Fatores associados às alterações de equilíbrio em idosos residentes no município de São Paulo em 2006: evidências do Estudo Saúde, Bem-Estar e Envelhecimento (SABE)

Bushatsky, Angela; Alves, Luciana Correia; Duarte, Yeda Aparecida de Oliveira; Lebrão, Maria Lúcia

doi:10.1590/1980-549720180016.supl.2

Cited by 28 publications

(22 citation statements)

References 17 publications

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“…This advanced aging may owe to the discrimination of the feeding environment, similar as the living condition also varies among human from different countries. [ 25 ]…”

Section: Discussionmentioning

confidence: 99%

Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level

Chen

et al. 2021

Molecular Nutrition Food Res

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Scope The muscle loss during aging results from the blunt of protein synthesis and poses threat to the elderly health. This study aims to investigate whether betaine affects muscle loss by improving protein synthesis. Methods and Results Male C57BL/6J mice are raised from age 12 or 15 months. Mice are fed with AIN‐93M diet without or with 2% w/v betaine in distilled water as control group or betaine intervention group (Bet), respectively. Betaine supplementation to mice demonstrates better body composition, grip strength, and motor function. Muscle morphology upregulates expression of myogenic regulate factors, and elevates myosin heavy chain and also improves in Bet group. Betaine promotes muscle protein synthesis via tethering mammalian target of rapamycin complex1 protein kinase (mTORC1) on the lysosomal membrane thereby activating mTORC1 signaling. All these effects aforementioned are time‐dependent (p < 0.05). Ultrahigh‐performance liquid chromatography results show that betaine increases S‐adenosyl‐l‐methionine (SAM) via methionine cycle. SAM sensor—Samtor—overexpression in C2C12 cells could displace mTORC1 from lysosome thereby inhibiting the mTORC1 signaling. Addition of betaine attenuates this inhibition by increasing SAM level and then disrupting interaction of Samtor complex. Conclusions These observations indicate that betaine could promisingly promote protein synthesis to delay age‐related muscle loss.

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“…This advanced aging may owe to the discrimination of the feeding environment, similar as the living condition also varies among human from different countries. [ 25 ]…”

Section: Discussionmentioning

confidence: 99%

Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level

Chen

et al. 2021

Molecular Nutrition Food Res

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“…In older adults, the amplitude, frequency, and postural oscillation in the standing position is also greater than in younger subjects [28]. Declines in balance may be related to the decrease in neuromotor reactions and muscle contraction resulting from aging [29]. The SPPB assesses balance through maintenance of a static position for at least 10 seconds [25,30].…”

Section: Analysis Of Physical Performance Using the Sppbmentioning

confidence: 99%

Short Physical Performance Battery as a Measure of Physical Performance and Mortality Predictor in Older Adults: A Comprehensive Literature Review

Silva

Ohara

Matos

et al. 2021

IJERPH

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The association between the Short Physical Performance Battery (SPPB) score and several adverse health outcomes, including mortality, has been reported in the scientific literature. We conducted a comprehensive literature review of studies on the relationship between SPPB and mortality. The current paper synthesizes the characteristics and main findings of longitudinal studies available in the literature that investigated the role of the SPPB in predicting mortality in older adults. The studies (n = 40) are from North America, South America, Europe, and Asia; the majority (n = 16) were conducted with community-dwelling older adults and reported an association between lower SPPB scores and a higher risk of mortality, and between higher SPPB scores and higher survival. Nevertheless, few studies have analyzed the accuracy of the instrument to predict mortality. The only study that established cut-off points was conducted with older adults discharged from an acute care hospital. Although an SPPB score lower than 10 seems to predict all-cause mortality, further studies showing cut-off points in specific settings and loco-regional specificities are still necessary.

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“…Porém, o resultado da variável equilíbrio apresentou um índice baixo com média de 8,90, não condizente com a literatura, onde no estudo de Bushatsky et al 34 relataram uma média de 14. Percebe-se que alguns idosos sofrem uma grande alteração em seu equilíbrio podendo assim interferir em suas atividades diárias.…”

Section: Discussionunclassified

[Id 55938] Correlação Do Equilíbrio E Qualidade De Vida De Idosos De Um Centro Social Em Belém-Pa

Santos¹,

Carvalho²,

Sobral³

et al. 2021

RBCS

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Objetivo: Correlacionar o equilíbrio e a qualidade de vida dos idosos de um Centro Social em Belém – PA. Metodologia: O presente estudo foi observacional, descritivo e analítico, do tipo transversal. A amostra foi composta por 80 idosos, utilizando-se como instrumentos para a coleta dos dados, uma ficha de avaliação fisioterapêutica, a escalda de Tinetti, para avaliar o equilíbrio e o questionário SF-36, para avaliar a qualidade de vida. Utilizou-se os testes do Qui-quadrado, teste G (aderência) e correlação de Spearman para análise estatística. Resultados: Os resultados obtidos na amostra dos indivíduos idosos mostraram que ocorreu um predomínio do sexo feminino, com risco moderado de queda, com boa percepção da qualidade de vida para a saúde mental e pior percepção para os aspectos físicos. No entanto, todos os domínios da SF-36 correlacionaram positivamente com o equilíbrio. Conclusão: Diante dos resultados obtidos neste estudo, pode-se observar que os idosos apresentaram alterações no equilíbrio e na marcha e resultados satisfatórios nos domínios: saúde mental, aspectos sociais e vitalidade na escala de qualidade de vida, ensejando que a qualidade de vida está diretamente relacionada com o equilíbrio dos idosos, ou seja, quanto melhor o equilíbrio melhor é a percepção da qualidade de vida.

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Fatores associados às alterações de equilíbrio em idosos residentes no município de São Paulo em 2006: evidências do Estudo Saúde, Bem-Estar e Envelhecimento (SABE)

Cited by 28 publications

References 17 publications

Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level

Betaine Delayed Muscle Loss by Attenuating Samtor Complex Inhibition for mTORC1 Signaling Via Increasing SAM Level

Short Physical Performance Battery as a Measure of Physical Performance and Mortality Predictor in Older Adults: A Comprehensive Literature Review

[Id 55938] Correlação Do Equilíbrio E Qualidade De Vida De Idosos De Um Centro Social Em Belém-Pa

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