Factors associated with lip and oral cavity cancer

Abstract

ABSTRACT:Purpose: This study aimed to identify factors associated with the occurrence of primary cancer of the lip and oral cavity regions compared to other types of head and neck cancers according to demographic, socioeconomic data and lifestyle, in Brazil, from 2000 to 2011. Methods: A study was conducted using Hospital Cancer Records (Instituto Nacional do Câncer), from 2000 to 2011, totaling 23,153 cases. Data were analyzed by binary logistic regression (response category: primary cancers located in the lip and oral cavity; comparison category; other types of primary cancer in the head and neck, which does not affect the lip and oral cavity) at a significance level α = 5%. Results: The study showed factors associated with higher incidence of cancer in the lip and oral cavity: being of advanced age (OR = 1.16), not having a family history of cancer (OR = 2.38), alcohol consumption (OR = 1.17); former tobacco use (OR = 1.51) or current tobacco use (OR = 1.65); having a previous diagnosis of cancer without treatment (OR =1.66). Being female (OR = 0.92), having completed basic (OR = 0.71) and higher (OR = 0.46) education and having previous diagnosis of cancer with treatment (OR = 0.74) constituted factors associated with lower prevalence of cancer of the lip and oral cavity. Conclusion: Age, absence of family history of cancer, smoking habits and alcohol consumption, and previous diagnosis of cancer without treatment were associated with a higher incidence of cancer of the lip and oral cavity.

Epidemiology, incidence and mortality of oral cavity and lips cancer and their relationship with the human development index in the world

“…The concern about lip and oral cavity area is related to high incidence of malignant tumors in this areas compared to other areas of head and neck. complications and mortality which occur from squamous cell carcinoma diagnosis which is a the diagnosed tissue, that can be found 40% in lip and oral cavity, 25% in the larynx and 15%in the throat with a low incidence in oral area (Ribeiro et al, 2015). In addition, oral cancer disease burden is high due to the high cost of treatment, permanent impairment and mortality (Rao et al, 2013).…”

“…Smoking, alcohol consumption, sun exposure and viral infections, previous events of head and neck cancer and socioeconomic status can be related to the occurrence of lip and oral cavity cancer (Ribeiro et al, 2015).In most countries of the world, oral cancer occurs more in men than in women. Differences in gender is due to differences in indulgence in risk full behavior habits (tobacco and alcohol) by men and prolonged exposure to sunlight (lip cancer) (Warnakulasuriya, 2010).Lip cancer in white people is more than black people (Wurman et al, 1975).…”

The incidence and mortality of lip and oral cavity cancer and its relationship to the 2012 Human Development Index of Asia

“…Although lip and oral cavity cancer accounts for less than 3% of all cancer cases worldwide, its low survival rate and adverse consequences on quality of life have garnered it to be considered as a significant public health problem; in fact, two thirds of its burden occurs in developing countries (Costa et al, 2016;Farah et al, 2014;Global Burden of Disease Cancer, 2015;Ribeiro et al, 2015;Torre et al, 2015;Warnakulasuriya, 2009 Since people who live in developing countries are exposed to a wider range of risk factors for cancer of the lip and oral cavity, the highest incidence rates are reported from these countries (Byakodi et al, 2012;de Camargo Cancela et al, 2010;Gupta et al, 2016;Rastogi et al, 2004). The most important risk factors of this cancer are tobacco use, alcohol, chewing tobacco, betel quid, poor eating habits, sun exposure, viral infections (especially HPV), and poor oral hygiene (de Camargo Cancela et al, 2010;Farah et al, 2014;Funk et al, 2002;Ribeiro et al, 2015;Warnakulasuriya, 2009).…”

“…The most important risk factors of this cancer are tobacco use, alcohol, chewing tobacco, betel quid, poor eating habits, sun exposure, viral infections (especially HPV), and poor oral hygiene (de Camargo Cancela et al, 2010;Farah et al, 2014;Funk et al, 2002;Ribeiro et al, 2015;Warnakulasuriya, 2009). In India and Pakistan, about 100 million people use various types of smokeless tobacco and betel-quid chewing (Jayalekshmi et al, 2009).…”

“…Smoking, alcohol, and chewing tobacco and betel quid (synergistic relationship) are the main risk factors for this type of cancer (Lin et al, 2005;Monteiro et al, 2013;Neville and Day, 2002;Warnakulasuriya, 2009). Poor eating habits, sun overexpsoure, viral infections (particularly human papillomavirus (HPV)), poor oral hygiene, and ISSN: 2198-4093 www.bmrat.org socio-economic factors are also important risk factors for lip and oral cavity cancers ( de Camargo Cancela et al, 2010;Farah et al, 2014;Funk et al, 2002;Ribeiro et al, 2015;Warnakulasuriya, 2009). …”