Neglected diseases have been demonstrated over the years as a persisting scourge for excluded population, thus, they have been a bioethical interest. They are classified as a group of infectious diseases, which are strongly linked with the poverty conditions verified in most of low and middle-income countries. In intention to approach two knowledge areas through a dialogue in order to demonstrate that despite being very specific, they can operate synergistically, the main purpose of this dissertation was to analyze quantitative and qualitative the knowledge production of in neglected diseases in Brazil, taking into account normative devices concerning to the topic and the researchers acting area. The present research used public documents and statistical data to obtain the results, which were the inducted actions to neglected diseases became a priority to National Health Researches Priority Agenda which started from Science, Technology and Health Innovation National Politics. 140 projects have been included in two issues. There was an equalization in male and female participation in researches coordination. Most included projects were from higher education institutions and researcher institutions, which were public institutions. Most of the researches became health and science area and concentrated more particularly in institutions from Southeastern region in spite of regions which neglected diseases happened mostly (North, Northeast and Midwest regions). In the first issue, biomedical studies represented the most part of the projects. In second issue, clinical researches were leading the study ranking which were developed by public support. In relation to the researchers' activities analyzed by this dissertation, it happened in biological and individualized focus about the disease, which was hegemonic and through a social and collective focus. The health exponent authors also have shown influence in researchers group analyzed by this dissertation. In spite of iniquities related to the regional distribution of the number of projects and hegemonic focus made, it was concluded that plain of action assumed by Brazilian State and part of national scientific community might been considered as morally justified and ethically compromised. The attitude taken by the country brought to the center of health research attention an issue that, despite relevant to the developing conditions of a nations, has been vilified, especially, by the ones who believes that the people who live in a social vulnerability state might have been denied to the access of a quality health care and medication which are necessary for the survival.