2011
DOI: 10.1590/s0004-27302011000100004
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Avaliação de fatores clínicos, laboratoriais e ultrassonográficos preditores de malignidade em nódulos tiroidianos

Abstract: RESUMOObjetivo: Avaliar risco de malignidade de nódulos tiroidianos por meio de aspectos clínicos, laboratoriais, ultrassonográficos e citológicos. Pacientes e métodos: 741 nódulos de 407 pacientes. Resultados: A citologia foi benigna (60,5%), indeterminada (23,3%), maligna (8,6%) ou não diagnóstica (7,6%). A prevalência de câncer nas citologias indeterminadas foi 18,5% (16% nas lesões foliculares, 44% nas suspeitas). O diagnóstico de malignidade foi 17,2% (n = 70). A frequência de câncer em mulheres (15,2%) f… Show more

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Cited by 6 publications
(6 citation statements)
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“…In our cohort, we identified a higher incidence of cancer in males and in patients with a single nodule, but there were no significant differences in the diameter of the benign and malignant lesions. We observed that the patients with carcinoma were younger than those in the control group (mean age 45.8 years and 50 years, respectively), but this association is controversial in the literature, with contradictory findings in several studies [30][31][32].…”
Section: Discussionmentioning
confidence: 66%
“…In our cohort, we identified a higher incidence of cancer in males and in patients with a single nodule, but there were no significant differences in the diameter of the benign and malignant lesions. We observed that the patients with carcinoma were younger than those in the control group (mean age 45.8 years and 50 years, respectively), but this association is controversial in the literature, with contradictory findings in several studies [30][31][32].…”
Section: Discussionmentioning
confidence: 66%
“…In Brazil, the current estimated incidence of thyroid cancer is 24 cases per 100,000 inhabitants, and it is the fourth-most common neoplasm found in women [1, 2, 7]. As thyroid US has become widely used, a higher number of thyroid nodules have been detected, resulting in an increased diagnosis of thyroid cancer, particularly microcarcinomas (< 10 mm in diameter) [8-10].…”
Section: Introductionmentioning
confidence: 99%
“…Al igual que lo encontrado por otros grupos 6,26,27,28 , el aumento del flujo Doppler intranodular fue mucho mayor en los nódulos malignos y muy ocasional en los benignos; en el presente trabajo, casi en la mitad de los nódulos por cáncer, esta característica aislada tiene una fuerza de concordancia débil.…”
Section: Discussionunclassified
“…Todos estos hallazgos muestran coincidencias con lo propuesto recientemente por algunos autores 27,28 . Lo primero es que el tamaño del nódulo para efectos de diagnóstico de cáncer de tiroides no es un factor decisivo en la toma o no de una muestra mediante biopsia por aspiración con aguja fina y, por lo tanto, a los nódulos menores de 1 cm con criterios ecográficos sospechosos, aun en pacientes sin factores de riesgo, se les debe practicar biopsia por aspiración con aguja fina.…”
Section: Discussionunclassified