Injeção intravítrea de acetato de triancinolona no tratamento da síndrome de Vogt-Koyanagi-Harada

Andrade, Rafael; Muccioli, Cristina; Farah, Michel Eid

doi:10.1590/s0004-27492004000300005

Cited by 8 publications

(5 citation statements)

References 14 publications

(17 reference statements)

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“…In cases where patients are resistant to corticosteroids and also fail to respond to be immunomodulatory therapy, intravenous immunoglobulin may be a viable treatment option 60 . An intravitreous injection of triamcinolone can clear up the inflammatory process and the intraretinal and subretinal exsudate leading to significant improvements to visual acuity 61 .…”

Section: Treatmentmentioning

confidence: 99%

Síndrome de Vogt-Koyanagi-Harada e o seu acometimento multissistêmico

Mota¹,

Santos²

2010

Rev. Assoc. Med. Bras.

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Vogt-Koyanagi-Harada's syndrome is a rare disease that affects tissues containing melanocytes, such as the eyes, central nervous system, inner ear and skin. Some ethnic groups have a higher probability of developing the disease, including Asians, Indians and Latin Americans and females are affected more often. Methods: Literature was reviewed in books, articles published on the internet and papers available in the online databases MEDLINE, LILACS and SciELO. Texts were selected that focused on otorhinolaryngological symptoms. Literature review: The disease probably has autoimmune etiology, with aggression occurring on the surface of melanocytes by promoting inflammatory reaction in which T lymphocytes predominate. The allele most often found in association with this disease is HLA DRB1*0405. Clinical manifestations are divided into four stages: prodromal, uveitic, chronic and recurrent. Otorhinolaryngological symptoms occur during the uveitic stage and are characterized by bilateral sensorineural hearing loss, tinnitus and vestibular symptoms. Diagnosis is made according to the diagnostic criteria for the disease. Treatment is primarily with corticosteroids. Conclusions: It is important that professionals in other specialties are able to recognize Vogt-Koyanagi-Harada's syndrome, because late diagnosis can lead to ocular and cutaneous sequelae.

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Section: Treatmentmentioning

confidence: 99%

Síndrome de Vogt-Koyanagi-Harada e o seu acometimento multissistêmico

Mota¹,

Santos²

2010

Rev. Assoc. Med. Bras.

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“…1 The inflammatory and exudative retinal process can improve with the application of intravitreal triamcinolone injection. 17 Some studies suggest that sub-tenonian injection of triamcinolone should be an initial treatment for relapse of VKH in pregnant women. 18 The study patient improved only with prolonged use of oral and topical corticosteroids, not requiring immunomodulatory therapy.…”

Section: Discussionmentioning

confidence: 99%

Vogt-koyanagi-harada syndrome in a young patient

Matos¹,

Ciarlini²,

Bastos³

2020

IJFCM

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Vogt-Koyanagi-Harada syndrome is a chronic bilateral autoimmune intraocular inflammation in which antibodies are produced against melanocyte tissues associated with neurological and skin changes, including headache, tinnitus, vitiligo, polyiosis, and alopecia. The disease occurs in distinct phases: the prodromal phase, the acute uveitic phase, the chronic or convalescent phase, and the chronic recurrent phase. The treatment should be early and is made using corticosteroids and immunomodulatory drugs. We report a case of a young patient with the syndrome who developed recurrence of the disease during oral corticosteroid weaning, and was treated with adalimumab.

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“…Porém o seu uso não é Pio= pressão intra-ocular; AV= acuidade visual; Fem.= feminino; Masc.= masculino; OD= olho direito; OE= olho esquerdo; Mov. de mão= movimentos de mão isento de riscos, várias complicações podem ocorrer, como perfuração de globo ocular, oclusões vasculares, catarata, blefaroptose, proptose, estrabismo, infecções e quemose (7)(8)(9)(10) . Dentre todas as possíveis complicações, aquela que deve-se ter um cuidado especial, seja devido a sua freqüência, seja devido a sua gravidade é o aumento da pressão intra-ocular (2) .…”

Section: Discussionunclassified