Cinnabarin synthesis by Pycnoporus sanguineus strains and antimicrobial activity against bacteria from food products

Smânia, Elza de Fátima Albino; Júnior, Artur Smânia; Loguercio-Leite, Clarice

doi:10.1590/s0001-37141998000400017

Cited by 16 publications

(19 citation statements)

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“…Biformin (37) is produced by Trichaptum biforme (as Polyporus biformis) and is active against a wide variety of bacteria and fungi. 33 The aromatic acetylene derivatives frustulosin (38) and frustulosinol (39) isolated from the liquid cultures of Stereum frustulosum were active against several bacteria such as S. aureus, Bacillus mycoides, and B. subtilis and also moderately active against Vibrio cholera and V. cholera phage. 34,35 Another example of an acetylenic compound exhibiting antifungal activity is the 1-hydroxy-2-nonyn-3-one (40) isolated from the fermentation of the polypore Ischnoderma benzoinum.…”

Section: Antimicrobial Metabolites (Antibacterial and Antifungal)mentioning

confidence: 99%

“…B. cereus and Leuconostoc plantarum were the most sensitive to cinnabarin, each being inhibited with an MIC value of 62.5 µg/mL. 37,38 A large group of antimicrobial secondary metabolites isolated from polypores also includes a cyclodepsipeptide, beauvericin (42). Beauvericin (42) is produced by the bright yellow polypore Laetiporous sulphureus (as Polyporus sulphureus), commonly known as "Chicken-of-the-Woods".…”

Section: Antimicrobial Metabolites (Antibacterial and Antifungal)mentioning

confidence: 99%

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Biologically Active Compounds from Aphyllophorales (Polypore) Fungi

2004

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This review describes biologically active natural products isolated from Aphyllophorales, many of which are known as polypores. Polypores are a large group of terrestrial fungi of the phylum Basdiomycota (basidiomycetes), and they along with certain Ascomycota are a major source of pharmacologically active substances. There are about 25 000 species of basidiomycetes, of which about 500 are members of the Aphyllophorales, a polyphyletic group that contains the polypores. Many of these fungi have circumboreal distributions in North America, Europe, and Asia and broad distributions on all inhabited continents and Africa; only a small number of the most common species with the most obvious fruiting bodies (basidiocarps) have been evaluated for biological activity. An estimated 75% of polypore fungi that have been tested show strong antimicrobial activity, and these may constitute a good source for developing new antibiotics. Numerous compounds from these fungi also display antiviral, cytotoxic, and/or antineoplastic activities. Additional important components of this vast arsenal of compounds are polysaccharides derived from the fungal cell walls. These compounds have attracted significant attention in recent years because of their immunomodulatory activities, resulting in antitumor effects. These high molecular weight compounds, often called biological response modifiers (BRM), or immunopotentiators, prevent carcinogenesis, show direct anticancer effects, and prevent tumor metastasis. Some of the protein-bound polysaccharides from polypores and other basidiomycetes have found their way to the market in Japan as anticancer drugs. Finally, numerous compounds with cardiovascular, phytotoxic, immunomodulatory, analgesic, antidiabetic, antioxidant, insecticidal, and nematocidal activities, isolated from polypores, are also presented. In fact many of the fungi mentioned in this paper have long been used in herbal medicine, including polypores such as Ganoderma lucidum (Reishi or Ling Zhi), Laetiporus sulphureus (Chicken-of-the-Woods), Trametes versicolor (Yun Zhi), Grifola umbellata (Zhu Lin), Inonotus obliquus (Chaga), and Wolfiporia cocos (Hoelen).

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Section: Antimicrobial Metabolites (Antibacterial and Antifungal)mentioning

confidence: 99%

Section: Antimicrobial Metabolites (Antibacterial and Antifungal)mentioning

confidence: 99%

Biologically Active Compounds from Aphyllophorales (Polypore) Fungi

2004

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“…and Phellinus spp., D. caperata and E. scabrosa to inhibit bacterial growth was reported in literature (Smânia et al 1995, 1998, Gogavekar et al 2014, Silva et al 2009, Silva & Jorge 2011, Kalyoncu et al 2010, Wisbeck & Robert 2002. However, the samples used in the current study showed weak or no inhibitory activity against the tested bacteria (Table 1, 4).…”

Section: Discussionmentioning

confidence: 97%

Antibacterial activity of Ethyl Acetate Extract of Agaricomycetes collected in Northeast Brazil

Ferreira-Silva¹

2017

CREAM

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Agaricomycetes produce bioactive substances with antibiotic, antiallergic, antiinflammatory, antioxidant, cytotoxic, antiatherogenic, hepatoprotective, hypoglycemic antiimmunoprotective properties. However, there have been few studies on material collected in Brazil. Thus, the current study aimed to improve the knowledge concerning the antibacterial potential of Agaricomycetes in the country by researching material collected in Northeast Brazil. Twenty one cultures deposited in Micoteca URM of UFPE and nine extracts from fresh basidiomata were tested. Extracts of the basidiomata and the cultures were obtained with ethyl acetate, which were solubilized at a concentration (1:10 v/v). The preliminary tests with the 30 samples (21 cultures and nine extracts of fresh basidiomata) were performed against eleven strains of Staphylococcus aureus, seven of which were resistant to oxacillin (ORSA), using block agar. Thirteen samples showed antibacterial activity, with inhibition between 9-24 mm and minimum inhibitory concentration (MIC) from 0.18-147 µg/mL, Fomitopsis cupreorosea (URM 6830), Ganoderma multiplicatum (URM 6975), G. parvulum (URM 2948), G. orbiforme (URM87741), Grammothele lineata (URM6827), Rigidoporus lineatus (URM 6828), R. microporus (URM 6878), Stereum ostrea (URM 6973, URM 87848) being the most significant.

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“…They are involved in cinnabarinic acid synthesis in P. cinnabarinus (Eggert et al, 1995) and in cinnabarin in Pycnoporus sanguineus (Smânia et al, 1998), which both have an antimicrobial effect. Laccases are also involved in fructification, sporulation and phytopathogenicity of fungi (Gianfreda et al, 1999).…”

Section: B Laccasesmentioning

confidence: 99%