Endocrine diseases, perspectives and care in Turner syndrome

Collett‐Solberg, Paulo Ferrez; Gallicchio, Carla Tavares; Coelho, Simone Cristina da Silva; Siqueira, Rodrigo de Azeredo; Alves, Solange Travassos de Figueiredo; Guimarães, Marília M.

doi:10.1590/s0004-27302011000800008

Cited by 14 publications

(11 citation statements)

References 62 publications

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“…Secondary autoimmune disease is one of the most prominent features of TS due to aneuploidy of the X chromosome (19). TS causes a variety of autoimmune diseases such as thyroiditis, colitis, celiac disease, type 1 diabetes, and psoriasis, though the most common is autoimmune thyroiditis (20). Follow-up studies have indicated that the incidence of autoimmune thyroiditis in patients with TS is 3.2% (21).…”

Section: Autoimmune Diseasessmentioning

confidence: 99%

A basic understanding of Turner syndrome: Incidence, complications, diagnosis, and treatment

Cui

Shi

et al. 2018

IRDR

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Turner syndrome (TS), also known as Congenital ovarian hypoplasia syndrome, occurs when the X chromosome is partially or completely missing in females. Its main clinical manifestations include growth disorders, reproductive system abnormalities, cardiovascular abnormalities, and autoimmune diseases. TS is highly prevalent in China. Timely diagnosis is crucial, and non-invasive prenatal DNA testing can identify TS and other diseases. Treatment of TS mainly involves administration of growth hormone combined with very low doses of estrogen to increase the patient's height. This article describes the incidence, complications, diagnosis, and treatment of TS.

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Section: Autoimmune Diseasessmentioning

confidence: 99%

A basic understanding of Turner syndrome: Incidence, complications, diagnosis, and treatment

Cui

Shi

et al. 2018

IRDR

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“…This predisposition to obesity may be exaggerated in appearance by the characteristics of TS patients such as shield-like chest, stocky build and short stature with relatively short legs. The patients should be evaluated regularly with appropriate counseling to avoid obesity ( 32 ).…”

Section: Discussionmentioning

confidence: 99%

Growth curves for Turkish Girls with Turner Syndrome: Results of the Turkish Turner Syndrome Study Group

Darendelıler¹,

Yeşilkaya²,

Bereket³

et al. 2015

Jcrpe

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Objective:Children with Turner syndrome (TS) have a specific growth pattern that is quite different from that of healthy children. Many countries have population-specific growth charts for TS. Considering national and ethnic differences, we undertook this multicenter collaborative study to construct growth charts and reference values for height, weight and body mass index (BMI) from 3 years of age to adulthood for spontaneous growth of Turkish girls with TS.Methods:Cross-sectional height and weight data of 842 patients with TS, younger than 18 years of age and before starting any therapy, were evaluated.Results:The data were processed to calculate the 3rd, 10th, 25th, 50th, 75th, 90th and 97th percentile values for defined ages and to construct growth curves for height-for-age, weight-for-age and BMI-for-age of girls with TS. The growth pattern of TS girls in this series resembled the growth pattern of TS girls in other reports, but there were differences in height between our series and the others.Conclusion:This study provides disease-specific growth charts for Turkish girls with TS. These disease-specific national growth charts will serve to improve the evaluation of growth and its management with growth-promoting therapeutic agents in TS patients.

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“…In the first instance, bone mineral status should been assessed in childhood to detect TS subjects at increased risk of bone impairment and in order to carry out preventive measures ( 25 ). In particular, it is preferable to use diagnostic methods that take into account for reduced bone size of these patients, such as pQCT or volumetric transformation of DXA data ( 88 ).…”

Section: Management Of Bone Fragility In Tsmentioning

confidence: 99%

Bone Fragility in Turner Syndrome: Mechanisms and Prevention Strategies

et al. 2016

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Bone fragility is recognized as one of the major comorbidities in Turner syndrome (TS). The mechanisms underlying bone impairment in affected patients are not clearly elucidated, but estrogen deficiency and X-chromosomal abnormalities represent important factors. Moreover, although many girls with TS undergo recombinant growth hormone therapy to treat short stature, the efficacy of this treatment on bone mineral density is controversial. The present review will focus on bone fragility in subjects with TS, providing an overview on the pathogenic mechanisms and some prevention strategies.

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Endocrine diseases, perspectives and care in Turner syndrome

Cited by 14 publications

References 62 publications

A basic understanding of Turner syndrome: Incidence, complications, diagnosis, and treatment

A basic understanding of Turner syndrome: Incidence, complications, diagnosis, and treatment

Growth curves for Turkish Girls with Turner Syndrome: Results of the Turkish Turner Syndrome Study Group

Bone Fragility in Turner Syndrome: Mechanisms and Prevention Strategies

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