Cross-cultural adaptation of the "Australian National University Alzheimer's Disease Risk Index" for the Brazilian population

Abstract

Alzheimer's disease (AD) represents a major public health problem and it is therefore crucial that modifiable risk factors be known prior to onset of dementia in late-life. The "Australian National University - Alzheimer's Disease Risk Index" (ANU-ADRI) is one of the potential tools for primary prevention of the disease.ObjectiveThe aim of this study was to devise an adapted version of the ANU-ADRI for use in Brazil.MethodsThe instrument was translated from its original language of English into Portuguese and then back-translated into English by bilingual translators. It was subsequently reviewed and evaluated as to the degree of translation issues and equivalence. In this study, the ANU-ADRI was applied using individual (face-to-face) interviews in a public hospital, unlike the original version which is applied online by self-report. The final version (pretest) was evaluated in a sample of 10 participants with a mean age of 60 years (±11.46) and mean education of 11 years (±6.32).ResultsThe intraclass correlation coefficient (ICC) (inter-rater) was 0.954 (P<0.001 for a confidence interval (CI) of 95%=[0.932; 0.969]). Cultural equivalence was performed without the need for a second instrument application step.ConclusionAfter cross-cultural adaptation, the language of the resultant questionnaire was deemed easily understandable by the Brazilian population.

Adaptation of the Australian National University Alzheimer's Disease Risk Index‐Short Form (ANU‐ADRI‐SF) into Turkish

“…Andrews et al (2017) found that the ANU-ADRI score in older adults in Australia was 9.4 (5.9). Borges et al (2017) found that the total score in adults in Portugal was 6.3 (13.8). Park et al ( 2019) reported that the baseline ANU-ADRI risk score for the active control group was 17.6 (7.7) and the protective factor score was −8.3 (3.2).…”

“…Since the correlation coefficient is higher than 0.70, the scale is considered reliable (Karakoç & Dönmez, 2014). The Portuguese ANU‐ADRI, whose conceptual validity was confirmed by expert opinions, was found to be reliable according to the intra‐class correlation coefficient (ICC) (0.95) (Borges et al., 2017). To confirm the extent to which the Australian ANU‐ADRI can predict the risk of AD in older adults, comparison was made with three dementia risk indices developed for middle‐aged groups.…”

“…controlled research protocols to reduce the risk of dementia in primary care (Kim et al, 2018). The ANU-ADRI has been adapted for use in Brazil and has been shown to be valid in Portuguese (Borges et al, 2017). However, a validation study found that the 10-year dementia risk estimates of the ANU-ADRI and other models were too extreme and that they performed similar to age-only predictions (Licher et al, 2018).…”

“…The ANU‐ADRI has also been used in studies to evaluate the efficacy of interventions to reduce lifestyle risk factors for AD (McMaster et al., 2018, 2020; Park et al., 2019), and it has been shown to be a valid and reliable tool in randomised controlled research protocols to reduce the risk of dementia in primary care (Kim et al., 2018). The ANU‐ADRI has been adapted for use in Brazil and has been shown to be valid in Portuguese (Borges et al., 2017). However, a validation study found that the 10‐year dementia risk estimates of the ANU‐ADRI and other models were too extreme and that they performed similar to age‐only predictions (Licher et al., 2018).…”

Avaliação em idosos: uma investigação sobre instrumentos de medida

“…Alguns estudos não informaram de forma objetiva o total da amostra, outros, por serem somente metodológicos, não se aplicava uma amostra. O estudo com maior quantidade amostral brasileira, contou com 5.970 participantes(DAMÁSIO et al, 2016) e o menor, com 10 participantes(BORGES et al, 2017). As discussões sobre o tamanho adequado de uma amostra são inúmeras e muito relevantes para o campo científico.…”