Resistência de bactérias isoladas em equipamentos em unidade de terapia intensiva

Rocha, Igor Vasconcelos; Ferraz, Patrick de Mélo; Farias, Thaísa Gabriela Silva de; Oliveira, Sibele Ribeiro de

doi:10.1590/1982-0194201500073

Cited by 13 publications

(11 citation statements)

References 23 publications

(28 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Inducible resistance to clindamycin was found in D test in 51.8% (14/27) of isolates, which limits its effectiveness as a treatment option in MRSA infections. Therefore, the application of D test in the laboratorial routine is useful to investigated possible clindamycin resistance that helps the clinician in the effective use of clindamycin when this was a therapeutic option 35 .…”

Section: Discussionmentioning

confidence: 99%

Resistance Profile From Staphylococcus Aureus And Pseudomonas Aeruginosa Obtained From Tracheostomized Children

Almeida

Barros

Ayres

et al. 2020

Preprint

View full text Add to dashboard Cite

Background The tracheostomized patients exhibit high risks of bacterial infections, because the tracheal tube acts as a gateway to these microorganisms. The objective was to characterize microbiologically the tracheal secretion of tracheostomized children, to evaluate the biofilm formation, and to study the phenotypic and molecular profile of antimicrobial resistance of Staphylococcus aureus and Pseudomonas aeruginosa isolated. Methods The study collected 88 tracheal secretion samples. The material processed by phenotypic tests were performed for bacterial identification. For identification of the biofilm, the Congo red agar test and the plaque microtiter test were used, and the qPCR method was used to resistance verification. Results Were obtained 27 samples of S. aureus and 71 of P. aeruginosa . All S. aureus samples were positive for biofilm formation on Congo red agar test. In antibiogram test, S. aureus showed resistance to seven drugs. Regarding the identification of resistance genes, were amplificated bla Z in 42.8% from S. aureus and mec A in 28.6% of them. Pseudomonas aeruginosa presented resistance to eight drugs. The most frequent chromosomal genes were bla OXA with 66.7% and bla KPC with 58.3%. To plasmidial DNA, was highlighted bla NDM with 58.3% positive. Conclusion The S. aureus and P. aeruginosa characterization of colonization from lower respiratory tract associated with the use of the device in tracheotomy patients, and the physiology and antimicrobial resistance profile, will help health professionals to choose the most appropriate treatment to be administered in children with tracheotomy, increasing the chances of airway restoration and decannulation.

show abstract

Section: Discussionmentioning

confidence: 99%

Resistance Profile From Staphylococcus Aureus And Pseudomonas Aeruginosa Obtained From Tracheostomized Children

Almeida

Barros

Ayres

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…and Candida auris [8,9]. Drug-resistant pathogens can be transmitted through the hospital environment, increasing the severity in relation to Health Care-Associated Infections (HAIs) [10], also causing an important economic impact especially in developing countries. In these countries, the infectious diseases are more prevalent, and the prevention measures requires the use of drugs that maximize costs [7].…”

Section: Introductionmentioning

confidence: 99%

Light and Phages on Tackle of Infectious Diseases

Cruz¹,

Bogas²,

Sousa³

2021

Bacteriophages in Therapeutics

View full text Add to dashboard Cite

There has been an important increase in the emergence of resistance in microbial population worldwide. This trajectory needs, necessarily new approaches to treat infectious diseases. The ability to detect and prevent the evolutionary trajectories of microbial resistance would be of value. Photodynamic inactivation (PDI) represents an efficient alternative treatment for diseases caused by viruses, which can cause infections well documented in various mammals. PDI can kill cells after exposure with the appropriate photosensitizer (PS), light of adequate wavelength combined with the presence of oxygen, without inducing resistance. Cytotoxic reactive species formed interaction with vital biomolecules leading to irreversible microbial inactivation. Bacteriophages can act on delivering antimicrobial agents into bacteria, which consist in a likely instrument for the treatment of infectious diseases. Non-enveloped bacteriophages are more difficult to tolerate photoinactivation than enveloped phages, which makes them an important model tool to evaluate the efficiency of PDI therapy against viruses that cause diseases in humans. Combination of photosensitizers and bacteriophage therapy can be employed to eradicate biofilms, contributing to control of infections also caused by drug-resistant bacteria.

show abstract

“…13 The tracking of these microorganisms by appropriate methods, should be extended not only to laboratory testing of patients, particularly blood cultures, but also to the environment which the patients rests, like inanimate surfaces near then, given that different resistant organisms have been reported as possible causes of crossinfection. [13][14][15] Nosocomial infections can be controlled through effective measures that interfere with the microorganism transmission process, such as frequent hand washing, proper cleaning of equipment and surfaces of beds, the use of personal protective equipment and the adoption of aseptic measures. 15 This study aimed to evaluate the presence and resistance profile of Staphylococcus aureus and coagulase-negative Staphylococci resistant to oxacillin isolated in surfaces and blood cultures in an Intensive Care Unit of an emergency hospital in the city of Caruaru, Pernambuco, Brazil.…”

mentioning

confidence: 99%

Staphylococcus spp. resistentes em hemoculturas e superfícies hospitalares e a segurança do paciente

Almeida

Silva

Rocha³

et al. 2017

Rev Epidemiol Control Infect

Self Cite

View full text Add to dashboard Cite

Justification and Objectives:This study aimed to evaluate the presence and resistance of Staphylococcus aureus and coagulase-negative Staphylococci resistant to oxacillin isolated in surfaces and blood cultures in an Intensive Care Unit of an emergency hospital in the city of Caruaru, Pernambuco, Brazil. Methods: This is a descriptive, cross-sectional study, the collections being performed from the bed surfaces of an Intensive Care Unit (ICU). In parallel, blood samples from the respective patients were also obtained. Samples were collected by convenience sampling and the identification of the isolated microorganisms was done by mass spectrometry. Results: We observed a higher prevalence of bacteria from the group of coagulasenegative Staphylococci -CoNS (76.92%) in relation to the species Staphylococcus aureus (23.07%). Among the microorganisms identified as resistant to oxacillin, 12.5% of the species were similar in the bed surface samples and blood cultures from the same patient sample. Conclusions: Resistant bacteria identified reinforce the importance of emphasizing the general measures of environmental hygiene in relation to patient safety in health care.

show abstract

Resistência de bactérias isoladas em equipamentos em unidade de terapia intensiva

Cited by 13 publications

References 23 publications

Resistance Profile From Staphylococcus Aureus And Pseudomonas Aeruginosa Obtained From Tracheostomized Children

Resistance Profile From Staphylococcus Aureus And Pseudomonas Aeruginosa Obtained From Tracheostomized Children

Light and Phages on Tackle of Infectious Diseases

Staphylococcus spp. resistentes em hemoculturas e superfícies hospitalares e a segurança do paciente

Contact Info

Product

Resources

About