Exposição ao benzeno no trabalho e seus efeitos à saúde

Moura-Correa, Maria Juliana; Larentis, Ariane Leites

doi:10.1590/2317-6369ed0000117

Cited by 4 publications

(5 citation statements)

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“…Gas station workers, in general, are exposed to different solvents present in the various types of fuels marketed, in addition to environmental pollution, since the work occurs in open environments [ 29 ]. Filling station attendants, one of the main work forces at these facilities, perform activities such as vehicle filling, checking fuel levels in vehicle storage compartments, and changing vehicle fluids, such as oils, lubricators.…”

Section: Discussionmentioning

confidence: 99%

Analysis of Benzene Exposure in Gas Station Workers Using Trans,Trans-Muconic Acid

Geraldino

Nunes

Gomes

et al. 2020

IJERPH

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In Brazil, gas station workers are occupationally exposed to the benzene present in gasoline. Brazilian law indicates the use of trans,trans-muconic acid(t,t-MA) as a biomarker of benzene exposure. The aim of this study was to evaluate the level of exposure to benzene in gas station workers, through the quantification of t,t-MA present in urine. A total number of 269 gas station workers divided into 179 filling station attendants exposed by inhalation and dermal route and 90 convenience store workers exposed only by inhalation were included. A control group was formed by 100 office workers, without occupational exposure to benzene. The urinary levels of t,t-MA were evaluated by HPLC with a UV detector. Gas station workers showed higher mean values of t,t-MA (0.204 mg/g creatinine; 95% CI 0.170–0.237) than office workers (0.126 mg/g creatinine; 95% CI 0.0817–0.1693). T,t-MA levels were higher in convenience store workers exposed to gasoline only by inhalation (0.221 mg/g creatinine; 95% CI 0.160–0.282), than in those exposed to gasoline by inhalation and dermal route—filling station attendants (0.195 mg/g creatinine; 95% CI 0.155–0.235). Gas station workers with a higher level of t,t-MA had epistaxis. T,t-MA values were higher in the Downtown (0.15 mg/g creatinine) region’s workers than in the more affluent South Zone region’s workers (0.07 mg/g creatinine). Smoking habits influenced the urinary t,t-MA values, while the frequency of consumption of industrialized and frozen foods showed no influence.

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Section: Discussionmentioning

confidence: 99%

Analysis of Benzene Exposure in Gas Station Workers Using Trans,Trans-Muconic Acid

Geraldino

Nunes

Gomes

et al. 2020

IJERPH

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“…It should be noted that apprentices can enter the labor market at the age of 15, but only in non-dangerous occupations; however, this might not be adopted in remote or poor areas. Several initiatives were carried out, such as surveillance by the institutions responsible for the protection of health and work in the occupational and environmental spheres, regulations, the valorization of the participation of workers in risk prevention actions, intervention in territory with exposure, campaigns, information, and risk communication on the carcinogenicity of benzene [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

Leukemia Mortality among Benzene-Exposed Workers in Brazil (2006–2011)

Moura-Corrêa

2023

IJERPH

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Background: In this study, the annual leukemia mortality rate is estimated by occupational groups potentially exposed to benzene in Brazil and compared to non-exposed workers by sex. Methods: Data were extracted from the Mortality Information System and the National Institute of Geography and Statistics from 2006 to 2011. Occupational groups exposed to benzene were defined by using the Finnish Job-Exposure Matrix, FINJEM. Results: We found 21,049 leukemia deaths in 1917 in occupational groups potentially exposed to benzene, corresponding to an annual average mortality rate of 4.5/100,000, higher than the estimate for non-exposed workers: 2.6/100,000, corresponding to a Mortality rate ratio MRR = 1.7. Each benzene-exposed occupational group had increased leukemia mortality, and printers and occupations in graphics presented the highest MRR (2.7), followed by laboratory assistants (MRR = 2.6), laundry workers, chemists, and upholsterers, each of these occupational groups presenting MRR = 2.3. Conclusions: Benzene shows the need for better enforcement of protective norms against this known carcinogen. Our results support the need for better enforcement of protective norms to reduce benzene exposure.

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“…Exposure to hydrocarbons and their derivatives, such as benzene, present in detergents, plastics and gasoline has generated several alerts by the International Agency for Research on Cancer (IARC) about their potential carcinogenic risk [1][2][3][4][5][6][7][8] .…”

Section: Introductionmentioning

confidence: 99%

“…Many of these substances are absorbed by the human body through inhalation, dermal contact or even by ingestion. Especially in relation to benzene, after its absorption, its toxic effects can be detected in the liver (primary metabolism), bone marrow (secondary metabolism) and kidneys (excretion) 2,4,5,7,9,10 .…”

Section: Introductionmentioning

confidence: 99%

Contagem de Reticulócitos e suas Frações Imaturas como Indicador Precoce de Alteração Medular em Trabalhadores de Postos de Combustíveis

Vilhena

Rebelo

Neto

et al. 2023

Rev. Bras. Cancerol.

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Introdução: A exposição ocupacional prolongada a componentes tóxicos da gasolina, como o benzeno, há muito tempo e reconhecida como um importante fator de alterações hematológicas. Objetivo: Avaliar a contagem de reticulócitos e suas frações imaturas (IRF) em amostras de trabalhadores de postos de combustíveis (“frentistas”) atendidos em um laboratório particular de Belém, Pará, no período de janeiro a dezembro de 2021. Método: Foram analisadas 47 amostras de sangue periférico de trabalhadores de postos de combustíveis do sexo masculino (grupo do estudo), independentemente do tempo de atividade laboral, e que realizam exames laboratoriais periódicos em um laboratório particular de Belém, e 47 amostras de clientes, também do sexo masculino, que realizaram hemograma de rotina no mesmo laboratório e não apresentavam doença hematológica prévia (grupo controle). Resultados: No grupo controle, 46/47 (97,9%) das amostras apresentavam média de contagem de reticulócitos de 62.828/mm3 e de IRF relativas de 3/47 (6,4%), já nos trabalhadores do grupo de estudo a média de contagem de reticulócitos foi de 100.628/mm3 e de IRF de 5/47 (10,8%). Destas, 34/47 (72,3%) amostras apresentavam contagem de reticulócitos e de IRF superiores aos valores de referência. Conclusão: Os resultados sugerem que o aumento da contagem de reticulócitos e suas IRF em frentistas de postos de combustíveis podem ser importantes marcadores de risco precoce de intoxicação medular pelo benzeno.

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Exposição ao benzeno no trabalho e seus efeitos à saúde

Cited by 4 publications

References 4 publications

Analysis of Benzene Exposure in Gas Station Workers Using Trans,Trans-Muconic Acid

Analysis of Benzene Exposure in Gas Station Workers Using Trans,Trans-Muconic Acid

Leukemia Mortality among Benzene-Exposed Workers in Brazil (2006–2011)

Contagem de Reticulócitos e suas Frações Imaturas como Indicador Precoce de Alteração Medular em Trabalhadores de Postos de Combustíveis

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