Cross-sectional associations between cognition and mobility in Parkinson’s disease

Abstract

ABSTRACT. Cross-sectional studies show an association of decline in mental flexibility and inhibitory control with reduced gait speed and falls, as well as divided attention deficit and difficulty in initiating gait. Objective: To investigate the relationships between cognitive function and gait performance in patients with Parkinson’s disease (PD) who participated in a hospital neurorehabilitation program. Methods: A total of 107 patients (79 males, 28 females; mean age 61.00±8.2 years; mean schooling 11.7±4.1 years) with idiopathic PD (mean disease duration 5.5±4.1 years) were recruited for this study. Among them, 78.50% were in stages I and II of the Hoehn & Yahr Scale. Cognitive functions were evaluated through the Digit Span test, Trail Making Test, and Addenbrooke’s Cognitive Examination III. Motor function was assessed with the 10-Meter Walk Test, the short version of the Balance Evaluation Systems Test (Mini-BESTest), and the Timed Up and Go Test. Results: Balance skills were significantly correlated with global cognition and specific domains, including divided attention, verbal fluency, and visuospatial function. Functional mobility showed a significant association with all cognitive tests, except for the number of errors on TMT-A. Gait speed presented a significant correlation with global cognition scores, memory, and attention, including divided attention. Conclusions: These findings might help early identification of cognitive deficits or motor dysfunctions in PD patients who may benefit from rehabilitation strategies, as well as facilitate fall risk assessments and strategies to prevent falls. Future prospective studies are needed to investigate the effects of cognitive training on motor performance, since the difficulty in motor rehabilitation may be more related to cognitive loss than to motor damage.

Evaluation of the properties of WHODAS-12 measurements in individuals with Chagas disease in Brazil

“…This study showed a high internal consistency for WHODAS-12 on the global scale (α = 0.87). Similar Cronbach alpha values were obtained for a Spanish population with depression (0.89) 27 , an Italian population after neurosurgery (0.87) 24 and a general Portuguese population over 55 years old (α = 0.86) 15 . A systematic review of 2019, with 14 studies, reported generally high alpha estimates, ranging from 0.81 to 0.96 16 .…”

“…A participation and cognition item was loaded in factors 1 and 2. Cognition has been described with positive correlations for physical performance, such as balance, mobility and walking 26 , 27 . We believe that cognition can have a positive response in mobility and participation.…”

Bedside nursing care for patients on hemodialysis

“…In this context, considering that most ADLs require the simultaneous performance of two or more tasks, that is, the performance in dual-task, such as walking and talking to someone, sending messages or remembering a shopping list, this can be one of the physiotherapeutic approaches used during the followup of the patient with PD. (DEBLOCK-BELLAMY; LAMONTAGNE; BLANCHETTE, SOUSA;MACEDO;BRUCKI, 2021).…”

The evolution of HIV/AIDS knowledge

“…In this context, considering that most ADLs require the simultaneous performance of two or more tasks, that is, the performance in dual-task, such as walking and talking to someone, sending messages or remembering a shopping list, this can be one of the physiotherapeutic approaches used during the followup of the patient with PD. (DEBLOCK-BELLAMY;LAMONTAGNE;BLANCHETTE, 2020;SOUSA;MACEDO;BRUCKI, 2021).…”