre a espessura corneana central e o comprimento axial ocular nos portadores de glaucoma e em olhos normais

Mello, Paula Resende Aquino de Assis Pereira; Meirelles, Sergio Henrique Sampaio; Júnior, Haroldo Vieira de Moraes

doi:10.1590/s0004-27492009000400012

Cited by 6 publications

(3 citation statements)

References 24 publications

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“…There are reasonable data showing differences in CCT between various ethnic groups 14,15. The mean CCT in our study (544.6 μm) was similar to that of 545.2 μm reported for the Caucasian population by Nemesure et al and within the limits for mean CCT reported by other studies, ie, 520–579 μm 6,16–18. The corneas of African Americans have been reported to be thinner and those of Caucasians and Mongoloids as thicker 6,9,14,15,19–23.…”

Section: Discussionsupporting

confidence: 90%

Age-related changes in central corneal thickness in normal eyes among the adult Lithuanian population

Galgauskas¹,

Juodkaite²,

Tutkuviene³

2014

CIA

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BackgroundThe purpose of this study was to estimate mean central corneal thickness (CCT) and determine whether there are any correlations between CCT, age, and sex in the adult Lithuanian population.MethodsA total of 1,650 Caucasians of Lithuanian origin (aged 18–89 years) comprising 688 (41.7%) men and 962 (58.3%) women were examined. Subjects were stratified by age into seven groups. CCT was measured using ultrasonic pachymetry. Correlations between CCT, age, and sex were sought.ResultsMean (± standard deviation) CCT for both eyes was 544.6±30.5 μm. Mean CCT was 545.2±30.5 μm in the left eye and 544.6±30.5 μm in the right eye, and was 545.0±25.6 μm in men and 544.4±33.5 μm in women. Mean CCT was 550.8±35.7 μm in subjects aged 18–29 years, 557.5±27.6 μm in those aged 30–39 years, 551.3±31.4 μm in those aged 50–59 years, 544.0±31.4 μm in those aged 50–59 years, 544.2±31.6 μm in those aged 60–79 years, 535.1±27.8 μm in those aged 70–79 years, and 530.1±16.8 μm in those aged 80–89 years. No statistically significant difference in CCT was found between the sexes (P>0.05). However, there was a significant difference in subjects aged 18–29 years; men had higher CCT than women (P<0.05). A statistically significant negative correlation was found between CCT and age (r=-0.263, P<0.05) that was stronger in men (r=-0.406, P<0.05) than in women (r=-0.118, P<0.05).ConclusionThe mean CCT in adult Lithuanians was 544.6±30.5 μm, of the left eye 545.2±30.5 μm and of the right – 544.6±30.5 μm. CCT of the right eye was equal to the CCT of both eyes. Mean CCT was 545.0±25.6 μm in men and 544.4±33.5 μm in women. Young men tended to have higher CCT than women. CCT decreases over the lifetime, meaning that older people have thinner corneas. CCT’s dependence on age is stronger in men.

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Section: Discussionsupporting

confidence: 90%

Age-related changes in central corneal thickness in normal eyes among the adult Lithuanian population

Galgauskas¹,

Juodkaite²,

Tutkuviene³

2014

CIA

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“…There are some studies on CCT in PACG reporting no difference in CCT between PACG and controls. [ 12 13 ] However, these studies suffer from small sample size. Two studies investigated CCT in Asian populations and reported no difference in CCT between various glaucoma subtypes.…”

Section: Discussionmentioning

confidence: 99%

Central corneal thickness in primary angle closure and open angle glaucoma

Moghimi¹,

Torabi²,

Hashemian³

et al. 2014

J Ophthalmic Vis Res

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Purpose:To quantitatively analyze central corneal thickness (CCT) in patients with primary angle closure glaucoma (PACG) and primary open-angle glaucoma (POAG), and to evaluate its correlation with severity of glaucoma.Methods:In this retrospective study, records of patients with previously diagnosed POAG or PACG at a tertiary glaucoma service were reviewed. CCT was measured by ultrasound pachymetry. Mean deviation (MD) on visual field (VF) testing was recorded for glaucoma severity determination. CCT and age- and sex-adjusted CCT were compared among the study groups using Student's t-test and analysis of covariance (ANCOVA), respectively. Univariate and multivariate regression models were used for correlation of age, MD and CCT.Results:A total of 115 patients with PACG, 215 with POAG, and 100 normal controls were included with mean age of 64.1 ± 10.4, 59.9 ± 10.5, and 62.04 ± 10.80 years, respectively. CCT was thicker in PACG eyes (545.5 ± 46.1 μm) as compared to POAG eyes (531.7 ± 37.3 μm) and controls (531.0 ± 38.3 μm) even after age and gender adjustment (ANCOVA, P = 0.05). CCT was found to decrease with increasing age only in the POAG group (β = -0.57, P = 0.01). Disease severity (MD of VF) was significantly and inversely correlated with CCT in both POAG and PACG eyes (β = 1.89, P = 0.02; and β = 1.38, P = 0.04, respectively) after age and sex correction.Conclusion:PACG eyes had thicker CCT as compared to POAG and normal healthy eyes in Iranian subjects. Severity of the disease was inversely correlated with CCT in eyes with both POAG and PACG.

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“…In studies evaluating CCT, the mean CCT was found to be between 520 and 579 µm. 10,11 In our study, it was 542.5 µm. Kazancı et al showed that the CCT was 541.5 µm (214 eyes, range 18-56 years) in their study with the Sirius topography device in a Turkish population.…”

Section: Discussionmentioning

confidence: 52%

Evaluation of Age-Related Changes in Corneal Parameters Using Scheimpflug Imaging: A Prospective Clinical Study Scheimpflug Görüntüleme Tekniği Kullanılarak Yaşa Bağlı

Duran¹

2023

Turkiye Klinikleri J Ophthalmol

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Correlação entre a espessura corneana central e o comprimento axial ocular nos portadores de glaucoma e em olhos normais

Cited by 6 publications

References 24 publications

Age-related changes in central corneal thickness in normal eyes among the adult Lithuanian population

Age-related changes in central corneal thickness in normal eyes among the adult Lithuanian population

Central corneal thickness in primary angle closure and open angle glaucoma

Evaluation of Age-Related Changes in Corneal Parameters Using Scheimpflug Imaging: A Prospective Clinical Study Scheimpflug Görüntüleme Tekniği Kullanılarak Yaşa Bağlı

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