High rate of abnormal glucose tolerance in Brazilian individuals undergoing coronary angiography

Piveta, Valdecira Maria; Giuffrida, Fernando de Mello Almada; Bittencourt, Célia; Oliveira, Carolina Soares Viana de; Saddi-Rosa, Pedro; Meira, Deyse Magalhaes; Reis, André

doi:10.1590/2359-3997000000056

Cited by 2 publications

(2 citation statements)

References 16 publications

(7 reference statements)

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“…First, prevalence of prediabetes is high in CAD patients. The pooled prevalence of prediabetes in our included CAD patients for PCI is 33.5%, which is similar to the previous reports [30][31][32]. Second, compared those with normoglycemia at admission, patients with prediabetes have poor prognosis after PCI.…”

Section: Discussionsupporting

confidence: 88%

Prediabetes predicts adverse cardiovascular outcomes after percutaneous coronary intervention: a meta-analysis

Zhao

Guo²,

Shi

2020

Bioscience Reports

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Background: Prediabetes has been related with increased risk of coronary artery disease (CAD). However, the prognostic efficacy of prediabetes for patients receiving percutaneous coronary intervention (PCI) remains undetermined. We aimed to quantitatively evaluate the influence of diabetes on the risks of major adverse cardiovascular events (MACEs) after PCI in a meta-analysis. Methods: Longitudinal follow-up studies evaluating the association between prediabetes and risks of MACEs and mortality after PCI were identified by search of PubMed and Embase databases. A random-effect model was applied to pool the results. Subgroup analyses were performed to evaluate the impacts of study characteristics on the outcome. Results: Twelve follow-up studies including 10,048 patients that underwent PCI were included. Compared with patients with normoglycemia at admission, those with prediabetes were had significantly higher risk MACEs during follow-up (adjusted risk ratio [RR]: 1.53, 95% confidence interval [CI]: 1.25–1.87, P < 0.001). Further subgroup analyses indicated that the association between prediabetes and higher risk of MACEs remained regardless of the study design, sample size, CAD subtype, PCI type, definition of diabetes, or follow-up duration. Moreover, patients with prediabetes had higher significantly risk of MACEs in studies with adjustment of coronary lesion severity (RR: 1.79, P < 0.001), but the association became insignificant in studies without adjustment of the coronary lesion severity (RR: 1.23, P = 0.09). Conclusions: Prediabetes is independently associated with increased risk of MACEs after PCI as compared with those with normoglycemia, even in studies with adjustment of coronary severity.

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Section: Discussionsupporting

confidence: 88%

Prediabetes predicts adverse cardiovascular outcomes after percutaneous coronary intervention: a meta-analysis

Zhao

Guo²,

Shi

2020

Bioscience Reports

View full text Add to dashboard Cite

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“…One study estimated that the incidence of prediabetes was ∼ 32.3/1000 personyears [3]. Also, a prevalence rate of prediabetes of up to 65% has been reported in patients admitted for selective coronary angiography [4].…”

Section: Introductionmentioning

confidence: 99%

Two-dimensional speckle-tracking echocardiography evaluation of left atrial function according to glycemic state in patients with coronary artery disease

Hosseinsabet

Mohseni-Badalabadi

Jalali

2017

Cardiovascular Endocrinology

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Objectives Prediabetes and diabetes are dysglycemic conditions associated with increased cardiovascular risks and subtle myocardial injuries. The aim of our study was to evaluate left atrial (LA) function by two-dimensional speckle-tracking echocardiography in prediabetic and diabetic patients with coronary artery disease (CAD) and compare the results with those in euglycemic patients with CAD.Methods The study population comprised 205 consecutive patients with CAD: 104 diabetic, 51 prediabetic, and 50 euglycemic patients. LA function was evaluated with twodimensional speckle-tracking echocardiography and the longitudinal deformation indices of the LA were measured. ResultsOur results showed that early diastolic strain was lower in the diabetic patients than in the prediabetic and euglycemic patients. The absolute value of early diastolic strain rate was reduced in the diabetic patients compared with the euglycemic patients. Late diastolic strain was increased in the diabetic patients compared with the prediabetic and euglycemic patients. The multivariate analysis showed that diabetes was a determinant of early diastolic strain and strain rate, but not late diastolic strain.Conclusion LA conduit function, as evaluated in terms of early diastolic strain and strain rate, was impaired in the diabetic CAD patients compared with the prediabetic and euglycemic CAD patients.

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High rate of abnormal glucose tolerance in Brazilian individuals undergoing coronary angiography

Cited by 2 publications

References 16 publications

Prediabetes predicts adverse cardiovascular outcomes after percutaneous coronary intervention: a meta-analysis

Prediabetes predicts adverse cardiovascular outcomes after percutaneous coronary intervention: a meta-analysis

Two-dimensional speckle-tracking echocardiography evaluation of left atrial function according to glycemic state in patients with coronary artery disease

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