Relação da ginecomastia puberal com o índice de massa corporal em amostra de adolescentes atendidos em Unidade de Pacientes Externos de Hospital Universitário

Rivera, Nádia F.; Eisenstein, Evelyn; Cardoso, Catarina

doi:10.1590/s0004-27302009000400008

Cited by 9 publications

(3 citation statements)

References 11 publications

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“…It demonstrated that pubertal gynecomastia is associated with a higher BMI. 16 A similar finding was reported by Ersöz et al, who found a significant increase in body weight and BMI in the gynecomastia group compared with healthy controls. 14 …”

Section: Discussionsupporting

confidence: 87%

Hormonal, anthropometric and lipid factors associated with idiopathic pubertal gynecomastia

Alwan

Azkawi

Badri

et al. 2013

Annals of Saudi Medicine

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BACKGROUND AND OBJECTIVESTo determine factors associated with pubertal gynecomastia.DESIGN AND SETTINGSA cross-sectional study among healthy male school children and adolescents in Riyadh, Saudi Arabia.METHODSSubjects were selected from diverse socioeconomic backgrounds. Tanner stage, height, weight, blood hormonal levels (leutilizing hormone [LH], follicle-stimulating hormone [FSH], total testosterone, and estradiol), and anthropometric and lipid parameters (body mass index [BMI], triglycerides, high-density lipoprotein [HDL], and low-density lipoprotein [LDL]), were collected and compared in children with and without gynecomastia.RESULTSThe study included 542 children and adolescents. Median (interquartile range) age in the whole group was 11(8–13) years. The prevalence of gynecomastia was 185/542 (34%), with a peak at age 14. The 2 groups compared had nonsignificant difference in cholesterol (P=.331), LH (P=.215) and FSH (P=.571) levels. Those with gynecomastia were significantly older, had lower gonad stage, had higher anthropometric (height, weight, and BMI), and lipid (triglycerides, HDL, and LDL) values. In multivariate regression analysis, factors significantly associated with gynecomastia were BMI (odds ratio [OR]=1.05; 95%CI 1.00–1.10; P=.013), HDL (OR=0.42; 95%CI 0.19–0.92; P=.03), and gonad (Stage II OR=2.23; 95%CI 1.27–3.92; P=.005, Stage III OR=6.40; 95%CI 2.70–15.0; P<.0001, Stage IV OR=3.24; 95%CI 1.32–7.95; P=.01, Stage V OR=1.37; 95%CI 0.52–3.56; P=.53, compared with stage I).CONCLUSIONPubertal gynecomastia tends to increase in mid-puberty. In our setting, BMI, HDL, and gonad stage were the major factors associated with the development of pubertal gynecomastia.

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Section: Discussionsupporting

confidence: 87%

Hormonal, anthropometric and lipid factors associated with idiopathic pubertal gynecomastia

Alwan

Azkawi

Badri

et al. 2013

Annals of Saudi Medicine

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“…also observed correlation of mammary diameters to higher BMI percentiles. [19] Aromatase activity increases with elevation of BMI, thereby causing increased peripheral conversion of androgens to estradiol. [220] Obese patients had a younger age at onset of gynecomastia as compared to lean patients.…”

Section: Discussionmentioning

confidence: 99%

Adolescent gynecomastia is associated with a high incidence of obesity, dysglycemia, and family background of diabetes mellitus

Kulshreshtha

Arpita

Rajesh

et al. 2017

Indian J Endocr Metab

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Background:Gynecomastia during adolescence is common though etiology is not clear. We studied the clinical and hormonal profile of adolescent patients with gynecomastia.Methodology:Patients who had onset of breast development between age 10 and 20 years were included in this study. Their clinical profile, biochemical, and hormonal parameters were studied.Results:Of 94 patients with gynecomastia, 4 had hypogonadotropic hypogonadism, 4 had hypergonadotropic hypogonadism, and 1 had fibroadenosis, but in majority (90.4%), no apparent cause for breast enlargement was evident. In the idiopathic group, majority were obese (63%). Fourteen (16%) patients had impaired fasting glucose or impaired glucose tolerance. Another twenty patients had subtle abnormalities (high 1 h glucose or glucose peak at 2 h). Twenty-nine percent of lean and 38% of obese patients had mild abnormalities in glucose profile. Sixty percent of patients had family background of diabetes. Obese patients had lower testosterone as compared to lean patients; however, estradiol, luteinizing hormone, and follicle-stimulating hormone levels were similar in the two groups.Conclusion:Gynecomastia during adolescence is associated with obesity, dysglycemia, and family background of diabetes mellitus.

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“…Rivera et al 20 evaluated the association between pubertal gynecomastia and body mass index and concluded that a significant correlation occurs between pubertal gynecomastia and a higher body mass index in adult life. Bonganha et al 21 evaluated the relationship between resting metabolic rate and the body composition of postmenopausal women and concluded that body composition correlates with lean mass and waist circumference.…”

Section: Methodsmentioning

confidence: 99%

Metabolic and infectious pathologies in Brazilian medical literature: a review

Rocha-e-Silva¹

2010

Clinics

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OBJECTIVE: This review of original reports on metabolic and infectious diseases that were recently published in Brazilian journals is designed to inform the readership of CLINICS about their content.METHODS: I conducted a search in PubMed for original research articles (clinical or basic research) recently published (2008)(2009) by Brazilian medical and biological periodicals. Papers on metabolic pathologies were retrieved by searching for appropriate keywords such as metabolic syndrome and obesity. Papers on infectious disease were obtained by entering 15 different keywords for the most commonly occurring pathologies. Review articles, editorials, letters to the editor, and case reports were manually excluded. Selected titles were then categorized into appropriate sub-categories. RESULTS:This search produced a total of 123 articles, which filtered down to 72 articles after eliminating editorials, review articles, letters to the Editor and case reports.

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Relação da ginecomastia puberal com o índice de massa corporal em amostra de adolescentes atendidos em Unidade de Pacientes Externos de Hospital Universitário

Cited by 9 publications

References 11 publications

Hormonal, anthropometric and lipid factors associated with idiopathic pubertal gynecomastia

Hormonal, anthropometric and lipid factors associated with idiopathic pubertal gynecomastia

Adolescent gynecomastia is associated with a high incidence of obesity, dysglycemia, and family background of diabetes mellitus

Metabolic and infectious pathologies in Brazilian medical literature: a review

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