Revisitando o Hirsutismo

Spritzer, Poli Mara

doi:10.1590/s0004-27302002000200003

Cited by 5 publications

(3 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…According to a review by Spritzer, 29 women with hirsutism—which is highly prevalent among women with PCOS—experience marked psychosocial discomfort that leads to conflicts that compromise their quality of life; we observed this situation in the present study as well.…”

Section: Discussionsupporting

confidence: 74%

Assessment of symptoms of urinary incontinence in women with polycystic ovary syndrome

Montezuma

Antônio

Silva

et al. 2011

Clinics

View full text Add to dashboard Cite

OBJECTIVES:The pelvic floor muscles are sensitive to androgens, and due to hyperandrogenism, women with polycystic ovary syndrome can have increased mass in these muscles compared to controls. The aim of this study is to compare reports of urine leakage and quality of life between women with and without polycystic ovary syndrome.METHODS:One hundred thirteen 18- to 40-year-old nulliparous women with polycystic ovary syndrome or without the disease (controls) were recruited at the University Hospital of School Medicine of São Paulo University at Ribeirão Preto City, Brazil. The subjects were not taking any hormonal medication, had not undergone previous pelvic surgery and did not exercise their pelvic floor muscles. The women were divided into the following four groups: I- polycystic ovary syndrome with normal body mass index (n = 18), II- polycystic ovary syndrome with body mass index ≥25 (n = 32), III- controls with normal body mass index (n = 29), and IV- controls with Body Mass Index ≥25 (n = 34). Quality of life was evaluated using the SF-36 questionnaire, and the subjects with urinary complaints also completed the International Consultation on Incontinence Questionnaire Short Form to evaluate the severity of their urinary incontinence.RESULTS:The replies to the International Consultation on Incontinence Questionnaire Short Form revealed a significant difference in urinary function between groups, with 24% of the subjects in group IV reporting urinary incontinence. The mean scores for the SF-36 questionnaire revealed that group II had the lowest quality of life.CONCLUSIONS:The control obese group (IV) reported a higher prevalence of urinary incontinence. There was no difference in the reported frequency of urine loss between the polycystic ovary syndrome and control groups with normal body mass index or between the polycystic ovary syndrome and control groups with body mass index ≥25.

show abstract

Section: Discussionsupporting

confidence: 74%

Assessment of symptoms of urinary incontinence in women with polycystic ovary syndrome

Montezuma

Antônio

Silva

et al. 2011

Clinics

View full text Add to dashboard Cite

show abstract

“…It is the most common cause of infertility due to anovulation. In many countries, it represents the leading cause of female infertility [2]. The specific pathophysiology of this syndrome has not yet been established, however it is associated with the presence of insulin resistance, obesity, diabetes mellitus type 2, dyslipidemia, metabolic syndrome, hypertension, cardiovascular disease, hyperplasia and endometrial carcinoma [3].When it is considered in the presence of menstrual disorder, diagnosis of PCOS is obtained in 30% -40% of patients with primary or secondary amenorrhoea and in 80% of patients with oligomenorrhea [4] [5].…”

Section: Introductionmentioning

confidence: 99%

Polycystic Ovary Syndrome (PCOS) and Fertility

Barbosa¹,

Sá²,

Rocha³

et al. 2016

OJEMD

View full text Add to dashboard Cite

The polycystic ovary syndrome (PCOS) is defined as a combination of hyperandrogenism (hirsutism and acne) and anovulation (oligomenorrhea, infertility, and dysfunctional uterine bleeding), with or without the presence of polycystic ovaries on ultrasound. It represents the main endocrine disorder in the reproductive age, affecting 6% -15% of women in menacme. It is the most common cause of infertility due to anovulation, and the main source of female infertility. When in the presence of a menstrual disorder, the diagnosis of PCOS is reached in 30% -40% of patients with primary or secondary amenorrhoea and in 80% of patients with oligomenorrhea. PCOS should be diagnosed and treated early in adolescence due to reproductive, metabolic and oncological complications which may be associated with it. Treatment options include drugs, diet and lifestyle improvement.

show abstract

“…O quadro clínico é variável, mas em geral apresenta-se com hirsutismo e/ou acne ou alopecia androgênica, anovulação crônica associada a distúrbio menstrual do tipo oligo/amenorréia e infertilidade. Em 30 a 60% dos casos, em especial nas pacientes obesas, a resistên-cia insulínica e hiperinsulinemia compensatória estarão presentes (6)(7)(8).…”

Section: Síndrome Dos Ovários Policísticos (Pcos)unclassified

Aspectos neuroendócrinos na síndrome dos ovários policísticos

Nácul

Comim

Spritzer

2003

Arq Bras Endocrinol Metab

Self Cite

View full text Add to dashboard Cite

Arq Bras Endocrinol Metab vol 47 nº 4 Agosto 2003 432 RESUMOA síndrome dos ovários policísticos (PCOS) é a endocrinopatia mais freqüente na mulher em idade reprodutiva. O quadro clínico é variável, mas em geral apresenta-se com hirsutismo, acne e/ou alopecia androgênica, anovulação crônica associada a distúrbio menstrual e infertilidade. A resistência insulínica pode estar presente em mais da metade dos casos, em especial nas pacientes obesas. A etiopatogenia ainda não foi totalmente esclarecida, mas mecanismos neuroendócrinos vêm sendo estudados nos últimos anos. Embora esteja bem estabelecida a presença de secreção inapropriada do eixo GnRH-LH em pacientes com PCOS, algumas delas, especialmente as obesas/hiperinsulinêmicas, exibem níveis normais de LH e uma atenuação de sua resposta aos testes de estímulo. Recentemente, descrevemos uma correlação negativa entre leptina e LH em pacientes com PCOS, sugerindo que a atenuação nos níveis de LH nestas pacientes possa estar relacionada a um estado de resistência à leptina. Por outro lado, evidências sugerem que o eixo somatotrófico participe também dos mecanismos fisiopatológicos envolvidos na PCOS. Dados recentes do nosso grupo demonstram que pacientes de peso normal e normoinsulinêmicas apresentam uma maior resposta do GH à clonidina do que pacientes com hirsutismo idiopático. Um mecanismo possível seria uma ação co-gonadotrófica do GH, contribuindo para o hiperandrogenismo clínico e a anovulação. Outra possibilidade é que a elevação da secreção de GH seja somente um epifenômeno vinculado ao aumento de androgênios ovarianos e sua conversão periférica em estrogênios. Estudos futuros são necessários para esclarecer os mecanismos subjacentes associados às alterações descritas neste trabalho e sua relevân-cia na etiopatogenia, diagnóstico e tratamento desta síndrome. Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age. PCOS is a heterogeneous clinical condition, characterized by hirsutism, acne and/or androgenetic alopecia, irregular menstrual cycles and infertility. Moreover, a considerable percentage of PCOS women present insulin resistance, in particular those with obesity. The pathogenesis of the syndrome is still unclear, but neuroendocrine mechanisms have been studied in the last years. Although an inappropriate GnRH/LH secretion is well established, some obese and hyperinsulinemic women with PCOS present an attenuation of these neuroendocrine abnormalities. Recently, we described a negative correlation between leptin and LH levels in PCOS patients, suggesting that the attenuation in basal or stimulated response of LH in obese PCOS patients might be related to a leptin-resistant state. On the other

show abstract

Revisitando o Hirsutismo

Cited by 5 publications

References 34 publications

Assessment of symptoms of urinary incontinence in women with polycystic ovary syndrome

Assessment of symptoms of urinary incontinence in women with polycystic ovary syndrome

Polycystic Ovary Syndrome (PCOS) and Fertility

Aspectos neuroendócrinos na síndrome dos ovários policísticos

Contact Info

Product

Resources

About