Importância da avaliação da função tireoidiana em pacientes com diabetes mellitus

Silva, Regina do Carmo

doi:10.1590/s0004-27302005000200003

Cited by 10 publications

(8 citation statements)

References 6 publications

(15 reference statements)

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“…The effects of iodothyronine on the various metabolic pathways are assessed by specific tests, such as free T4, free T3 and TSH. 8,9,10,13 Studies comparing the incidence of specific thyroid dysfunction (TD) between type 1 and type 2 diabetic patients show different inferences i.e. general consensus is TD is more prevalent among patients with type 2 diabetes mellitus, although some studies show a greater prevalence in type 1 DM; with female prevalence higher than males, proportionate increment of TD with age of onset, longer duration of diabetes, poorer glycaemic control and with patients having relatively higher abnormal body mass index and other co-morbid states like cardiovascular diseases namely hypertension, atherosclerosis and obesity.…”

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confidence: 99%

Study of thyroid dysfunction in type 2 diabetes mellitus

2020

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Background: Aim was to study prevalence of thyroid dysfunction in type II diabetes mellitus (T2DM) patients.Methods: The present study was a cross sectional observational study, which focused on cases of diabetes mellitus. Study was conducted in Departments of Medicine, SBKS MI & RC, a tertiary care centre for a period of 6 months. All the patients of T2DM were included. Total of 263 patients were enrolled which involved indoor, outpatient and diabetic clinic attending patients. A detailed history taking, clinical examination and relevant investigations (Hb%, Total count, platelet count, serum creatinine, FBS, PP2BS, HbA1C, S.TSH, F.T3 and F.T4). Appropriate statistical analytics were used and important correlations and conclusions were drawn.Results: A study of thyroid dysfunction (TD) in T2DM patients which included 263 diabetic patients, out of them 67 had thyroid dysfunction. Out of these 67 patients 43 were female and 24 were male. This suggests that female was more prone to thyroid dysfunction than males. Out of 67 TD patients, 42 were above the age of 50 year. So, as the age increases the prevalence of TD also increases thyroid dysfunction also depends on the glycaemic control of the patients. Out of 67 patients 22 patients had>8.0 HbA1C level. In our study we found that as the glycaemic control became poorer the prevalence of TD increase in hypothyroid but not in hyperthyroidism.Conclusions: Following conclusions were drawn from this study TD is more common in female than male, more after the age of 50 year, in T2DM patients. Hypothyroidism is more common with poor glycaemic control and long duration of T2DM patients. But for hyperthyroidism data which we evaluated was not significant and further conclusion bigger study is needed.

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confidence: 99%

Study of thyroid dysfunction in type 2 diabetes mellitus

2020

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“…There is a great variability in the prevalence of Td in general population, ranging from 6.6% to 13.4%. 15 Screening of TD, especially the subclinical dysfunction, in patients with DM is justified because most patients can be asymptomatic. Determining the prevalence of clinical and subclinical thyroid disease in diabetic patients in our country and its implications in the course of diabetes and known factors for cardiovascular risk shall be an advantage in the management of type 2 DM.…”

Section: Discussionmentioning

confidence: 99%

Subclinical Hypothyroidism- An Undermined Aetiology for Uncontrolled Diabetes Mellitus Type II

Chauhan¹,

Wahane²,

Tyagi³

2019

jebmh

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BACKGROUND Type 2 diabetes and thyroid disorders are the two most common endocrinopathies. 1 Several studies have demonstrated relationship between DM type 2 and thyroid dysfunction, but there are only a few studies done to evaluate the association between subclinical hypothyroidism and glycaemic control of the diabetic patients. METHODS It was a cross sectional case control study in 100 diabetic patients out of which 50 cases had poor glycaemic control and 50 controls were patients with good glycaemic control. Subclinical hypothyroidism was defined as elevated TSH (>4 mIU/L) with normal free T4 and in absence of any clinical features. RESULTS 50 age and sex matched diabetics with HbA1c >6.5 were compared with diabetics with HbA1c <6.5 for thyroid abnormalities. 15% uncontrolled diabetic male and 30% of uncontrolled females had subclinical hypothyroidism compared to 0% male and 11% female with HbA1c <6.5. This when compared to hypothyroid frequency among case and control groups was found to be 5% males and 3.3% females compared to 0% and 3.7% in control group respectively. The frequency of hyperthyroidism was 5% and 6.7% in male and females of case group compared to 4.3% and 3.7% in male and female of control group. CONCLUSIONS The prevalence of subclinical hypothyroidism was more in the group with poor glycaemic control as compared to patients with HbA1c <6.5. Diabetics with poor control have an underlying subclinical hypothyroidism which may accentuate impaired glycaemic control and vice versa.

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“…Thyroid diseases are also common in the general population. There is a great difference in the prevalence of the thyroid diseases in the general population, ranging from 6.6% to 13.4% [3,4]. Large scale studies of thyroid dysfunction in the United States have reported prevalence of 6.6% in the general population [5,6].…”

Section: Introductionmentioning

confidence: 99%

Thyroid Diseases in Omani Type 2 Diabetics: A Retrospective Cross-Sectional Study

Alsumry

Al-Ghelani

Al-Badi

et al. 2015

Advances in Endocrinology

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Background. Diabetes mellitus and thyroid diseases are common endocrine disorders in the general population and found to exist simultaneously. This study aimed to establish the prevalence of thyroid dysfunction among Omani type 2 diabetics and its association with glycemic control. Methodology. A retrospective cross-sectional randomized primary and secondary care based study of 285 Omani type 2 diabetics, ≥ 30 years of age with known thyroid function. The following parameters were examined: age, sex, duration of diabetes, duration of thyroid disease, thyroid morphology, thyroid function, thyroid antibodies, and the mean glycated hemoglobin (mean HbA1C). The prevalence of thyroid dysfunction was compared to an independent control group of randomly selected healthy individuals with known thyroid function. Results. Thyroid dysfunction was found in 12.6% of the diabetic patients compared to 4.9% in the control group. The prevalence was higher among the diabetic females (86%) compared to diabetic males (14%). The commonest thyroid dysfunction among diabetics was overt hypothyroidism (4.6%). Subclinical hypothyroidism was the commonest thyroid dysfunction seen in less controlled diabetics at a mean HbA1c of 7.8 (± 0.7). Conclusion. Screening for thyroid dysfunction in patients with type 2 diabetes mellitus should be routinely performed considering the higher prevalence of thyroid diseases in this group compared to the general population.

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Importância da avaliação da função tireoidiana em pacientes com diabetes mellitus

Cited by 10 publications

References 6 publications

Study of thyroid dysfunction in type 2 diabetes mellitus

Study of thyroid dysfunction in type 2 diabetes mellitus

Subclinical Hypothyroidism- An Undermined Aetiology for Uncontrolled Diabetes Mellitus Type II

Thyroid Diseases in Omani Type 2 Diabetics: A Retrospective Cross-Sectional Study

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