Average direct costs of outpatient, hospital, and home care provided to patients with chronic wounds

Ruiz, Paula Buck de Oliveira; Lima, Antônio Fernandes Costa

doi:10.1590/1980-220x-reeusp-2022-0295en

Cited by 3 publications

(1 citation statement)

References 20 publications

(25 reference statements)

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“…Brazil is a quickly developing nation, with its healthcare systems becoming more and more sophisticated. With a large population its national healthcare spend is significant, 21 and this includes wounds (Table 1). A literature search shows several studies have been carried out to highlight the cost of wounds within Brazil 22,23 .…”

Section: Regional Analysismentioning

confidence: 99%

Estimating the cost of wounds both nationally and regionally within the top 10 highest spenders

Queen,

Harding

2024

International Wound Journal

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Section: Regional Analysismentioning

confidence: 99%

Estimating the cost of wounds both nationally and regionally within the top 10 highest spenders

Queen,

Harding

2024

International Wound Journal

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Pyolytics as a product of the physical–chemical repurposing of antiseptics and an alternative to larval therapy for chronic wounds

Urakov,

Urakova,

Reshetnikov

et al. 2024

Rev Clin Pharm Drug Ther

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It is shown that traditional treatment of chronic wounds is a course of daily single procedures of cleansing the wound surface from purulent-necrotic masses by mechanical and medicinal methods, accompanied by regular renewal of wound dressings. In this case, the procedures of medicinal wound cleansing last 10 - 15 minutes between the replacement of "old" wound dressings with "new" wound dressings. According to the established practice, medicinal sanitation of infected and purulent wounds during dressings consists in irrigation of the wound surface with cleansing solutions, solutions of antiseptics and/or antibiotics. In severe cases, the above therapy is supplemented with live larvae of the necrophage fly, which are injected into purulent-necrotic masses and left in them under wound dressings until complete cleansing of wounds from pus. Nevertheless, the effectiveness of the generally accepted course treatment of chronic wounds remains insufficiently high. It is reported that the use of pyolytics and their supplementation with wound dressings made in the form of warm wet compresses, which create a local greenhouse effect in wounds, can accelerate the healing of chronic wounds. It is shown that pyolytics is a group of antiseptics developed in Russia, which are warm alkaline solutions of hydrogen peroxide, which in interaction with purulent-necrotic masses very quickly dissolve and foam them. As a result of interaction with pyolytics, thick purulent immediately turns into fluffy oxygenated foam. It is shown that pyolytics have been developed due to physicochemical repurposing of aqueous solutions of sodium hydrogen carbonate and hydrogen peroxide. To accelerate the healing of chronic wounds it was proposed to irrigate the surface of chronic wounds with a solution of 3% hydrogen peroxide and 2-10% sodium bicarbonate, heated to a temperature of +37 - +45C, having alkaline activity at pH 8.4 - 8.5 and enriched with dissolved carbon dioxide or oxygen (due to excess pressure of 0.2 ATM). The essence of the invented technology of treatment of chronic wounds with the use of pyolytics is indicated and the results of treatment of chronic wounds with pyolytics in combination with warm moist dressings-compresses are given, which confirm the presence of wound-healing effect. Consequently, physical and chemical re-profiling of antiseptics allows turning them into effective pyolytics, and the combination of pyolytics with warm wound dressings made in the form of warm moist compresses, which create a local greenhouse effect in wounds, allows accelerating the healing of chronic wounds.

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Modern Approaches in Wounds Management

Tatarusanu,

Lupascu,

Profire

et al. 2023

Polymers

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Wound management represents a well-known continuous challenge and concern of the global healthcare systems worldwide. The challenge is on the one hand related to the accurate diagnosis, and on the other hand to establishing an effective treatment plan and choosing appropriate wound care products in order to maximize the healing outcome and minimize the financial cost. The market of wound dressings is a dynamic field which grows and evolves continuously as a result of extensive research on developing versatile formulations with innovative properties. Hydrogels are one of the most attractive wound care products which, in many aspects, are considered ideal for wound treatment and are widely exploited for extension of their advantages in healing process. Smart hydrogels (SHs) offer the opportunities of the modulation physico-chemical properties of hydrogels in response to external stimuli (light, pressure, pH variations, magnetic/electric field, etc.) in order to achieve innovative behavior of their three-dimensional matrix (gel–sol transitions, self-healing and self-adapting abilities, controlled release of drugs). The SHs response to different triggers depends on their composition, cross-linking method, and manufacturing process approach. Both native or functionalized natural and synthetic polymers may be used to develop stimuli-responsive matrices, while the mandatory characteristics of hydrogels (biocompatibility, water permeability, bioadhesion) are preserved. In this review, we briefly present the physiopathology and healing mechanisms of chronic wounds, as well as current therapeutic approaches. The rational of using traditional hydrogels and SHs in wound healing, as well as the current research directions for developing SHs with innovative features, are addressed and discussed along with their limitations and perspectives in industrial-scale manufacturing.

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Average direct costs of outpatient, hospital, and home care provided to patients with chronic wounds

Cited by 3 publications

References 20 publications

Estimating the cost of wounds both nationally and regionally within the top 10 highest spenders

Estimating the cost of wounds both nationally and regionally within the top 10 highest spenders

Pyolytics as a product of the physical–chemical repurposing of antiseptics and an alternative to larval therapy for chronic wounds

Modern Approaches in Wounds Management

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