Transformações químicas de lignanas isoladas de Virola sebifera em análogos de podofilotoxina

Fernandes, João B.; Vieira, Paulo C.; Fraga, Regina Lúcia

doi:10.1590/1809-43921988185442

Cited by 2 publications

(1 citation statement)

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“…Bueno et al ,16 studying the consumption of the leaves of Ligustrum lucidum Ait (Oleaceae), Sesamum indicum L (Pedaliacaeae) and V sebifera (Myristicaceae) by colonies of the leaf‐cutting ant Atta sexdens L, observed that the ants were selective, and V sebifera was the last one to be picked up. Fernandes et al 17 found that the leaves of V sebifera contain lignans, some of them of seasonal occurrence, including sesamin. Sesame oil18 is used as a synergist of some insecticides due to the presence of sesamin which also displays antifungal19 and antibacterial activity 20.…”

Section: Introductionmentioning

confidence: 99%

Toxicity of synthetic piperonyl compounds to leaf‐cutting ants and their symbiotic fungus

Victor

Crisóstomo

Bueno

et al. 2001

Pest Management Science

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The development of Leucoagaricus gongylophorus, the fungus cultured by the leaf-cutting ant Atta sexdens was inhibited in vitro by synthetic compounds containing the piperonyl group. In addition, worker ants that were fed daily on an artificial diet to which these compounds were added had a higher mortality rate than the controls. The inhibition of the fungal growth increased with the size of the carbon side chain ranging from C1 through C8 and decreasing thereafter. 1-(3,4-Methylenedioxybenzyloxy)octane (compound 5) was the most active compound and inhibited the fungal development by 80% at a concentration of 15 micrograms ml-1. With worker ants the toxic effects started with compound 5 and increased with the number of carbons in the side chain. Thus, for the same concentration (100 micrograms ml-1) the mortality rates observed after 8 days of diet ingestion were 82%, 66% and 42%, for 1-(3,4-methylenedioxybenzyloxy)decane, 1-(3,4-methylenedioxybenzyloxy)dodecane and compound 5, respectively, whereas with commercial piperonyl butoxide the mortality was 68%. The latter compound, which is known as a synergist insecticide, was as inhibitory to the symbiotic fungus as the synthetic compound 5. The possibility of controlling these insects in the future using compounds that can target simultaneously both organisms is discussed.

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Section: Introductionmentioning

confidence: 99%