Estadiamento do carcinoma diferenciado de tireóide pela classificação AJCC/TNM

Rosário, Pedro Weslley; Barroso, Álvaro Luís; Padrão, Eduardo L.; Rezende, Leonardo Lamego; Purisch, Saulo

doi:10.1590/s0004-27302004000400021

Cited by 2 publications

(5 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is growing evidence that a cut-off age of 45 years has led to overstaging in many DTC patients, and the use of a cut-off age of 55 years in the 8 th edition of the TNM ® staging system may prevent staging in low-risk patients. This new classification may also provide a more realistic assessment of disease mortality in high-risk patients 3 . A significant number of patients aged 45-55 years can be reclassified to stage I or II with application of the TNM ® 8 th edition 3 .…”

Section: Discussionmentioning

confidence: 99%

“…This new classification may also provide a more realistic assessment of disease mortality in high-risk patients 3 . A significant number of patients aged 45-55 years can be reclassified to stage I or II with application of the TNM ® 8 th edition 3 . In this study, there was a statistical relationship between age >55 years and presence of malignant disease (p=0.0422), indicating that this change in age group may avoid less aggressive therapies in younger patients because of the better prognosis of thyroid cancer at earlier ages.…”

Section: Discussionmentioning

confidence: 99%

“…A disadvantage of using different prognostic systems is that it hinders the application of study conclusions in populations classified differently, as well as the grouping of data in review and consensus articles or metaanalyses 3 . The TNM 8 th edition maintains the worldwide acceptability of the traditional TNM ® staging paradigm, and seems to be satisfactory 4 .…”

Section: /9mentioning

confidence: 99%

“…Disease prognosis can be assessed by a wide range of risk stratification and staging systems, such as MACIS (distant metastasis, age, completeness of primary tumor resection, local invasion, tumor size), AMES (age, distant metastasis, tumor extent, tumor size), AGES (age, grade, tumor extent, tumor size), and TNM ® (tumor, node metastasis, distant metastasis) 3 . The last system 2/9 THYROID DISEASES Impact of TNM® 8 th edition on thyroid cancer retrospective staging was developed in France by Pierre Denoix in 1940, and is currently the most used globally for the treatment, study, and research of malignant neoplasms.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Impact of TNM® 8th edition on thyroid cancer retrospective staging

Daronch¹,

Ahumada²

2022

Arch. Head Neck Surg.

View full text Add to dashboard Cite

Introduction:Thyroid carcinoma has a global survival close to 97% in 15 years. The 8 th TNM ® has recently been proposed, with changes that include an increase in the cut-off age from 45 to 55 years, a change in the role of microscopic extra-thyroidal tumor invasion (which is no longer considered a criterion for the classification of T3 tumors), and the presence of cervical metastases as a criterion for staging. As a result, a large proportion of patients are transferred to earlier stages. Methods: Retrospective descriptive cross-sectional study carried out through analysis of the medical records of patients undergoing thyroidectomy at HC-UFPR from January 2014 to December 2017. Inclusion criteria were patients with a postoperative pathological anatomic diagnosis of well-differentiated thyroid carcinoma (DTC) who underwent primary surgery in the study period. Results: 197 patients underwent thyroidectomy during the period considered, 58 with thyroid neoplasia and 34 with DTC. Eight patients had lymph node metastasis, five (14.70%) as N1a and three (8.83%) as N1b. Of the total sample, six (12.5%) patients presented downstaging from the 7 th to the 8 th edition of the TNM ® . One of the re-staged patients had bone metastasis during follow-up and died during surgery to correct a pathological fracture. Conclusion: In this study sample, the update of the TNM ® in its 8 th edition resulted in the downstaging of six (12.5%) patients with DTC. A longer follow-up and a larger sample are necessary to correctly assess the impact of this change on patient prognosis.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: /9mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Impact of TNM® 8th edition on thyroid cancer retrospective staging

Daronch¹,

Ahumada²

2022

Arch. Head Neck Surg.

View full text Add to dashboard Cite

show abstract

“…In recent years, the search for factors which can influence prognosis has been a constant, since they impact directly on the identification of patients who have a more aggressive disease, as well as its treatment and follow up 8 . Multiple series of cases have been assessed and numerous staging classifications have been proposed taking into account risk and prognostic factors (TNM, EORTC, UICC/AJCC, AGES, AMES, MACIS, Clinical classification, Ohio) 3, 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 . Nonetheless, the relative impact of each one of these indicators is yet to be clearly defined.…”

Section: Introductionmentioning

confidence: 99%

A presença de tireoidite linfocitária crônica influencia o estadiamento tumoral do carcinoma diferenciado da tireoide?

Nemetz¹,

Thomazelli

Granero

et al. 2011

Braz. j. otorhinolaryngol. (Impr.)

View full text Add to dashboard Cite

The association between differentiated thyroid carcinoma (DTC) and chronic lymphocytic thyroiditis (CLT) has been reported in literature. Aim:To evaluate the incidence of this association and to determine whether the CLT may influence on the early initial staging of DTC when associated with other variable risks.Study design: Historical (retrospective) cohort. Materials and Methods:Fifty two patients with DTC were evaluated from 1999 to 2009. They were divided into two groups. The first group had 35 patients with DTC without DLT; the second had 17 patients with CLT. Total thyroidectomy was the treatment chosen for all patients. Similarities shared in both groups such as age, gender, histological tumor type, tumor diameter, regional only or with distant metastases, extrathyroidal invasion, multifocality and presence of tumor capsule were considered. T-Student tests and Chi-square tests were applied to analyze the data. Results:The incidence of DTC without CLT was higher that of DTC+CLT (p=0.0126). We noticed no statistic differences between the common variables analyzed. Conclusions:CLT occurred in 33% of the patients with DCT. All cases of DTC were in the early stages. Braz J Otorhinolaryngol. 2011;77(1):77-83. BJORL ORIGINAL ARTICLE

show abstract

Estadiamento do carcinoma diferenciado de tireóide pela classificação AJCC/TNM

Cited by 2 publications

References 2 publications

Impact of TNM® 8th edition on thyroid cancer retrospective staging

Impact of TNM® 8th edition on thyroid cancer retrospective staging

A presença de tireoidite linfocitária crônica influencia o estadiamento tumoral do carcinoma diferenciado da tireoide?

Contact Info

Product

Resources

About