Antibacterial and Microstructure Properties of Titanium Surfaces Modified with Ag-Incorporated Nanotube Arrays

Li, Guangzhong; Zhao, Qing; Yang, Huilin; Cheng, Li

doi:10.1590/1980-5373-mr-2015-0534

Cited by 16 publications

(7 citation statements)

References 24 publications

(23 reference statements)

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“…The oral environment possesses irregular surfaces where more bacteria are retained than in smooth areas, as the bacteria are protected from salivary fluid flow, tongue, and muscle action. Thus, smooth surfaces are less likely to be associated with bacterial adhesion [ 15 , 24 , 25 , 26 ]. Our previous studies showed that QTiN and SiC coatings were more hydrophobic than TiN and uncoated surfaces, presenting lower bacteria adhesion [ 27 , 28 ].…”

Section: Discussionmentioning

confidence: 99%

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Novel Coatings to Minimize Bacterial Adhesion and Promote Osteoblast Activity for Titanium Implants

Camargo

Roy

Carey

et al. 2020

JFB

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Titanium nitride (TiN) and silicon carbide (SiC) adhesion properties to biofilm and the proliferation of human osteoblasts were studied. Quaternized titanium nitride (QTiN) was produced by converting the surface nitrogen on TiN to a positive charge through a quaternization process to further improve the antibacterial efficiency. The SiC required a nitridation within the plasma chamber of the surface layer before quaternization could be carried out to produce quaternized SiC (QSiC). The antimicrobial activity was evaluated on the reference strains of Porphyromonas gingivalis for 4 h by fluorescence microscopy using a live/dead viability kit. All the coatings exhibited a lower biofilm coverage compared to the uncoated samples (Ti—85.2%; TiN—24.22%; QTiN—11.4%; SiC—9.1%; QSiC—9.74%). Scanning Electron Microscope (SEM) images confirmed the reduction in P. gingivalis bacteria on the SiC and TiN-coated groups. After 24 h of osteoblast cultivation on the samples, the cell adhesion was observed on all the coated and uncoated groups. Fluorescence images demonstrated that the osteoblast cells adhered and proliferated on the surfaces. TiN and SiC coatings can inhibit the attachment of Porphyromonas gingivalis and promote osteoblast adhesion on the titanium used for implants. These coatings may possess the ability to prevent the development of peri-implantitis and stimulate osteointegration.

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Section: Discussionmentioning

confidence: 99%

“…In vitro studies have been performed on bacterial adhesion to titanium implants [ 10 , 16 , 24 , 25 , 27 , 29 , 30 , 31 ]. P. gingivalis was chosen for this study because these bacteria are a common human pathogen found in peri-implantitis.…”

Section: Discussionmentioning

confidence: 99%

Novel Coatings to Minimize Bacterial Adhesion and Promote Osteoblast Activity for Titanium Implants

Camargo

Roy

Carey

et al. 2020

JFB

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“…These reactions lead to the destruction of the cell membrane that promotes Ag ions' entry into the cell, reacts with vital enzyme's thiol groups, and by damaging the DNA, it stops bacteria's ability to replicate. Furthermore, silver ions trigger free radicals producing ROS with high toxicity that cause damage to cellular structures (Figure 1) [62,63].…”

Section: The Antibacterial Activity Of Np Ag-deposited Into Ntt Used mentioning

confidence: 99%

“…Li et al, 2016 [62] demonstrated that untreated Ti has no antibacterial activity. Compared to pure Ti, NTT inhibited many bacterial colonies' growth, implying that NTT have valuable antibacterial properties [62]. Many researchers have shown that the Ag/NTT group significantly inhibited several bacterial strains, suggesting that Ag ions released from Ag/NTT exhibit a significant bactericidal effect [75,81,82].…”

Section: The Antibacterial Activity Of Np Ag-deposited Into Ntt Used mentioning

confidence: 99%

Silver-Deposited Nanoparticles on the Titanium Nanotubes Surface as a Promising Antibacterial Material into Implants

Coman

Mare

Tănase

et al. 2021

Metals

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The main disadvantage of the implants is the associated infections. Therefore, in the long term, the possibility of improving the antibacterial capacity of different types of implants (dental, orthopedic) is being researched. The severity of the problem lies in the increasing bacterial resistance and finding appropriate alternative treatments for infectious diseases, which is an important research field nowadays. The purpose of this review is to draw a parallel between different studies analyzing the antibacterial activity and mechanism of silver nanoparticles (NP Ag) deposited on the titanium nanotubes (NTT), as well as the analysis of the NP Ag toxicity. This review also provides an overview of the synthesis and characterization of TiO2-derived nanotubes (NT). Thus, the analysis aims to present the existing knowledge to better understand the NP Ag implants benefits and their antibacterial activity.

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“…Improving the dental restoration’s lifetime through careful selection of materials has been the focus of many previous studies, where traditionally different alloys and metal systems have been evaluated for biocompatibility and antibacterial properties [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ]. Although the majority of these approaches have used methods involving the bulk system, use of thin films can offer an easier avenue to maintaining the integrity of the restoration while grafting unique properties to selective areas where the film is applied.…”

Section: Introductionmentioning

confidence: 99%

Anti-Bacterial Properties and Biocompatibility of Novel SiC Coating for Dental Ceramic

Camargo

Mohiuddeen

Fares

et al. 2020

JFB

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A 200 nm plasma-enhanced chemical vapor-deposited SiC was used as a coating on dental ceramics to improve anti-bacterial properties for the applications of dental prosthesis. A thin SiO2 (20 nm) in the same system was deposited first, prior to SiC deposition, to improve the adhesion between SiC to dental ceramic. Silane and methane were the precursors for SiC deposition, and the SiO2 deposition employed silane and nitrous oxide as the precursors. SiC antimicrobial activity was evaluated on the proliferation of biofilm, Streptococcus sanguinis, and Streptococcus mutans on SiC-coated and uncoated dental ceramics for 24 h. The ceramic coating with SiC exhibited a biofilm coverage of 16.9%, whereas uncoated samples demonstrated a significantly higher biofilm coverage of 91.8%, measured with fluorescence and scanning electron microscopic images. The cytotoxicity of the SiC coating was evaluated using human periodontal ligament fibroblasts (HPdLF) by CellTiter-BlueCell viability assay. After 24 h of HPdLF cultivation, no obvious cytotoxicity was observed on the SiC coating and control group; both sets of samples exhibited similar cell adhesion and proliferation. SiC coating on a ceramic demonstrated antimicrobial activity without inducing cytotoxic effects.

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Antibacterial and Microstructure Properties of Titanium Surfaces Modified with Ag-Incorporated Nanotube Arrays

Cited by 16 publications

References 24 publications

Novel Coatings to Minimize Bacterial Adhesion and Promote Osteoblast Activity for Titanium Implants

Novel Coatings to Minimize Bacterial Adhesion and Promote Osteoblast Activity for Titanium Implants

Silver-Deposited Nanoparticles on the Titanium Nanotubes Surface as a Promising Antibacterial Material into Implants

Anti-Bacterial Properties and Biocompatibility of Novel SiC Coating for Dental Ceramic

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