Alterações fundoscópicas e sua associação clínica empacientes com tuberculose, no Distrito Federal

Mendes, Gustavo Federici; Toríbio, Rachel Cortinhas; Alvares, Tomaz Aiza; Alvares, Rosicler Rocha Aiza

doi:10.1590/s0004-27492003000300019

Cited by 2 publications

(2 citation statements)

References 11 publications

(26 reference statements)

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“…The primary ophthalmologic outcome was evaluated after two-months of anti-TB treatment based on previous studies that suggested a favorable therapeutic response by the end of intensive treatment phase. 5 , 7 …”

Section: Methodsmentioning

confidence: 99%

“…Studies to date have only reported the frequency of ocular TB and its clinical manifestations without assessing visual acuity or have examined a single assessment of visual acuity without monitoring the effects of treatment. 7 , 8 , 9 , 10 This study aimed to assess visual acuity of TB patients before and after two months of treatment with anti-tuberculous therapy.…”

Section: Introductionmentioning

confidence: 99%

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The impact of ocular tuberculosis on vision after two months of intensive therapy

Oliveira

Passos

Hadad

et al. 2018

The Brazilian Journal of Infectious Diseases

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Tuberculosis is an infectious disease of global importance with major economic and social burden accounting for 25% of all avoidable deaths in developing countries. Extrapulmonary involvement may occur either in association with clinically apparent pulmonary tuberculosis or in isolation. This cross-sectional descriptive study aimed to evaluate the impact of ocular tuberculosis in visual acuity at baseline and after two months of intensive anti-tuberculous therapy. A sample of 133 pulmonary tuberculosis patients, seven disseminated tuberculosis, and three pleural tuberculosis patients was evaluated. All patients underwent routine ophthalmic evaluation, including assessment of visual acuity, biomicroscopy, applanation tonometry, indirect ophthalmoscopy, and fluorescent angiography as appropriate. None of the patients had impaired visual acuity due to tuberculosis. A rate of 4.2% (6/143) of ocular involvement was found. None of the patients with ocular involvement were HIV-infected. Of the six patients with ocular involvement, five met the diagnostic criteria for probable and one for possible ocular lesions. As for the type of ocular lesions, two patients had bilateral findings: one had sclerouveitis and the second had choroidal nodules. The other four patients presented with unilateral lesions: peripheral retinal artery occlusion in the right eye (one case), choroidal nodules in the left eye (one case), and choroidal nodules in the right eye (two cases). Patients progressed favorably after two month of intensive therapy, with no significant reduction in vision.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The impact of ocular tuberculosis on vision after two months of intensive therapy

Oliveira

Passos

Hadad

et al. 2018

The Brazilian Journal of Infectious Diseases

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Fundus Changes in Milliary Tuberculosis: A Retrospective Cohort Study

Jain¹

2019

DJO

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Introduction: Milliary tuberculosis occurs due to haematogenous spread of infection. It is assumed that intraocular tuberculosis is spread hematogenously from primary infection to elsewhere. The choroidal tubercles may be one of the earliest signs of milliary disease and is probably the most common form of ocular tuberculosis.Methods: This is a retrospective observational single site study of 113 patients with milliary tuberculosis from 2001 to 2015. Fundus examination was done after full dilatation of the pupil with direct and indirect ophthalmoscope. The diagnosis of intraocular tuberculosis was presumed to be based on suggestive ocular lesion in context of evidence of systemic infection and response to antitubercular treatment.Results: There were 77 females (68%) and 36 (32%) males. The commonest age group was 21 to 40 years as 67 (59.3%) patients belonged to this productive age group. Eighty eight (77.9%) patients were from rural areas. Fundus changes were present in 14 patients (12.39%) and these were choroidal tubercles (8.8%), papillitis (4.4%), macular edema (0.9%) and vitritis (0.9%). Choroidal tubercles were present in 10 patients. Among these, two had associated papillitis and one also had vitritis. Three patients had only papillitis and in another one, only macular edema was present. Papillitis was present in five patients in our study. HIV did not increase the incidence of ocular lesions. Conclusion:The most common fundus changes were choroidal tubercles and optic neuropathy in our series. Early detection of these choroidal tubercles may be helpful in diagnosis as well as in treatment. The optic nerve may be involved not only by the toxic effect of anti-tubercular drug but also in the disease process itself.

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Alterações fundoscópicas e sua associação clínica empacientes com tuberculose, no Distrito Federal

Cited by 2 publications

References 11 publications

The impact of ocular tuberculosis on vision after two months of intensive therapy

The impact of ocular tuberculosis on vision after two months of intensive therapy

Fundus Changes in Milliary Tuberculosis: A Retrospective Cohort Study

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